Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ann Leonard"'
Autor:
Paulina Aldana-Hernández, Kelly-Ann Leonard, Jonathan M. Curtis, Catherine J. Field, René L. Jacobs, Yuan-Yuan Zhao
Publikováno v:
The Journal of Nutrition. 150:249-255
Background Choline, an essential nutrient, is required for cell membranes, lipoprotein secretion, and methyl-group metabolism. Recently, it has been proposed that excess dietary choline consumption is metabolized to trimethylamine (TMA) by the gut mi
Autor:
Jean Buteau, Jelske N. van der Veen, Rick Havinga, Folkert Kuipers, Randal Nelson, Kelly-Ann Leonard, John P. Kennelly, René L. Jacobs
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1695-1708 (2018)
Journal of Lipid Research, 59(9), 1695-1708. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of Lipid Research, 59(9), 1695-1708. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
De novo phosphatidylcholine (PC) synthesis via CTP:phosphocholine cytidylyltransferase-alpha (CT alpha) is required for VLDL secretion. To determine the precise role of de novo PC synthesis in intestinal lipid metabolism, we deleted CT alpha exclusiv
Autor:
Nicole Borel, Cory Ann Leonard, Hanna Marti, Lisbeth Nufer, Robert V. Schoborg, Jasmin Kuratli
Introduction . Chlamydia trachomatis (Ct) is an obligate intracellular bacterium, causing a range of diseases in humans. Interactions between chlamydiae and antibiotics have been extensively studied in the past. Hypothesis/Gap statement: Chlamydial i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b289fb8a81a899e92c2a1363dbce4f8e
Autor:
Jessy Azarcoya-Barrera, Jonathan M. Curtis, Yuan-Yuan Zhao, Susan Goruk, Catherine J. Field, Randal Nelson, René L. Jacobs, Caroline Richard, Kelly-Ann Leonard, Jelske N. van der Veen, Paulina Aldana-Hernández
Publikováno v:
The Journal of Nutritional Biochemistry. 92:108617
Choline is an essential nutrient required for various biological processes. Eggs, dairy, and meat are rich in phosphatidylcholine (PC), whereas cereal and legumes are rich in free choline. Excess dietary choline leads to increase plasma trimethylamin
Autor:
Nicole Borel, Christian Blenn, Cory Ann Leonard, Hanna Marti, Theresa Pesch, Paul R. Torgerson, Jasmin Kuratli
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology, Vol 9 (2018)
Chlamydia trachomatis is the major cause of infectious blindness and represents the most common bacterial sexually transmitted infection worldwide. Considering the potential side effects of antibiotic therapy and increasing threat of antibiotic resis
Autor:
Yun Jin Chen, Kia M. Peters, Rennian Wang, Krisha Patel, Taylor Woolnough, John P. Kennelly, René L. Jacobs, Meg Schuurman, Kelly-Ann Leonard, Cynthia G. Sawyez, Rachel B. Wilson, Brian G. Sutherland, Richard Zhang, Nica M. Borradaile, Alexandra M. Hetherington
Publikováno v:
Paediatrics Publications
Inhibition of eukaryotic elongation factor 1A1 (EEF1A1) with the marine compound didemnin B decreases lipotoxic HepG2 cell death in vitro and improves early stage non-alcoholic fatty liver disease (NAFLD) in young genetically obese mice. However, the
Publikováno v:
International Journal of Microbiology, Vol 2016 (2016)
International Journal of Microbiology
International Journal of Microbiology
Chlamydia pecorumcauses asymptomatic infection and pathology in ruminants, pigs, and koalas. We characterized the antichlamydial effect of the beta lactam penicillin G onChlamydia pecorumstrain 1710S (porcine abortion isolate). Penicillin-exposed and
Autor:
Jonathan M. Curtis, Spencer D. Proctor, René L. Jacobs, Robin P. da Silva, Susan Goruk, Karen B. Kelly, Donna F. Vine, Erin D. Lewis, Kelly-Ann Leonard, Catherine J. Field
Publikováno v:
The Journal of Nutritional Biochemistry. 26:1077-1083
Choline is a precursor to phosphatidylcholine (PC), a structural molecule in cellular membranes that is crucial for cell growth and function. PC is also required for the secretion of lipoprotein particles from liver and intestine. Choline requirement
Autor:
Jonathan M. Curtis, René L. Jacobs, Benjamin P. Willing, Yumna Zia, Tingting Ju, Jelske N. van der Veen, Catherine J. Field, Ala Al Rajabi, Randal Nelson, Kelly-Ann Leonard, Si Mi, Aducio Thiesen
Publikováno v:
The Journal of nutrition. 148(10)
Background Phosphatidylethanolamine N-methyltransferase (PEMT) converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/-/low density lipoprotein receptor (Ldlr)-/- mice have significantly reduced plasma lipids and are protected against athero
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1841:1639-1646
Non-alcoholic fatty liver disease encompasses a wide spectrum of liver damage including steatosis, non-alcoholic steatohepatitis, fibrosis and cirrhosis. We have previously reported that creatine supplementation prevents hepatic steatosis and lipid p