Zobrazeno 1 - 10
of 8 171
pro vyhledávání: ''
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
The ingestion of excess lipids often produces the accumulation of liver fat. The modulation of diet energy partition affects this process and other metabolic responses, and oestrogens and androgens are implied in this process. Ten-week-old male and f
Autor:
Min Liu, Ling Shen, Andromeda M. Nauli, Madison Bingamon, Qing Yang, Patrick Tso, Yvonne M. Ulrich-Lai, David Q.-H. Wang
Publikováno v:
J Physiol
Key points Significant differences in intestinal lipid absorption and lymphatic transport were found between female and male animals. Estrogen treatment significantly reduced [3 H]-triacylglycerol (TAG) lymphatic output through suppressing TAG transp
Autor:
Vinayak Gupta, Poovitha Sundar, Nitish R. Mahapatra, Bhargavi Natarajan, S Santosh Reddy, Vikas Arige, Abrar A. Khan, Manoj Kumar Barthwal
Publikováno v:
Journal of Molecular and Cellular Cardiology. 158:140-152
3-Hydroxy-3-methyl glutaryl-coenzyme A reductase (Hmgcr) encodes the rate-limiting enzyme in the cholesterol biosynthesis pathway. The regulation of Hmgcr in rat models of genetic hypertension (viz. Spontaneously Hypertensive Rat [SHR] and its normot
Autor:
Gehan B A Youssef, Ehab Yahya Abdelhiee, Ashraf Elkomy, Sabreen E. Fadl, Mohamed Aboubakr, Walied Abdo, Ahmed M. Soliman, Asmaa Elsayed, Reda Elkammar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Cisplatin (CP) is one of the most frequently used chemotherapy agents. The objective of this design was to determine the ameliorative effect of lycopene (LP) and/or N-acetylcysteine (NAC) in rats with hepatic and renal toxicity induced by CP. Rats we
Publikováno v:
Turkish Journal of Medical Sciences
Background/aim The aim of this study is to determine the effects of different concentrations of albendazole and lansoprazole, which were benzimidazole derivatives, on endocrinologic and biochemical parameters in experimental type 2 diabetic (T2D) rat
Autor:
Masao Sato, Xingyu Yuan, Bungo Shirouchi, Li Tao Tong, Taiki Akasaka, Takuya Mizokami, Yasutake Tanaka, Yumiko Furukawa, Wei Ting Tsai, Toshihiro Kumamaru, Yoshiko Toyosawa, Yutaro Minobe, Zhe Jiang, Motonori Miyago, Yumi Fukuda
Publikováno v:
Journal of the Science of Food and Agriculture. 101:6417-6423
BACKGROUND Rice α-globulin has been reported to have serum cholesterol-lowering activity in rats. However, it is still unclear whether α-globulin exerts this effect when taken as one of the dietary components. In the present study, we investigated
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Zinc oxide nanoparticles (ZnO NPs) demonstrate potential positive effects on reproduction. However, their protective role against the reproductive toxicity pollutants has not yet been adequately studied at the molecular level. This study was designed
Publikováno v:
Biotechnology and Applied Biochemistry. 69:668-675
Hyperlipidemia is a common metabolic disorder in the general population, which may arise in hypothyroidism. Apelin is an endogenous ligand that acts as an adiponectin, and is involved in energy storage and metabolism. This study evaluated the effects
Autor:
Fan Xiaohang, Qiang Hao, Qinghua Hu, Shengquan Luo, Rui Xiao, Ting Zhang, Matthieu Ruiz, Xianqin Zeng, Ping Yuan, Tian Feng, Jin-Ming Liu, Jian-Guo He, Liping Zhu, Fangbo Liu, Zeshuai Chen, Jocelyn Dupuis, Mengxiang Sun
Publikováno v:
Circulation. 143:1775-1792
Background: The mevalonate pathway generates endogenous cholesterol and intermediates including geranylgeranyl pyrophosphate (GGPP). By reducing GGPP production, statins exert pleiotropic or cholesterol-independent effects. The potential regulation o
Autor:
Ahmed T Al Meanazel, Osaid T. Al Meanazel, Ehab M. Elzayat, Mohamed M. Badran, Saleh A Alanazi, Abdullah H. Alomrani, Fars K. Alanazi, Gamaleldin I. Harisa
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 914-926 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 914-926 (2021)
This study aimed to utilize cholesterol conjugation of 5-fluorouracil (5-FUC) and liposomal formulas to enhance the partitioning of 5-FU into low density lipoprotein (LDL) to target hepatocellular carcinoma (HCC). Thus, 5-FU and 5-FUCwere loaded into