Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Hiroaki Konishi"'
Autor:
Eiji Nakata, Khongorzul Gerelbaatar, Mashal Asif, Hiroaki Konishi, Yuya Shibano, Peng Lin, Takashi Morii
Publikováno v:
Chemistry, Vol 5, Iss 3, Pp 1832-1842 (2023)
The desirable properties of the sophisticated fluorescent pH probe are ratiometric detection properties and a wide detection range. In this study, three types of fluorophores with different fluorescence properties were assembled on a DNA origami nano
Externí odkaz:
https://doaj.org/article/eed6f00e10d847e49239e9b5fec00ec6
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12303 (2021)
MicroRNAs (miRNAs) are single-stranded short-chain RNAs that are endogenously expressed in vertebrates; they are considered the fine-tuners of cellular protein expression that act by modifying mRNA translation. miRNAs control tissue development and d
Externí odkaz:
https://doaj.org/article/7c71271d135449329031dda9ddc863a8
Autor:
Keitaro Takahashi, Mikihiro Fujiya, Hiroaki Konishi, Yuki Murakami, Takuya Iwama, Takahiro Sasaki, Takehito Kunogi, Aki Sakatani, Katsuyoshi Ando, Nobuhiro Ueno, Shin Kashima, Kentaro Moriichi, Hiroki Tanabe, Toshikatsu Okumura
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4514 (2020)
The oncogenic properties of heterogeneous nuclear ribonucleoprotein H1 (hnRNP H1) have been reported, although the tumor-promoting mechanism remains unclear. We herein report the mechanism underlying colorectal cancer cell progression mediated by hnR
Externí odkaz:
https://doaj.org/article/af1a9c26b1e74a84a0ae43a7c191ecb8
Publikováno v:
Cellular & Molecular Biology Letters, Vol 26, Iss 1, Pp 1-11 (2021)
Cellular & Molecular Biology Letters
Cellular & Molecular Biology Letters
Background In mammals, there are two subtypes of Grb2-associated regulator of Erk/MAPK (GAREM), an adaptor protein that functions downstream of the cell growth factor receptor. GAREM1 is ubiquitously expressed, whereas GAREM2 is mainly expressed in t
Autor:
Keisuke Taniguchi, Hiroaki Konishi, Hiroyuki Takahashi, Fukiko Nishisaka, Momomi Tsugane, Yoshiyuki Shishido, Akiko Yoshinaga, Akira Asai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Signal transducer and activator of transcription 3 (STAT3) plays a critical role in regulating cell growth, survival, and metastasis. STAT3 signaling is constitutively activated in various types of hematologic or solid malignancies. YHO-1701 has been
Autor:
Shin Kashima, Mikihiro Fujiya, Shuhei Takauji, Hiroaki Konishi, Toshikatsu Okumura, Hiroki Sato, Nobuhiro Ueno, Shotaro Isozaki, Hiroki Tanaka, Kentaro Moriichi, Yusuke Mizukami
Publikováno v:
Digestive Diseases and Sciences. 66:3872-3884
We previously showed that Lactobacillus brevis-derived polyphosphate (poly P) exerts a curative effect on intestinal inflammation. However, whether or not poly P improves the inflammation and injury of distant organs remains unclear. We aimed to inve
Autor:
Yu Kimura, Teruyuki Kondo, Natsuki Matsumoto, Hisatsugu Yamada, Aoi Son, Hiroaki Konishi, Tetsuya Matsuda, Hirohiko Imai, Yasuhiro Aoyama, Takanori Komaki
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Three-dimensional (3D) representation of a tumor with respect to its size, shape, location, and boundaries is still a challenge in photoacoustic (PA) imaging using artificial contrast agents as probes. We carried out PA imaging of tumors in mice usin
Autor:
Takuya Iwama, Mikihiro Fujiya, Takuma Goto, Akemi Kita, Naoki Ogawa, Shuhei Takauji, Masami Ijiri, Toshikatsu Okumura, Katsuyoshi Ando, Hiroki Tanaka, Aki Sakatani, Shin Kashima, Yuki Murakami, Hiroaki Konishi, Nobuhiro Ueno
Publikováno v:
International Journal of Oncology
Pancreatic cancer is associated with a poor prognosis due to challenges in early detection, severe progression of the primary tumor, metastatic lesions, and resistance to antitumor agents. However, previous studies have indicated a relationship betwe
Publikováno v:
ChemistrySelect. 5:6237-6241
Publikováno v:
ChemistrySelect. 5:4943-4946