Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nancy Lewis"'
Publikováno v:
Glycobiology. 27:450-456
Expanded access to DNA sequencing now fosters ready detection of site-specific human genome alterations whose actual significance requires in-depth functional study to rule in or out disease-causing mutations. This is a particular concern for genomic
Publikováno v:
The EMBO Journal. 24:4007-4017
Trypanosomatids are pathogenic protozoa that undergo a unique form of post-transcriptional RNA editing that inserts or deletes uridine nucleotides in many mitochondrial pre-mRNAs. Editing is catalyzed by a large multiprotein complex, the editosome. A
Autor:
Victor Brian Malave, Nancy Lewis Baenziger, Kuljeet Seehra, Yuh-Jiin I. Jong, Stephanie R. Ford
Publikováno v:
The FASEB Journal. 17:2319-2321
Increased Ser phosphorylation of tau microtubule-associated protein in the brain is an early feature of Alzheimer's disease (AD) that precedes progression of the disease to frank neuronal disruption. We demonstrate that bradykinin (BK) B2 receptor ac
Autor:
Yuh-Jiin I. Jong, R C Haddock, B. Wilhelm, L. R. Dalemar, Nancy Lewis Baenziger, Pat Mack, N. Perez, C. Lindberg
Publikováno v:
Journal of Biological Chemistry. 269:14892-14898
Human vascular endothelial cells and fibroblasts express a cell-surface degradative pathway for the multifunctional mediator histamine, which employs a receptor for the metabolic enzyme diamine oxidase (DAO) and results in cellular accumulation of th
Publikováno v:
Proceedings of the National Academy of Sciences. 90:10994-10998
We report the immunoaffinity isolation of bradykinin B2 receptors in a tyrosine-phosphorylated state from WI-38 human lung fibroblasts. We generated six monoclonal antibodies directed against B2 bradykinin receptor biologic activity mediating prostag
Publikováno v:
Journal of Biological Chemistry. 265:14395-14401
We have previously reported that human vascular endothelial cells and skin fibroblasts carry out degradation of [3H]histamine by a mechanism involving two successive enzymatic steps: imidazole ring tele-methylation by the cells' endogenous methyltran
Autor:
Nancy Lewis Ernst, Kenneth Stuart, Robert P. Igo, Reza Salavati, Bingbing Wang, Setareh S. Palazzo
Publikováno v:
RNA Interference, Editing, and Modification ISBN: 9781588292421
This chapter describes biochemical assays that have been used in analyzing RNA editing in kinetoplastid mitochondria and to characterize the general mechanism of editing by the editosome. Studies using these assays have shown that the characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5355c1aeb14ba92c3cdd60ca48c311a2
https://doi.org/10.1385/1-59259-775-0:251
https://doi.org/10.1385/1-59259-775-0:251
Autor:
Reza Salavati, David S. Weston, Nancy Lewis Ernst, Kenneth Stuart, Aswini K. Panigrahi, Robert P. Igo
Publikováno v:
Eukaryotic cell. 1(1)
Editing of mitochondrial mRNAs in kinetoplastid protozoa occurs by a series of enzymatic steps that insert and delete uridylates (U's) as specified by guide RNAs (gRNAs). The characteristics of the 3" exonuclease activity that removes the U's followi
Publikováno v:
Immunopharmacology. 33(1-3)
Human lung fibroblasts represent important targets for the biologic activities of bradykinin (BK). We have identified multiple mechanisms in these cells which may extend their potential for BK receptor responsiveness, particularly with regard to gene
Autor:
Sonia Castillo, Murray A. Raskind, Jeffrey B. Halter, Richard C. Veith, E. Alexandra Ashleigh, Enrique C. Villacres, M. Michele Murburg, Robert F. Barnes, Oscar A. Linares, Nancy Lewis, Elaine R. Peskind, Marcella Pascualy
Publikováno v:
Archives of General Psychiatry. 51:411
Background: To determine whether elevations of plasma norepinephrine (NE) in major depression represent increased sympathetic nervous system (SNS) activity and to assess the effects of desipramine hydrochloride on sympathetic function. Methods: SNS a