Zobrazeno 81 - 90
of 96
pro vyhledávání: '"Margery A. Connelly"'
Publikováno v:
Biochimica et biophysica acta. 1771(7)
High density lipoproteins (HDL) are protective against cardiovascular disease due to their important role in the reverse cholesterol transport (RCT) pathway. The selective transfer of cholesteryl ester (CE) from the HDL core to cells, the last step i
Autor:
Margery A. Connelly, David L. Silver, Yves L. Marcel, Philip W. Shaul, Margarita de la Llera-Moya, Ivan S. Yuhanna, Chatchawin Assanasen, Divya Seetharam, David L. Williams, Chieko Mineo
The binding of HDL to scavenger receptor-BI (SR-BI) mediates cholesterol movement. HDL also induces multiple cellular signals, which in endothelium occur through SR-BI and converge to activate eNOS. To determine the molecular basis of a signaling eve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef31caa17a0f573f035dda8241a8215
https://europepmc.org/articles/PMC1069105/
https://europepmc.org/articles/PMC1069105/
Autor:
Margery A. Connelly, David L. Williams
Publikováno v:
Endocrine research. 30(4)
Scavenger receptor class B, type I (SR-BI) is the receptor for high density lipoprotein (HDL) that mediates cellular uptake of HDL cholesteryl ester (CE) and is a major route for cholesterol delivery to steroidogenic pathways. SR-BI is localized in s
Autor:
David L. Williams, Saj Parathath, Nada A. Abumrad, Charles R. Iden, George H. Rothblat, Seth M. Klein, Margarita de la Llera-Moya, Margery A. Connelly, Robert Rieger
Publikováno v:
The Journal of biological chemistry. 279(40)
In mammalian cells scavenger receptor class B, type I (SR-BI), mediates the selective uptake of high density lipoprotein (HDL) cholesteryl ester into hepatic and steroidogenic cells. In addition, SR-BI has a variety of effects on plasma membrane prop
Autor:
David L. Williams, Margery A. Connelly, Michael C. Phillips, Wendy Akmentin, Yinan Peng, Sissel Lund-Katz
Receptor-mediated trafficking of cholesterol between lipoproteins and cells is a fundamental biological process at the organismal and cellular levels. In contrast to the well-studied pathway of LDL receptor-mediated endocytosis, little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c5ee56bb5ab34e097c4120383897c9
https://europepmc.org/articles/PMC307555/
https://europepmc.org/articles/PMC307555/
Autor:
Margarita de la Llera-Moya, George H. Rothblat, Yinan Peng, David L. Williams, Margery A. Connelly, Denise Drazul-Schrader
Publikováno v:
The Journal of biological chemistry. 278(28)
Scavenger receptor class B, type I (SR-BI) shows a variety of effects on cellular cholesterol metabolism, including increased selective uptake of high density lipoprotein (HDL) cholesteryl ester, stimulation of free cholesterol (FC) efflux from cells
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 2, Pp 331-341 (2003)
We have examined the metabolic fate of HDL cholesteryl ester (CE) delivered to cells expressing scavenger receptor class B type I (SR-BI). Comparison of SR-BI with a related class B scavenger receptor, CD36, showed a greater uptake and a more rapid a
Autor:
Patricia G. Yancey, Margery A. Connelly, George H. Rothblat, William J. Johnson, Margarita de la Llera-Moya, Seth M. Klein, David L. Williams, Pascale Monzo, Snehasikta Swarnakar
Publikováno v:
The Journal of biological chemistry. 275(47)
The role of high density lipoprotein (HDL) phospholipid in scavenger receptor BI (SR-BI)-mediated free cholesterol flux was examined by manipulating HDL(3) phosphatidylcholine and sphingomyelin content. Both phosphatidylcholine and sphingomyelin enri
Publikováno v:
Current opinion in clinical nutrition and metabolic care. 3(4)
Lipophilic molecules can passively diffuse across cell membranes, a process that is driven by the concentration gradient, by availability of acceptors to facilitate desorption from the bilayer, and by cellular metabolism. However, evidence has accumu
Autor:
Michael C. Phillips, Sissel Lund-Katz, David L. Williams, Gattadahalli M. Anantharamaiah, Margarita de la Llera-Moya, Salman Azhar, Stephen T. Thuahnai, Margery A. Connelly
Publikováno v:
The Journal of biological chemistry. 275(25)
Scavenger receptor, class B, type I (SR-BI) mediates the selective uptake of high density lipoprotein (HDL) cholesteryl ester without the uptake and degradation of the particle. In transfected cells SR-BI recognizes HDL, low density lipoprotein (LDL)