Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yutaka Yoshikawa"'
Autor:
Kengo Sasaki, Naoko Ikuta, Yutaka Yoshikawa, Gerald Rimbach, Takahiro Furune, Hinako Okamoto, Keiji Terao, Nanako Nihei
Publikováno v:
BioFactors. 44:336-347
We investigated the effect of α-cyclodextrin (α-CD) on the bacterial populations of gut microbiota, production of organic acids, and short-chain fatty acids (SCFAs), and lipid metabolism in obese mice induced by feeding a high-fat diet (HFD). Male
Autor:
Franc Perdih, Yutaka Yoshikawa, Anton Meden, Keiichi Maejima, Hiroyuki Yasui, Tanja Koleša-Dobravc
Publikováno v:
New Journal of Chemistry. 42:3619-3632
Vanadium(V) compounds with 3,5-difluoropicolinic acid (HpicFF) and 3-hydroxypicolinic acid (H2hypic) and zinc(II) compounds with HpicFF, H2hypic and 4-methylhydroxypicolinic acid (HpicCH2OH) in the presence or absence of pyridine (py), 4-(dimethylami
Autor:
Moe Tamura, Hiroyuki Yasui, Yutaka Yoshikawa, Kaname Sasaki, Ryota Saito, Saya Kawano, Akihiro Kato
Publikováno v:
New Journal of Chemistry. 41:5572-5581
The newly designed 1-(arylmethyl)-2,5-dihydro-4-hydroxy-5-oxo-1H-pyrrole-3-carboxamides (1a–e) were synthesized by using N-tritylated acrylamide as a starting material, and their zinc(II) complexes (10a–e) were readily prepared by simply mixing 1
Autor:
Anton Meden, Keiichi Maejima, Tanja Koleša-Dobravc, Hiroyuki Yasui, Yutaka Yoshikawa, Franc Perdih
Publikováno v:
New Journal of Chemistry. 41:735-746
Vanadium(V) compounds with 5-cyanopicolinato acid (HpicCN), pyrazine-2-carboxylic acid (Hprz) and 3-aminopyrazine-2-carboxylic acid (HprzNH2) and zinc compounds with HpicCN in the presence of 4-aminopyridine (4apy), pyridine (py) and 1,10-phenanthrol
Autor:
Shiliang Li, Matthias Karck, Gábor Szabó, Ayhan Atmanli, E Barnucz, Yutaka Yoshikawa, Kristóf Hirschberg, Sivakkanan Loganathan, Sevil Korkmaz, Tamás Radovits, Hiroyuki Yasui, Péter Hegedűs
Publikováno v:
Experimental Biology and Medicine. 240:1247-1255
The pathophysiology of ischemic myocardial injury involves cellular events, reactive oxygen species, and an inflammatory reaction cascade. The zinc complex of acetylsalicylic acid (Zn(ASA)2) has been found to possess higher anti-inflammatory and lowe
Autor:
Yutaka Yoshikawa, Akihiro Tai, Hiroki Kakuta, Fuminori Ohsawa, Makoto Makishima, Hiroyuki Yasui, Shoya Yamada
Publikováno v:
Biological and Pharmaceutical Bulletin. 35:629-633
Retinoid X receptor (RXR) agonists are reported to exhibit blood glucose-lowering action owing to peroxisome proliferator-activated receptor (PPAR)/RXR or liver X receptor (LXR)/RXR activation, but may also cause adverse effects such as blood triglyc
Publikováno v:
Chemical and Pharmaceutical Bulletin. 60:1096-1104
Zn(II) complexes are expected to be useful in the treatment of diabetes mellitus because of the hypoglycemic effect produced by its insulin-mimetic activity. Previous reports indicated that Zn(II) complexes with coordinating sulfur exhibit higher ins
Publikováno v:
Metallomics. 2:67-73
We investigated the effects of divalent alkaline earth and first-row transition metal and zinc ions on α-glucosidase activityin vitro and in vivo. CuSO4 and ZnSO4 exhibited a high α-glucosidase inhibitory effect in vitro. The IC50 values of CuSO4 w
Publikováno v:
Journal of Inorganic Biochemistry. 103:567-574
Vanadyl sulfate (VOSO(4)) has been clinically tested in diabetic patients since 1995. Oral administrations of VOSO(4) improved the type 2 diabetic state with respect to plasma glucose, HbA(1c), and fructosamine levels. The development of toxicity by
Autor:
Hiroyuki Yasui, Ayhan Atmanli, Shiliang Li, Sevil Korkmaz-Icöz, Yutaka Yoshikawa, Matthias Karck, Paige Brlecic, Mihály Ruppert, Peter Hegedüs, Gábor Szabó, Tamás Radovits
Publikováno v:
The journal of physiological sciences : JPS. 66(2)
We recently demonstrated that the pre-treatment of rats with zinc and acetylsalicylic acid complex in the form of bis(aspirinato)zinc(II) [Zn(ASA)2] is superior to acetylsalicylic acid in protecting the heart from acute myocardial ischemia. Herein, w