Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Khalid M. El-Say"'
Publikováno v:
Nanomaterials, Vol 12, Iss 22, p 3966 (2022)
The development of an oral anti-diabetic medication characterized by enhanced hypoglycemic activity is in high demand. The goal was to study the hypoglycemic activity and pancreatic histopathology after the black-seed-based self-nanoemulsifying drug
Externí odkaz:
https://doaj.org/article/22ef2cd201e74dbaa57b61c619b8f00b
Publikováno v:
ACS Omega, Vol 5, Iss 25, Pp 15476-15486 (2020)
Externí odkaz:
https://doaj.org/article/c74a8801f88a47bda1acd37a8f8fba6d
Publikováno v:
ACS Omega, Vol 5, Iss 25, Pp 15476-15486 (2020)
ACS Omega
ACS Omega
Fluvastatin (FLV) is a statin family member that may play a role in modulating a variety of medical disorders such as atherosclerosis and breast cancer. The present study addresses the ability of FLV to modulate the cellular immune response and provi
Publikováno v:
Drug Design, Development and Therapy. 13:4035-4051
Background Injectable in situ gel (ISG) systems suffer from high initial drug release that may result in toxic effects. Objective This work aimed to develop an injectable sustained release rosuvastatin (RSV) ISG formulation with minimum initial drug
Autor:
Nabil A. Alhakamy, Khalid M. El-Say, Waleed Y. Rizg, Gamal A. Mohamed, Hanadi A Alotaibi, Tarek A. Ahmed, Fathy I. Abd-Allah, Ahmed S. Zidan, Fuad H Alnadwi, Hossam H. Tayeb, Raed Felimban
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1733, p 1733 (2021)
Volume 13
Issue 10
Pharmaceutics, Vol 13, Iss 1733, p 1733 (2021)
Volume 13
Issue 10
This work aimed to develop a three-dimensional printed (3DP) tablet containing glimepiride (GLMP) and/or rosuvastatin (RSV) for treatment of dyslipidemia in patients with diabetes. Curcumin oil was extracted from the dried rhizomes of Curcuma longa a
Publikováno v:
Pharmaceutics, Vol 13, Iss 739, p 739 (2021)
Pharmaceutics
Volume 13
Issue 5
Pharmaceutics
Volume 13
Issue 5
To avoid the first-pass metabolism of avanafil (AVA) and its altered absorption in the presence of food after oral administration, this study aimed to investigate the potential of TPGS-based mixed micelle (MM)-loaded film for transdermal delivery and
Publikováno v:
International Journal of Nanomedicine. 14:5555-5567
Background: Vinpocetine (VPN) is a synthetic derivative of the Vinca minor alkaloids. The drug is characterized by a short half-life, limited water solubility and high hepatic first-pass effect. The objective was to develop different lipid-based nano
Publikováno v:
Drug Development and Industrial Pharmacy. 45:1130-1139
Objective: Control the release and enhance the bioavailability of chitosan-doxazosin mesylate nanoparticles (DM-NPs). Significance: Improve DM bioavailability for the treatment of benign prostatic hyperplasia and hypertension. Methods: Plackett-Burma
Publikováno v:
International Journal of Nanomedicine
Osama AA Ahmed,1,2 Khalid M El-Say,1,3 Bader M Aljaeid,1 Shaimaa M Badr-Eldin,1,4 Tarek A Ahmed1,3 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Pharmaceutics and Industr
Autor:
Khalid M. El-Say, Mahmoud A. Elfaky, Bader M Aljaeid, Usama A. Fahmy, Ohood A. Al-Shareef, Hibah M. Aldawsari
Publikováno v:
Journal of Drug Delivery Science and Technology. 46:7-13
Self-nanoemulsifying delivery systems (SNEDs) are one of the most important approaches for increasing the solubilization and absorption of a drug. This study aimed to develop a system using fluvastatin (FLV) in SNEDs with minimum globule size to enha