Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Gary M. Mawe"'
Autor:
John R. Ussher, Dianne Matthews, Grace B. Flock, Gary M. Mawe, Brigitte Lavoie, Bernardo Yusta, Daniel J. Drucker
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 6, Pp 503-511 (2017)
Molecular Metabolism, Vol 6, Iss 6, Pp 503-511 (2017)
Objective Glucagon-like peptides (GLPs) are secreted from enteroendocrine cells in response to nutrients and bile acids and control metabolism via actions on structurally-related yet distinct G protein coupled receptors. GLP-1 regulates gut motility,
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783319666518
The processes of bone growth and turnover are tightly regulated by the actions of various signaling molecules, including hormones, growth factors, and cytokines. Imbalances in these processes can lead to skeletal disorders such as osteoporosis or hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7dc973f3c78ed3847364650a8c65238
https://doi.org/10.1007/978-3-319-66653-2_3
https://doi.org/10.1007/978-3-319-66653-2_3
Autor:
Gary M. Mawe, Savannah Patterson, Onesmo B. Balemba, Thomas Hofmann, John McMillan, Sofie Lösch, Timo D. Stark
Publikováno v:
Journal of Smooth Muscle Research. 50:48-65
Garcinia buchananii Baker stem bark extract (GBB) is a traditional medication of diarrhea and dysentery in sub-Saharan Africa. It is believed that GBB causes gastrointestinal smooth muscle relaxation. The aim of this study was to determine whether GB
Publikováno v:
The Journal of Physiology. 591:3725-3737
Colitis, induced by trinitrobenzene sulfonic acid (TNBS) in guinea pig, leads to decreased purinergic neuromuscular transmission resulting in a reduction in inhibitory junction potentials (IJPs) in colonic circular muscle. We explored possible mechan
Autor:
Rebecca Wilcox, E. A. Zane, Gary M. Mawe, Mark T. Nelson, Monika R. Leonard, Brigitte Lavoie, Onesmo B. Balemba, Martin C. Carey, Aaron C. Bartoo, Bernhard Nausch
Publikováno v:
Neurogastroenterology & Motility. 24:e313-e324
BACKGROUND; Decreased gallbladder smooth muscle (GBSM) contractility is a hallmark of cholesterol gallstone disease, but the interrelationship between lithogenicity, biliary stasis, and inflammation are poorly understood. We studied a mouse model of
Autor:
Ken Mackie, Gary M. Mawe, Keith A. Sharkey, Martin Storr, Ian M. Hons, Beat Lutz, Quentin J. Pittman
Publikováno v:
Neurogastroenterology & Motility. 24:e113-e124
The myenteric and submucosal plexuses of the enteric nervous system (ENS) exist as interconnected integrative nerve networks within the wall of the gastrointestinal (GI) tract. Activity of the ENS is responsible for the control of the digestive and p
Autor:
Brigitte Lavoie, Onesmo B. Balemba, Cody B. Godfrey, Gary M. Mawe, Mark T. Nelson, Conall A. Watson, Galya Vassileva, Carlos U. Corvera
Publikováno v:
The Journal of Physiology. 588:3295-3305
Hydrophobic bile salts are thought to contribute to the disruption of gallbladder smooth muscle (GBSM) function that occurs in gallstone disease, but their mechanism of action is unknown. The current study was undertaken to determine how hydrophobic
Autor:
Gary M. Mawe, Yogesh Bhattarai, Chloe M. Stenkamp-Strahm, Onesmo B. Balemba, Mellau S.B. Lesakit
Publikováno v:
Neurogastroenterology & Motility. 22:1332-1339
Background Garcinia buchananii bark extract is a traditional African remedy for diarrhea, dysentery, abdominal discomfort, and pain. We investigated the mechanisms and efficacy of this extract using the guinea pig distal colon model of gastrointestin
Autor:
Derek S. Strong, Keith A. Sharkey, Jill M. Hoffman, Jane Roberts, Gary M. Mawe, Carson F. Cornbrooks
Publikováno v:
The Journal of Physiology. 588:847-859
This study was undertaken to investigate neuromuscular transmission in regions of the inflamed colon in which motility is disrupted. Propulsive motility was evaluated in segments of control guinea pigs and those treated 6 days previously with trinitr
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 292:G482-G491
Functional changes induced by inflammation persist following recovery from the inflammatory response, but the mechanisms underlying these changes are not well understood. Our aim was to investigate whether the excitability and synaptic properties of