Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Xiaofeng Tian"'
Autor:
Weili Wang, Chunrong Ren, Laixue Pang, Kangning Sun, Mingchen Zhang, Xiaofeng Tian, Yongling Ding, Jinglou Zhang, Huadong Sun
Publikováno v:
Journal of Materials Research and Technology, Vol 13, Iss, Pp 1350-1362 (2021)
In order to achieve specific enrichment of target glycoproteins, double molecular recognition ligands functionalized surface solid-phase adsorption materials that can play a role under physiological pH conditions, have obvious advantages. In this wor
Autor:
Zhao Chen, Xiaodong Ma, Li Lv, Xiaofeng Tian, Fan Tang, Huanyu Zhao, Yang Li, Jihong Yao, Zhecheng Wang, Junjun Zhou, Dongcheng Feng, Yan Zhao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss, Pp 751-763 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
We previously found that inhibition of p66Shc confers protection against hepatic stellate cell (HSC) activation during liver fibrosis. However, the effect of p66Shc on HSC proliferation, as well as the mechanism by which p66Shc is modulated, remains
Autor:
Xiaofeng Tian, Dongyan Gao, Ruimin Sun, Jihong Yao, Yu Sun, Yan Zhao, Ruiwen Wang, Rong Fu, Yunfei Geng, Zhecheng Wang, Meiyang Zhu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Fatty acid β-oxidation is an essential pathogenic mechanism in nonalcoholic fatty liver disease (NAFLD), and TATA-box binding protein associated factor 9 (TAF9) has been reported to be involved in the regulation of fatty acid β-oxidation. However,
Autor:
Yue Wang, Yan Zhao, Zhecheng Wang, Ruimin Sun, Boyang Zou, Ruixi Li, Deshun Liu, Musen Lin, Junjun Zhou, Shili Ning, Xiaofeng Tian, Jihong Yao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Pyroptosis is a newly discovered form of cell death. Peroxiredoxin 3 (PRX3) plays a crucial role in scavenging reactive oxygen species (ROS), but its hepatoprotective capacity in acetaminophen (APAP)-induced liver disease remains unclear. The aim of
Autor:
Junjun Zhou, Yan Zhao, Ruimin Sun, Jihong Yao, Dongcheng Feng, Rong Fu, Xiaofeng Tian, Zhecheng Wang, Ruiwen Wang, Li Lv
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2019 (2019)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Alcohol abuse has become common worldwide and has been recognized as a major cause of chronic alcoholic liver disease (ALD). ALD encompasses a complex process that includes a broad scope of hepatic lesions, ranging from steatosis to cirrhosis. In par
Autor:
Yan Zhao, Deshun Liu, Yang Li, Zhanyu Wang, Donghai Tian, Xiaofeng Tian, Feng Zhang, Shili Ning, Dongcheng Feng, Ruimin Sun, Jihong Yao
Publikováno v:
Cell Death and Differentiation
Ferroptosis is a recently identified form of regulated cell death defined by the iron-dependent accumulation of lipid reactive oxygen species. Ferroptosis has been studied in various diseases such as cancer, Parkinson’s disease, and stroke. However
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species
Autor:
Zhenming Gao, Xiaofeng Tian, Zhecheng Wang, Li Lv, Dongcheng Feng, Huanyu Zhao, Ning Zhang, Yan Hu, Xiaohan Zhai, Jihong Yao, Yan Zhao, Musen Lin
Publikováno v:
Theranostics
Background: p66Shc is a redox enzyme that mediates mitochondrial reactive oxygen species (ROS) generation. p66Shc inhibition confers protection against liver injury, however, its functional contribution to liver fibrosis remains unclear. The aim of t
Autor:
Yan Zhao, Yan Hu, Zhao Chen, Yang Li, Shili Ning, Jihong Yao, Zhecheng Wang, Deshun Liu, Xiaofeng Tian, Dongcheng Feng
Publikováno v:
Theranostics
Background: Oxidative stress has emerged as an essential factor in the pathogenesis of intestinal ischemia/reperfusion (I/R) injury. The adaptor protein p66Shc is a key regulator of reactive oxygen species (ROS) generation and a mediator of I/R damag
Publikováno v:
World Journal of Gastroenterology. 24:833-843
Fish oil alleviates liver injury induced by intestinal ischemia/reperfusion via AMPK/SIRT-1/autophagy pathway
Autor:
Wasim Qasim, Xiaofeng Tian, Guangzhi Wang, Yang Li, Jihong Yao, Zhenlu Li, Fuwen Luo, Zhao Chen, Dongcheng Feng, Shili Ning, Guo Zu
Publikováno v:
Clinical Science. 131:759-773
Intestinal epithelial oxidative stress and apoptosis constitute key pathogenic mechanisms underlying intestinal ischemia/reperfusion (I/R) injury. We previously reported that the adaptor 66 kDa isoform of the adaptor molecule ShcA (p66Shc)-mediated p