Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jennifer, Baker"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6336 (2021)
Background: Preclinical drug development studies rarely consider the impact of a candidate drug on established metastatic disease. This may explain why agents that are successful in subcutaneous and even orthotopic preclinical models often fail to de
Externí odkaz:
https://doaj.org/article/a8a6a59eb14a48ddad7c24e7941eb735
Autor:
Arthur Connell, Sanjay Ghosh, Robert J. Hobbs, Leo Furnell, Cameron Pleydell-Pearce, Jennifer Baker, Matthew L. Davies, Rosie Anthony, Peter J. Holliman, Eurig W. Jones
Publikováno v:
Chemical communications (Cambridge, England). 52(23)
We report a solvent-free approach to synthesizing organolead\ud perovskites by using solid state reactions to coat perovskite crystals\ud onto Al2O3 or TiO2 nanoparticles followed by addition of terpineol\ud affording perovskite inks. We have bar cas
Publikováno v:
Skin appendage disorders. 1(3)
Autor:
Patrick F. Smith, Petrie M. Rainey, Abayomi B. Ogundele, David E. Moody, Patricia Pade, Gene D. Morse, Anika Alvanzo, Peter Jatlow, Gerald Friedland, Jennifer Baker, Elinore F. McCance-Katz
Publikováno v:
Clinical Infectious Diseases. 43:S224-S234
This study examined drug interactions between buprenorphine, an opioid partial agonist medication used in the treatment of opioid dependence, and the nonnucleoside reverse-transcriptase inhibitors (NNRTIs) efavirenz (EFV) and delavirdine (DLV). Opioi
Autor:
Jennifer Baker, Stephen Day, Deborah A. Nicoll-Griffith, Kevin P. Bateman, Tammy LeRiche, Nathalie Chauret, Mark Wilke, Marc Ouellet, Carmai Seto, Justin Lee
Publikováno v:
Chemical Research in Toxicology. 17:1356-1361
Protein covalent labeling can be an undesirable property of compounds being studied in drug discovery programs. Identifying such compounds relies on the use of radiolabeled material, which requires an investment in time and resources not typically ex
Publikováno v:
Journal of Clinical Laboratory Analysis. 18:159-164
The degradation of a biological product follows a specific pattern that depends on the kinetics of the chemical reaction. For most biological and pharmaceutical products, accelerated stability tests are preferred to establish shelf life. We describe
Autor:
Huawei Qiu, Xiaoying Jin, Debra A. Barngrover, Karen Lee, Laura Geagan, Tim Edmunds, Lorraine Copertino, Laura Andrews, Kate Zhang, Keirsten Seiger, John M. McPherson, Jennifer Baker-Malcolm
Publikováno v:
Glycobiology. 13:305-313
Fabry disease is a lysosomal storage disease arising from deficiency of the enzyme alpha-galactosidase A. Two recombinant protein therapeutics, Fabrazyme (agalsidase beta) and Replagal (agalsidase alfa), have been approved in Europe as enzyme replace
Autor:
Trystan Watson, Geraint Williams, Wing C. Tsoi, Ronald N. Clark, David T. Gethin, Harrison Ka Hin Lee, Carys Worsley, David A. Worsley, Jennifer Baker
Publikováno v:
Advanced Engineering Materials. 19:1600652
Graphene nanoparticles have been subject to intensive investigation as a replacement for platinum as the catalyst in dye sensitized solar cells (DSCs), but few of these investigations examine the application for flexible cells with deposition process
Publikováno v:
Platelets. 12:333-342
The intracellular pH of human platelets is affected by external pH and by the addition of metabolic substrates and analogues. Acetate and propionate decrease pH in a rapid concentration-dependent manner, whereas glucose decreases the internal pH at a
Autor:
Massimo Pignatelli, Jennifer Baker, Richard S. Daly, Moganaden Moorghen, Andrea Buda, Nahida A. Banu
Publikováno v:
Cell communicationadhesion. 18(1-2)
Cyclooxygenase (COX)-2 is a key molecular target of colon cancer prevention. However, the mechanisms by which COX-2 inhibitors confer protective effects against tumour development are not completely understood. The aim of this study was to elucidate