Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Stephen I, Wasserman"'
Autor:
Emiko, Ono, Stefanie, Dutile, Shamsah, Kazani, Michael E, Wechsler, Jun, Yang, Bruce D, Hammock, David Nobuhiro, Douda, Yacine, Tabet, Rayan, Khaddaj-Mallat, Marco, Sirois, Chantal, Sirois, Edmond, Rizcallah, Eric, Rousseau, Richard, Martin, E Rand, Sutherland, Mario, Castro, Nizar N, Jarjour, Elliot, Israel, Bruce D, Levy, Stephen I, Wasserman
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 190:886-897
Rationale: Severe asthma is characterized by airway inflammatory responses associated with aberrant metabolism of arachidonic acid. Lipoxins (LX) are arachidonate-derived pro-resolving mediators that are decreased in severe asthma, yet mechanisms for
Autor:
Michael E. Woodman, Frances Tung, Danalyn Manglicmot, Stephen I. Wasserman, Joey P. Ting, Stephen Antonysamy, Jeffrey Alan Dodge, Marijane Russell, Aiping Zhang, Michael J. Chalmers, Spencer B. Jones, Feiyu F. Zhang, Sepideh Afshar, Howard B. Broughton, Jordi Benach, Holly A. Bina, Christopher Groshong, Alfonso Espada
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190850 (2018)
PLoS ONE
PLoS ONE
To date, IL-17A antibodies remain the only therapeutic approach to correct the abnormal activation of the IL-17A/IL-17R signaling complex. Why is it that despite the remarkable success of IL-17 antibodies, there is no small molecule antagonist of IL-
Autor:
Allen F. Ryan, Kwang Pak, David H. Broide, Jörg Ebmeyer, Stephen I. Wasserman, Holger Sudhoff, Umay Ebmeyer
Publikováno v:
Otology & Neurotology. 31:42-47
Hypothesis—Intravenous injection of cultured mast cells can reconstitute the mast cell population in mast cell deficient mice. We hypothesize that injected culture-derived mast cells do not repopulate all tissues equally. Background—Mast cells ar
Publikováno v:
Journal of Allergy and Clinical Immunology. 118:972-976
Autor:
Stephen I. Wasserman
Publikováno v:
Journal of Allergy and Clinical Immunology. 118:976-978
Autor:
Stephen I. Wasserman
Publikováno v:
Journal of Allergy and Clinical Immunology. 118:978-980
Autor:
David A. Coburn, Edward C. Federman, Stephen I. Wasserman, David H. Broide, Anthony J. Cuomo, Lawrence B. Schwarte, Gerald J. Gleich
Publikováno v:
Journal of Allergy and Clinical Immunology. 88:637-648
To assess whether mast cell and eosinophil (EOS) degranulation occurs in the airway of subjects with moderately symptomatic asthma, we have measured levels of preformed mast cell-derived mediators (histamine and tryptase) and EOS-derived mediators (m
Publikováno v:
British Journal of Dermatology. 122:501-512
SUMMARY We report that protoporphyrin (PP) and ultraviolet light (UVA) induces histamine release from rat peritoneal mast cells, mouse bone marrow mast cells and human cutaneous mast cells in a dose- and temperature-dependent manner. The mast-cell ac
Autor:
Stephen I. Wasserman
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 150:S39-S41
A number of new observations have added to our understanding of mast cell biology and the relevance of this cell to the genesis of asthma. The purpose of this review has been to highlight this new information and to refer the reader to extensive revi
Autor:
Stephen I. Wasserman
Publikováno v:
Allergy proceedings : the official journal of regional and state allergy societies. 16(2)
Nedocromil sodium, a pyranoquinolone, was specifically designed as an agent to suppress allergic inflammation. Nedocromil sodium significantly affects not only the early-phase of allergen-induced responses, but also expression of late-phase inflammat