Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Hong-Yuan Chen"'
Publikováno v:
CCS Chemistry. 4:2221-2227
Electrochemical microscopy has been developed in the past decades for imaging biomolecules in single cells; however, electrochemical visualization of an intracellular protein in one cell is difficu...
Publikováno v:
Analytical Chemistry. 93:14892-14899
Lysosomal acidification is essential for its degradative function, and the flux of H+ correlated with that of K+ in lysosomes. However, there is little research on their correlation due to the lack of probes that can simultaneously image these two io
Autor:
Yuqin Wang, Hong-Yuan Chen, Shuanghong Yan, Shuo Huang, Pingping Fan, Panke Zhang, Shanyu Zhang, Xiaoyu Du
Publikováno v:
Analytical Chemistry. 93:14161-14168
Blockers of pore-forming toxins (PFTs) limit bacterial virulence by blocking relevant channel proteins. However, screening of desired blockers from a large pool of candidate molecules is not a trivial task. Acknowledging its advantages of low cost, h
Autor:
Weiming Guo, Yuqin Wang, Liying Wang, Shuanghong Yan, Yao Liu, Panke Zhang, Shuo Huang, Jinyue Zhang, Fubo Ma, Yu Wang, Shanyu Zhang, Jiao Cao, Hong-Yuan Chen
Publikováno v:
Nano Letters. 21:6703-6710
Diverse functions of proteins, including synthesis, catalysis, and signaling, result from their highly variable amino acid sequences. The technology allowing for direct analysis of protein sequences, however, is still unsatisfactory. Recent developme
Publikováno v:
ACS Applied Nano Materials. 4:7244-7252
Aggregation-induced emission (AIE) has attracted considerable attention in designing high-performance emitters for both photoluminescence (PL) and electrochemiluminescence (ECL). In this study, to prepare AIE-active polymer dots (Pdots) with efficien
Publikováno v:
The Analyst. 146:1548-1551
Drop-on-demand microkits with a diameter of ∼20 μm are used to measure the activity of acetylcholinesterase (AChE) in a brain slice with single-cell resolution. The relative standard deviation from 25 cellular regions reached 73.3% exhibiting the
Autor:
Shuanghong Yan, Jiao Cao, Shuo Huang, Shanyu Zhang, Panke Zhang, Jinyue Zhang, Sha Wang, Wendong Jia, Yuqin Wang, Hong-Yuan Chen
Publikováno v:
Analytical Chemistry. 93:1529-1536
Gold(I) compounds are known to bind sulfur-containing proteins, forming the basis in the design of gold(I)-based drugs. However, the intrinsic molecular mechanism of the chemical reaction is easily hidden when monitored in ensemble. We have previousl
Autor:
Yang Li, Yixiang Cheng, Wei Zhao, Yiwu Quan, Jing-Juan Xu, Hang Gao, Nan Zhang, Hong-Yuan Chen
Publikováno v:
Science China Chemistry. 63:715-721
Trace Ir(III) complex enhanced aggregation-induced electrochemiluminescence (AIECL) of poly-tetraphenylethene (pTPE) in aqueous media was investigated for the first time. The poly-TPE end-capped by Ir(III) complex (Ir@pTPE) and its corresponding mode
Publikováno v:
Analytical Chemistry. 91:12553-12559
This paper develops an efficient electrochemiluminescence (ECL) enhancement strategy on closed bipolar electrode for the detection of prostate specific antigen (PSA). We first synthesized a cyclometalated iridium(III) complex (pq)2Irbza with high ECL
Publikováno v:
Analytical chemistry. 93(36)
Single-molecule localization allows determining the underlying biological and biochemical processes and promotes the development of super-resolution imaging techniques. Here, we present an optical technique of tracking the motion of a single nanopart