Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Manabu Mukai"'
Autor:
Ayumi Tsukada, Ken Takata, Jun Aikawa, Dai Iwase, Manabu Mukai, Yui Uekusa, Yukie Metoki, Gen Inoue, Masayuki Miyagi, Masashi Takaso, Kentaro Uchida
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 877 (2024)
Diabetes mellitus (DM) has been suggested as a potential risk factor for knee osteoarthritis (KOA), and its underlying mechanisms remain unclear. The infrapatellar fat pad (IPFP) contributes to OA through inflammatory mediator secretion. Mast cells
Externí odkaz:
https://doaj.org/article/9ac11c848c7f44c9abcc9f9513906c91
Autor:
Ayumi Tsukada, Ken Takata, Shotaro Takano, Yoshihisa Ohashi, Manabu Mukai, Jun Aikawa, Dai Iwase, Gen Inoue, Masashi Takaso, Kentaro Uchida
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11237 (2022)
Obesity is a risk factor for knee osteoarthritis (KOA). Neuromedin U (NMU) and NMU receptors (NMUR1 and NMUR2) are associated with obesity-related disorders and found in mast cells (MCs), which are elevated in osteoarthritis. However, NMU/NMUR expres
Externí odkaz:
https://doaj.org/article/0ff7060264cd482d9b69a2a773f11d9f
Autor:
Masashi Takaso, Manabu Mukai, Ken Sugo, Ken Urabe, Takehiko Nakajima, Ken Takata, Kentaro Uchida, Masanori Nakasu
Publikováno v:
Bio-Medical Materials and Engineering. 33:41-50
BACKGROUND: Periprosthetic joint infection is a major complication of total joint arthroplasty, with treatment requiring a two-stage exchange procedure and 6 weeks of systemic antibiotics. However, depending on the infection site, intravenous deliver
Autor:
Jun Aikawa, Masashi Takaso, Hiroyuki Sekiguchi, Gen Inoue, Masayuki Miyagi, Shotaro Takano, Ken Takata, Manabu Mukai, Dai Iwase, Kentaro Uchida
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Ken Takata, Kentaro Uchida, Shotaro Takano, Manabu Mukai, Gen Inoue, Hiroyuki Sekiguchi, Jun Aikawa, Masayuki Miyagi, Dai Iwase, Masashi Takaso Department of Orthopedic Surgery, Kitasato University School of Medicine, Sagamihara City, Kanagawa, 252-0
Autor:
Shotaro Takano, Shintaro Shoji, Masashi Takaso, Manabu Mukai, Makoto Itakura, Jun Aikawa, Hiroyuki Sekiguchi, Dai Iwase, Kentaro Uchida, Gen Inoue
Publikováno v:
BioMed Research International, Vol 2019 (2019)
Background. Previous studies suggest the presence of an association of vascular endothelial growth factor (VEGF) with osteoarthritis (OA) severity and pain in patients with knee OA. VEGF expression in human synovial fibroblasts (SFs) is induced by tr
Autor:
Manabu Mukai, Kentaro Uchida, Tadashi Okubo, Shotaro Takano, Toshihide Matsumoto, Masashi Satoh, Gen Inoue, Masashi Takaso
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Frontiers in Medicine
Frontiers in Medicine
Background:Bone marrow-derived monocytes/macrophages are recruited into synovial tissue, where they contribute to synovial inflammation in osteoarthritis through inflammatory cytokine production. Recent studies have suggested that V-Set and transmemb
Autor:
Toshihide Matsumoto, Gen Inoue, Dai Iwase, Kentaro Uchida, Jun Aikawa, Masayuki Miyagi, Shotaro Takano, Manabu Mukai, Masashi Takaso
Publikováno v:
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-8 (2018)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders
Background Research suggests that vascular endothelial growth factor (VEGF) levels in the synovial fluid of knee osteoarthritis (KOA) patients are positively correlated with KOA severity. The relationship between synovial VEGF levels and pain in huma