Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Margery A. Connelly"'
Autor:
David L. Williams, Margery A. Connelly
Publikováno v:
Current Opinion in Lipidology. 15:287-295
This review will survey recent findings on the cholesterol transport and scavenger functions of scavenger receptor BI. Although scavenger receptor BI and CD36 bind many of the same ligands, these two receptors have very specific lipid transport funct
Autor:
Libo Wang, Margery A. Connelly, Anne G. Ostermeyer, David L. Williams, Deborah A. Brown, Hsu-hsin Chen
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 4, Pp 807-815 (2003)
Free cholesterol (FC) has been reported to efflux from cells through caveolae, which are 50–100 nm plasma membrane pits. The 22 kDa protein caveolin-1 is concentrated in caveolae and is required for their formation. The HDL scavenger receptor BI (S
Autor:
Yves L. Marcel, Douglas M Lublin, Vivian Franklin, Margery A. Connelly, Philippe G. Frank, Michael P. Lisanti, David L. Williams
Publikováno v:
Biochemistry. 41:11931-11940
Caveolae are 50-100 nm plasma membrane invaginations, which function in cell signaling, in transcytosis, and in regulating cellular cholesterol homeostasis. These subcompartments of the plasma membrane are characterized by the presence of caveolin pr
Autor:
Margery A. Connelly, George H. Rothblat, Seth M. Klein, Drazul D, Stoudt G, de la Llera-Moya M, Pascale Monzo, Fournier N, David L. Williams, P. G. Yancey
Publikováno v:
Biochemistry. 40:5249-5259
Scavenger receptor BI (SR-BI) mediates the selective uptake of high-density lipoprotein (HDL) cholesteryl ester (CE), a process by which HDL CE is taken into the cell without degradation of the HDL particle. In addition, SR-BI stimulates the bi-direc
Publikováno v:
Endocrine Research. 26:639-651
Adrenal cells obtain cholesterol for steroid production via the selective uptake of cholesteryl ester (CE) from HDL particles, a process in which CE is transferred to the plasma membrane without degradation of the HDL particle. Although this process
Autor:
Margery A. Connelly, David L. Williams, Stoudt G, George H. Rothblat, Christian Ae, de la Llera-Moya M, Haynes Mp, Ginny Kellner-Weibel
Publikováno v:
Biochemistry. 39:221-229
Previous studies have shown that scavenger receptor BI (SR-BI) stimulates the bidirectional flux of free cholesterol (FC) between HDL and SR-BI-expressing cells. A major component of the enhanced FC flux appears to occur independently of HDL binding
Publikováno v:
Journal of Biological Chemistry. 274:29733-29739
Scavenger receptor, class B, type I (SR-BI) is a cell-surface glycoprotein that mediates selective uptake of high density lipoprotein cholesteryl ester (CE) without the concomitant uptake and degradation of the particle. We have investigated the endo
Publikováno v:
Journal of Biological Chemistry. 274:41-47
Scavenger receptor BI (SR-BI) mediates the selective uptake of high density lipoprotein (HDL) cholesteryl ester (CE), a process by which HDL CE is taken into the cell without internalization and degradation of the HDL particle. The biochemical mechan
Autor:
David L. Williams, Margery A. Connelly, Michael C. Phillips, Wendy Akmentin, Yinan Peng, Sissel Lund-Katz
Receptor-mediated trafficking of cholesterol between lipoproteins and cells is a fundamental biological process at the organismal and cellular levels. In contrast to the well-studied pathway of LDL receptor-mediated endocytosis, little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c5ee56bb5ab34e097c4120383897c9
https://europepmc.org/articles/PMC307555/
https://europepmc.org/articles/PMC307555/
Autor:
Margarita de la Llera-Moya, George H. Rothblat, Yinan Peng, David L. Williams, Margery A. Connelly, Denise Drazul-Schrader
Publikováno v:
The Journal of biological chemistry. 278(28)
Scavenger receptor class B, type I (SR-BI) shows a variety of effects on cellular cholesterol metabolism, including increased selective uptake of high density lipoprotein (HDL) cholesteryl ester, stimulation of free cholesterol (FC) efflux from cells