Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Robert Stevens"'
Autor:
Matthew D. Hirschey, Thompson Jw, Scott B. Crown, Paul A. Grimsrud, Robert Stevens, Gregory R. Wagner, Trub A, Donald S. Backos, Olga Ilkayeva, Zhang G
Statins are a class of drug widely prescribed for the prevention of cardiovascular disease, with pleiotropic cellular effects. Statins inhibit HMG-CoA reductase (HMGCR), which converts the reactive HMG-CoA into mevalonate. Recent discoveries revealed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba58cadeee8d856bd7fa9fb243ceecd7
https://doi.org/10.21203/rs.3.rs-465103/v1
https://doi.org/10.21203/rs.3.rs-465103/v1
Autor:
Rachel Kadakia, Alan Kuang, Octavious Talbot, James R. Bain, Denise M. Scholtens, Sara K. O’Neal, William L. Lowe, Boyd E. Metzger, Lynn P. Lowe, Robert Stevens, Olga Ilkayeva, Michael Nodzenski, Christopher B. Newgard, Michael J. Muehlbauer
Publikováno v:
Diabetologia. 62:473-484
AIMS/HYPOTHESIS: We aimed to determine the association of maternal metabolites with newborn adiposity and hyperinsulinaemia in a multi-ethnic cohort of mother–newborn dyads. METHODS: Targeted and non-targeted metabolomics assays were performed on f
Autor:
Sanjeev Noel, J. Ricardo Carhuapoma, Peter A. Abdelmalik, Sarabdeep Singh, Ralph J Fuchs, Roger A. Johns, Robert Stevens, John Skinner
Publikováno v:
Journal of Critical Care. 44:323-330
Purpose Genetic deletions decreasing serum alpha-Klotho (alpha-KL) have been associated with rapid aging, multi-organ failure and increased mortality in experimental sepsis. We hypothesized that lower alpha-KL obtained at the onset of septic shock co
Autor:
Christopher B. Newgard, Michael Nodzenski, Anna C. Reisetter, Olga Ilkayeva, Saya Jacob, William L. Lowe, Boyd E. Metzger, James R. Bain, Denise M. Scholtens, Robert Stevens, Michael J. Muehlbauer, Lynn P. Lowe
Publikováno v:
Diabetes Care
OBJECTIVE We used targeted metabolomics in pregnant mothers to compare maternal metabolite associations with maternal BMI, glycemia, and insulin sensitivity. RESEARCH DESIGN AND METHODS Targeted metabolomic assays of clinical metabolites, amino acids
Autor:
Michael J. Muehlbauer, William L. Lowe, Christopher B. Newgard, Octavious Talbot, Alan Kuang, Lynn P. Lowe, Robert Stevens, Rachel Kadakia, Boyd E. Metzger, Olga Ilkayeva, James R. Bain, Denise M. Scholtens
Publikováno v:
Journal of the Endocrine Society
Newborn adiposity is associated with a higher risk of childhood obesity and earlier onset of co-morbid metabolic diseases such as type 2 diabetes mellitus. The cord blood metabolome is one early life marker that provides mechanistic insight into feta
Autor:
Andrew J. Goodwin, Nicholas J. Terrill, Robert Stevens, Simon King, Vlad Stolojan, S. Ravi P. Silva
By electrospinning poly(ethylene oxide) (PEO)-blended sodium dodecyl sulfate (SDS) functionalized carbon nanotube (CNT) solutions, we engineered single- and double-walled nanotubes into highly aligned arrays. CNT alignment was measured using electron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32dd38f7ee20982c0a6073cdbd474a0a
https://irep.ntu.ac.uk/id/eprint/34349/1/11764_Stevens.pdf
https://irep.ntu.ac.uk/id/eprint/34349/1/11764_Stevens.pdf
Autor:
Liping Wang, Tabitha George, Olga Ilkayeva, Jeff K. Trimmer, Jie An, Christopher B. Newgard, Robert W. McGarrah, Phillip J. White, Amanda L. Lapworth, Timothy P. Rolph, James R. Bain, Robert Stevens, Michael J. Muehlbauer, M. Julia Brosnan
Publikováno v:
Molecular Metabolism, Vol 5, Iss 7, Pp 538-551 (2016)
Molecular Metabolism
Molecular Metabolism
Objective A branched-chain amino acid (BCAA)-related metabolic signature is strongly associated with insulin resistance and predictive of incident diabetes and intervention outcomes. To better understand the role that this metabolite cluster plays in
Autor:
Peter Taylor, Robert Stevens
Publikováno v:
Pathology. 48:367-371
Actinotignum schaalii is a recognised cause of urinary tract infection. Following a case of urosepsis, 20 isolates of A. schaalii were collected over an initial 18 month period from urine and blood culture. An additional 25 isolates were collected ov
Autor:
Michael Nodzenski, Anna C. Reisetter, Olga Ilkayeva, Lynn P. Lowe, Michael J. Muehlbauer, William L. Lowe, Boyd E. Metzger, Robert Stevens, James R. Bain, Denise M. Scholtens, Christopher B. Newgard
Publikováno v:
Diabetes
Maternal metabolites and metabolic networks underlying associations between maternal glucose during pregnancy and newborn birth weight and adiposity demand fuller characterization. We performed targeted and nontargeted gas chromatography/mass spectro
Autor:
C. Lawrence Kien, Emily K. Tarleton, David B. Ebenstein, Karen I. Crain, Naomi K. Fukagawa, Deborah M. Muoio, Matthew E. Poynter, Robert Stevens, Dwight E. Matthews, Timothy R. Koves, Janice Y. Bunn
Publikováno v:
Journal of Lipid Research. 56:1795-1807
Palmitic acid (PA) is associated with higher blood concentrations of medium-chain acylcarnitines (MCACs), and we hypothesized that PA may inhibit progression of FA β-oxidation. Using a cross-over design, 17 adults were fed high PA (HPA) and low PA/h