Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Herbert J. Zeh"'
Autor:
Enyong Dai, Leng Han, Yangchun Xie, Jiao Liu, Rui Kang, Herbert J. Zeh, Daolin Tang, Lulu Bai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Ferroptosis is a more recently recognized form of cell death that relies on iron-mediated oxidative damage. Here, we evaluate the impact of high-iron diets or depletion of Gpx4, an antioxidant enzyme reported as an important ferroptosis suppressor, i
Autor:
Jun Huang, Ke Liu, Guido Kroemer, Changfeng Li, Borong Zou, Daolin Tang, Rui Kang, Jiao Liu, Herbert J. Zeh
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2022, 13 (2), pp.483-500. ⟨10.1016/j.jcmgh.2021.09.008⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 483-500 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2022, 13 (2), pp.483-500. ⟨10.1016/j.jcmgh.2021.09.008⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 483-500 (2022)
Background & Aims Pancreatitis is characterized by acinar cell death and persistent inflammation. Ferroptosis is a type of lipid peroxidation-dependent necrosis, which is negatively regulated by glutathione peroxidase 4. We studied how trypsin, a ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2672294190e99060699bb76afc1e37a6
https://hal.sorbonne-universite.fr/hal-03549632/file/1-s2.0-S2352345X2100196X-main.pdf
https://hal.sorbonne-universite.fr/hal-03549632/file/1-s2.0-S2352345X2100196X-main.pdf
Autor:
Herbert J. Zeh, Ulka Sachdev, Sebastian Vogel, Xiangdong Cui, Pranav Murthy, Michael T. Lotze
Publikováno v:
Biochemical and Biophysical Research Communications. 508:614-619
Platelets play a critical role in the pathophysiology of peripheral arterial disease (PAD). The mechanisms by which muscle ischemia regulates aggregation of platelets are poorly understood. We have recently identified the Nod-like receptor nucleotide
Autor:
Xinxin Song, Xin Chen, Feimei Kuang, Daolin Tang, Herbert J. Zeh, Jiao Liu, Rui Kang, Guido Kroemer, Yangchun Xie
Publikováno v:
Cell Reports, Vol 34, Iss 8, Pp 108767-(2021)
Cell Reports
Cell Reports, Elsevier Inc, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
Cell Reports, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
Cell Reports
Cell Reports, Elsevier Inc, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
Cell Reports, 2021, 34 (8), pp.108767. ⟨10.1016/j.celrep.2021.108767⟩
International audience; Although induction of ferroptosis, an iron-dependent form of non-apoptotic cell death, has emerged as an anticancer strategy, the metabolic basis of ferroptotic death remains poorly elucidated. Here, we show that glucose deter
Autor:
Daolin Tang, Ling Zeng, Daniel J. Klionsky, Borong Zhou, Shan Zhu, Jianxin Jiang, Timothy R. Billiar, Guido Kroemer, Haichao Wang, Jiao Liu, Herbert J. Zeh, Rui Kang
Publikováno v:
Autophagy
Sepsis is the most common cause of death for patients in intensive care worldwide due to a dysregulated host response to infection. Here, we investigate the role of sequestosome-1 (SQSTM1/p62), an autophagy receptor that functions as a regulator of i
Autor:
Michael T. Lotze, Daolin Tang, Jiao Liu, Herbert J. Zeh, Guido Kroemer, Runliu Wu, Zexian Liu, Changfeng Li, Pan Chen, Jin Huang, Rui Kang, Ke Liu, Qiu Peng, Borong Zhou
Publikováno v:
Gut. 70(5)
ObjectiveAdaptive immune resistance mediated by the cytokine interferon gamma (IFNG) still constitutes a major problem in cancer immunotherapy. We develop strategies for overcoming IFNG-mediated adaptive immune resistance in pancreatic ductal adenoca
Autor:
Lingyi Sun, Michael T. Lotze, Pengcheng Wang, Guido Kroemer, Yangchun Xie, Dexing Zeng, Timothy R. Billiar, David L. Bartlett, Xinxin Song, Shan Zhu, Jiao Liu, Rui Kang, Xiaochao Ma, Herbert J. Zeh, Daolin Tang
Publikováno v:
Gastroenterology. 154:1480-1493
Background & Aims Maintenance of acid–base homeostasis is required for normal physiology, metabolism, and development. It is not clear how cell death is activated in response to changes in pH. We performed a screen to identify agents that induce ce
Publikováno v:
Autophagy. 14:2173-2175
Ferroptosis is a form of regulated cell death triggered by lipid peroxidation after inhibition of the cystine/glutamate antiporter system X(c)(−). However, key regulators of system X(c)(−) activity in ferroptosis remain undefined. Here, we show t
Autor:
Qiuhong Zhang, Shan Zhu, Michael T. Lotze, Xiaofang Sun, Rui Kang, Daolin Tang, Herbert J. Zeh
Publikováno v:
Cancer Research. 77:2064-2077
Ferroptosis is a form of regulated cell death driven by oxidative injury promoting lipid peroxidation, although detailed molecular regulators are largely unknown. Here, we show that heatshock 70-kDa protein 5 (HSPA5) negatively regulates ferroptosis
Autor:
Yixiang Zhen, Xiao Zhong, Ruochan Chen, Timothy R. Billiar, Xue Gong Fan, Haichao Wang, Daolin Tang, Yongmin Fu, Yan Huang, Pinhua Pan, Yangchun Xie, Rui Kang, Herbert J. Zeh, David L. Bartlett, Michael T. Lotze
Publikováno v:
Oncotarget
// Ruochan Chen 1, 2 , Yangchun Xie 2 , Xiao Zhong 1 , Yongmin Fu 1 , Yan Huang 1 , Yixiang Zhen 1 , Pinhua Pan 3 , Haichao Wang 4 , David L. Bartlett 2 , Timothy R. Billiar 2 , Michael T. Lotze 2 , Herbert J. Zeh, III 2 , Xue-Gong Fan 1 , Daolin Tan