Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Toshiaki Makino"'
Publikováno v:
Journal of Natural Medicines
Paclitaxel, a standard chemotherapeutic agent for several types of cancer, including ovarian, breast, and non-small-cell lung cancer, causes peripheral neuropathy as an adverse effect in 60–70% of the patients. The utility of combination therapy wi
Autor:
Seçil Sarıkaya Aydın, Vahap Kutluay, Toshiaki Makino, Makoto Inoue, Ümmühan Harput, İclal Saraçoğlu
Publikováno v:
İstanbul Journal of Pharmacy. 51:98-104
Background and Aims: Hypericum microcalycinum Boiss. & Heldr. is used for inflammatory diseases in Anatolia. The involve ment of liver X receptors (LXRs) and free radicals in inflammatory diseases, activation of LXRs, and high radical contents in can
Autor:
Toshiaki Makino
Publikováno v:
Journal of Natural Medicines
I investigated the causative agents of licorice-induced pseudoaldosteronism, which is a frequent side effect of Japanese traditional Kampo medicines. Glycyrrhizin (GL), the main ingredient of licorice, is absorbed after being metabolized to glycyrrhe
Publikováno v:
Plant Biotechnology. 37:293-299
Anthraquinones are widely distributed in various organisms and known as bioactive ingredients. Some of the anthraquinones accumulate as glycosides in higher plants. Plant secondary product glycosyltransferases (PSPGs) are the well-characterized enzym
Autor:
Kan'ichiro Ishiuchi, Koshi Asai, Yoshiaki Tabuchi, Kewen Ding, Xin Xu, Daiki Kato, Toshiaki Makino, Misato Ota
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
We have previously discovered that heated honey but not unheated honey could induce the secretion of granulocyte-colony stimulating factor (G-CSF) in the MCE301 intestinal epithelial cells. The objective of this study was to identify compounds in hon
Autor:
Takao Namiki, Koichiro Tanaka, Kunihiko Obara, Tsukasa Fueki, Toshiaki Makino, Ryudo Kawahara
Publikováno v:
Journal of Natural Medicines
Graphic abstract Unprocessed dried tuberous root of Pinellia ternata (Pinellia Tuber) has been used as a component of traditional Japanese Kampo medicine, while this crude drug is usually used after processing with Ginger in traditional Chinese medic
Autor:
Kan'ichiro Ishiuchi, Yasuhito Maki, Takao Namiki, Tetsuhiro Yoshino, Masaru Mimura, Kenji Watanabe, Toshiaki Makino, Keiko Ogawa-Ochiai, Kanon Takahashi, Tomonori Nakamura, Kiyoshi Minamizawa
Publikováno v:
Archives of Toxicology. 93:3111-3119
Liquorice [main ingredient, glycyrrhizin (GL)] is widely used as a food sweetener and herbal medicine. Occasionally, liquorice consumption causes pseudoaldosteronism as a side effect which causes oedema, hypokalaemia, and hypertension due to hyperact
Autor:
Tetsuhiro Yoshino, Saori Shimada, Masato Homma, Toshiaki Makino, Masaru Mimura, Kenji Watanabe
Publikováno v:
Frontiers in Nutrition
Frontiers in Nutrition, Vol 8 (2021)
Frontiers in Nutrition, Vol 8 (2021)
Licorice, the dried root or stolon of Glycyrrhiza glabra or G. ularensis, is commonly used worldwide as a food sweetener or crude drug. Its major ingredient is glycyrrhizin. Hypokalemia or pseudoaldosteronism (PsA) is one of the most frequent side ef
Autor:
Chiharu Miyajima, Daisuke Morishita, Yasumichi Inoue, Masaki Ri, Hajime Mizukami, Kan'ichiro Ishiuchi, Shinsuke Iida, Muneshige Tokugawa, Nobumichi Ohoka, Michiyo Matsuno, Hidetoshi Hayashi, Yuka Itoh, Toshiaki Makino, Chisane Kujirai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
The unfolded protein response (UPR) controls protein homeostasis through transcriptional and translational regulation. However, dysregulated UPR signaling has been associated with the pathogenesis of many human diseases. Therefore, the compounds modu
Publikováno v:
Journal of natural medicines. 76(1)
Shin'iseihaito (Xinyiqingfeitang) is a formula of traditional Japanese Kampo medicine and traditional Chinese medicine (TCM) and for chronic sinusitis. However, the precise action mechanism has been unknown. We examined the effect of shin'iseihaito e