Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Steve Turner"'
Autor:
Louisa Owens, Peter N. Le Souëf, Ingrid A. Laing, Steve Turner, Jasminka Murdzoska, Guicheng Zhang
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 200:462-470
Rationale: In utero tobacco exposure is associated with reduced lung function from infancy. Antioxidant enzymes from the glutathione S-transferase (GST) family may protect against these lung functi...
Autor:
Steve Turner, Husam Ahmed
Publikováno v:
Pediatric Pulmonology. 54:778-787
Severe asthma is a relatively uncommon condition in children but one which causes morbidity, occasionally mortality, and is a challenging condition to manage. There are several definitions of severe asthma, which have a common theme of poor control d
The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013
Autor:
Gareth Owen, Mark Williams, Paula de Matos, Janna Hastings, Steve Turner, Christoph Steinbeck, Venkatesh Muthukrishnan, Bhavana Harsha, Adriano Dekker, Namrata Kale, Marcus Ennis
Publikováno v:
Nucleic Acids Research
ChEBI (http://www.ebi.ac.uk/chebi) is a database and ontology of chemical entities of biological interest. Over the past few years, ChEBI has continued to grow steadily in content, and has added several new features. In addition to incorporating all
Autor:
Garry Michael Walsh, Steve Turner, Daniella S. Cornish, Helen Richardson, David Miller, Emily J. Pringle, Graham Devereux
Publikováno v:
Pediatric Pulmonology. 47:1215-1225
Objective The present study was designed to test the hypothesis that airway epithelial cell (AEC) mediator release is similar in upper and lower airway AEC in children. Methods Nasal and bronchial AEC were collected by brushings from children schedul
Autor:
Thomas Engelhardt, Daniella Spiteri, Neil McInnes, David Miller, Graham Devereux, Garry Michael Walsh, Matthew Davidson, Steve Turner, Sean Semple, Alison Scaife
Publikováno v:
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health; Volume 13; Issue 4; Pages: 359
International Journal of Environmental Research and Public Health, Vol 13, Iss 4, p 359 (2016)
International Journal of Environmental Research and Public Health; Volume 13; Issue 4; Pages: 359
International Journal of Environmental Research and Public Health, Vol 13, Iss 4, p 359 (2016)
The bronchial airway epithelial cell (BAEC) is the site for initial encounters between inhaled environmental factors and the lower respiratory system. Our hypothesis was that release of pro inflammatory interleukins (IL)-6 and IL-8 from primary BAEC
Publikováno v:
Pituitary. 3:61-65
The use of somatostatin analogues for the treatment of acromegaly is now well established. Recently long-acting preparations of octreotide and lanreotide have been introduced. In this study we have assessed the efficacy and tolerability of the long a
Autor:
Olgica Bakajin, Edward C. Cox, Shirley S. Chan, Thomas Duke, Robert H. Austin, Judith Castelino, N. Darnton, Chia-Fu Chou, Harold G. Craighead, Jongyoon Han, Jonas O. Tegenfeldt, Steve Turner
Publikováno v:
ELECTROPHORESIS. 21:81-90
Micro- and nanofabrication techniques have provided an unprecedented opportunity to create a designed world in which separation and fractionation technologies which normally occur on the macroscopic scale can be optimized by designing structures whic
Autor:
Lester A. Dolak, Johnson Paul D, Chong Kt, Harvey Irving Skulnick, Paul K. Tomich, Michael John Bohanon, Strohbach Joseph Walter, Suvit Thaisrivongs, Steve Turner, K. D. Watenpaugh, M.‐M. Horng, M.N. Janakiraman, R. R. Hinshaw, Paul A. Aristoff, J. C. Lynn, Eric P. Seest, Tommasi Ruben A
Publikováno v:
Journal of Medicinal Chemistry. 41:3467-3476
A broad screening program previously identified phenprocoumon (1) as a small molecule template for inhibition of HIV protease. Subsequent modification of this lead through iterative cycles of structure-based design led to the activity enhancements of
Autor:
Venkatesh Muthukrishnan, Kenneth Haug, Kalai Vanii Jayaseelan, Steve Turner, Gareth Owen, Janna Hastings, Marcus Ennis, Tejasvi Mahendraker, Pablo Conesa, Adriano Dekker, Namrata Kale, Pablo Moreno, Reza M. Salek, Christoph Steinbeck
Publikováno v:
Journal of Cheminformatics
Natural products are of substantial interest in drug discovery and metabolism research, since they represent molecules that have been shaped by natural selection to be bioactive in ways that are useful for a range of applications including as therape
Publikováno v:
ChemInform. 22