Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Donghwa Kim"'
Autor:
Jeong Do Yoo, Eunji Park, Gyungmin Lee, Myung Kil Ahn, Donghwa Kim, Seongyun Seo, Huy Kang Kim
Publikováno v:
Applied Sciences, Vol 10, Iss 6, p 2140 (2020)
As the scale of the system and network grows, IT infrastructure becomes more complex and hard to be managed. Many organizations have a serious problem to manage their system and network security. In addition, vulnerabilities of hardware and software
Externí odkaz:
https://doaj.org/article/88939f3e7e8446188cdfb48ba5c34c81
Autor:
Sang Kook Lee, Sanghee Kim, Kyoungsun Choi, Donghwa Kim, Jaeho Han, Sang Won Choi, Koung Li Kim, Wonhee Suh, Soongyu Choi, S. J. Seo, Jedo Oh, Jae-Hui Been, Wenzhe Jiang, Jihee Cho, Changmin Park
Publikováno v:
Journal of Medicinal Chemistry. 64:5535-5550
Diabetic retinopathy is the leading cause of blindness which is associated with excessive angiogenesis. Using the structure of wondonin marine natural products, we previously created a scaffold to develop a novel type of antiangiogenesis agent that p
Autor:
Feng Qin, Cai Yi Wang, Sang Kook Lee, Yan-Kui Zhu, Heng-Shan Wang, Gui-Yang Yao, Donghwa Kim, Dong Liang
Publikováno v:
The Journal of Organic Chemistry. 86:1462-1470
Nitidumpeptins A and B (1 and 2), two novel cyclic hexapeptides, were isolated from the herb Zanthoxylum nitidum var. tomentosum. Their planar structures were elucidated based on NMR and MS spectrometric analysis, and the absolute configurations were
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Bitter taste receptors (TAS2Rs) are recognized as being expressed on multiple cell types and organs, including human airway smooth muscle (HASM) cells, where agonists promote significant relaxation to constrictive stimuli. Thus, the
Autor:
Jeeyeon Lee, Sunghwa Kim, Hyeung-geun Park, Won Kyung Kim, Hwa-Jin Chung, Kyungkuk Jang, Donghwa Kim, Woong Sub Byun, Eun Seo Bae, Sunghyouk Park, Sang Kook Lee, Han Sun Kim, Hae Ju Han
Publikováno v:
Molecular Therapy: Oncolytics, Vol 15, Iss, Pp 140-152 (2019)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Triple-negative breast cancer (TNBC) is the most intractable cancer in women with a high risk of metastasis. While hyper-methylation of histone H3 catalyzed by disruptor of telomeric silencing 1-like (DOT1L), a specific methyltransferase for histone
Autor:
Sang Kook Lee, Ri Zhen Huang, Yan Kui Zhu, Heng-Shan Wang, Dong Liang, Cai Yi Wang, Dong-Chan Oh, Donghwa Kim
Publikováno v:
Journal of Natural Products. 82:3056-3064
Three new germacrane sesquiterpenoid-type alkaloids with an unusual Δ8-7,12-lactam moiety, glechomanamides A-C (1-3), and two pairs of 7,12-hemiketal sesquiterpenoid epimers (4a/b, 5a/b) were isolated from Salvia scapiformis. Their structures were e
Autor:
Thi-Thu-Trang Luu, Ruoci Hu, Donghwa Kim, Sang Kook Lee, Cai Yi Wang, Ji Yun Lee, Hee-Juhn Park
Publikováno v:
Journal of Natural Products. 82:3140-3149
A flavonoid glycoside, quercitrin (1), and two phenylpropanoyl sucrose derivatives, vanicoside B (2) and lapathoside C (3), were isolated for the first time from the herb Persicaria dissitiflora. Vanicoside B (2) exhibited antiproliferative activity
Publikováno v:
J Phys Chem Lett
Bitter taste receptors (TAS2Rs) function in taste perception, but are also expressed in many extraoral tissues, presenting attractive therapeutic targets. TAS2R5s expressed on human airway smooth muscle cells can induce bronchodilation for treating a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7878cf8d1d31d688fbee42bd662e3aca
https://europepmc.org/articles/PMC8650975/
https://europepmc.org/articles/PMC8650975/
Autor:
Ashley Goss, Donghwa Kim, Maria A. Castaño, Eric M. Lewandowski, Jung A. Woo, Stephen B. Liggett, Yu Chen
Publikováno v:
FASEB J
Bitter taste receptor-14 (TAS2R14) is a GPCR also expressed on human airway smooth muscle cells, which signals to intracellular [Ca(2+)], resulting in relaxation of the airway, and is a novel target for bronchodilators. Here, we examine long-term, ag
Publikováno v:
The Journal of Biological Chemistry
For most G protein-coupled receptors, the third intracellular loop (IL3) and carboxy-terminal tail (CT) are sites for G protein-coupled receptor kinase (GRK)-mediated phosphorylation, leading to β-arrestin binding and agonist-specific desensitizatio