Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jan Trnka"'
Metabolic flux investigations of cells and tissue samples are a rapidly advancing tool in diverse research areas. Reliable methods of data normalization are crucial for an adequate interpretation of results and to avoid a misinterpretation of experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3aa35edb345ef381647ea89e0982922
https://doi.org/10.1101/2021.03.19.436150
https://doi.org/10.1101/2021.03.19.436150
Autor:
Tomáš Bílý, Kafkova A, Jana Nebesářová, Julien Prudent, Jan Trnka, Marie Vancová, Trčka F, Lisa Tilokani, Šrámková
Mitochondria represent an attractive drug target in the treatment of many diseases. One of the most commonly used approaches to deliver therapeutics specifically into mitochondria is their conjugation to the triphenylphosphonium (TPP) moiety. While t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18ca7c793e093bf9b3c0f11a790d65c4
https://doi.org/10.1101/2021.03.09.434520
https://doi.org/10.1101/2021.03.09.434520
Publikováno v:
International Agrophysics. 32:421-428
For the purpose of this paper, sugar beet roots were loaded by creating the impact of aluminium bars falling from different heights. The time history of the force at the contact between the sugar beet root and the bar was measured. The response of th
Adipogenesis, lipogenesis and lipolysis is stimulated by mild but not severe hypoxia in 3T3-L1 cells
Autor:
Michal Koc, Jan Pala, Jan Polak, Martin Weiszenstein, Jan Trnka, Sumeet Gulati, Katerina Westlake, Moustafa Elkalaf, Andrea Plihalova, Antonin Prochazka, Martina Musutova
Publikováno v:
Biochemical and Biophysical Research Communications. 478:727-732
In-vitro investigation of the effects of hypoxia is limited by physical laws of gas diffusion and cellular O2 consumption, making prolonged exposures to stable O2 concentrations impossible. Using a gas-permeable cultureware, chronic effects of mild a
Autor:
Petr Vaňhara, Sebastiano Masuri, Franziska Walter, Josef Havel, Lukáš Moráň, Jochen H. M. Prehn, Moustafa Elkalaf, Kateřina Vašíčková, Jan Trnka, Tiziana Pivetta
Publikováno v:
Metallomics : integrated biometal science. 11(9)
There is an ongoing need for the development of new cancer therapeutics that combine high cytotoxic efficiency with low side effects, and also override resistance to the first-line chemotherapeutics. Copper(ii)–phenanthroline complexes are promisin
Autor:
Moustafa Elkalaf, Jan Kovar, Minh Duc Trinh, Jan Rambousek, Michal Koc, Kamila Balušíková, Beatriz Volckaert, Martin Kalous, Jan Polak, Stanislav Povysil, Jan Trnka, Natálie Klubíčková, Martina Musutova, František Duška
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 9 (2018)
Frontiers in Endocrinology, Vol 9 (2018)
Metabolic impairments associated with obstructive sleep apnea syndrome (OSA) are linked to tissue hypoxia, however, the explanatory molecular and endocrine mechanisms remain unknown. Using gas-permeable cultureware, we studied the chronic effects of
Publikováno v:
Journal of Food Engineering. 166:86-94
The eggs of wild-type European-originated quails were stored for 1, 2, 3, 4, 6, 8, 10, 12, 14, and 16 weeks at constant temperature 4 °C. The three groups of parameters describing the egg quality were obtained. First of all the egg quality parameter
Publikováno v:
Cellular Physiology and Biochemistry, Vol 33, Iss 5, Pp 1439-1451 (2014)
Background/Aims: Deleterious effects of saturated fatty acids in skeletal muscle cells are well known but their impact on mitochondrial respiration has not been well studied. Mitochondrial oxidative damage has been implicated to play a role in their
Autor:
Vladimir Stich, Michal Anděl, J Tůmová, Jan Gojda, Jan Trnka, Moustafa Elkalaf, Eva Krauzová, Jana Potockova, Petr Waldauf, Radka Straková, Martin Jaček, Lenka Rossmeislová, Petr Tůma
Publikováno v:
European journal of clinical nutrition. 71(5)
Branched chain amino acids (BCAA) are among nutrients strongly linked with insulin sensitivity (IS) measures. We investigated the effects of a chronic increase of BCAA intake on IS in two groups of healthy subjects differing in their basal consumptio
Autor:
Kateřina Jiroutková, Jan Gojda, Adéla Krajčová, Jakub Žiak, Martin Kalous, Jan Trnka, František Duška, Michal Fric, Valér Džupa, Jana Tůmová
Publikováno v:
JPEN. Journal of parenteral and enteral nutrition. 41(7)
BACKGROUND Functional mitochondria in skeletal muscle of patients with protracted critical illness and intensive care unit-acquired weakness are depleted, but remaining mitochondria have increased functional capacities of respiratory complexes II and