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Publikováno v:
Folia Morphologica. 81:931-941
Background: Adipose tissue-derived mesenchymal stem cells (AD-MSCs) were proved to differentiate into insulin-producing cells (IPCs), but the amount of insulin secreted was relatively low compared to the insulin secreted by mature pancreatic islets.
Publikováno v:
Nutr Neurosci
Diets high in saturated fat (HFD) disrupt dopamine neurotransmission, whereas fasting alters tonic and phasic dopamine release to drive motivation and food consumption. However, functional compartments in the nucleus accumbens (NAc) influencing these
Autor:
Gulce Naz Yazici, Halis Suleyman, Ercument Keskin, Mehmet Gül, Abdullah Erdogan, Mukadder Sunar
Publikováno v:
Revista Internacional de Andrología. 20:S17-S23
This study aimed to biochemically and histopathologically investigate the effect of sunitinib on oxidative testicular damage induced by ischemia/reperfusion in rats.Experimental animals were divided into three groups of six rats each: testicular tors
Autor:
Fatima Rasool, Muhammad Irfan Siddique, Muhammad Farhan Sohail, Muhammad Sarfraz, Muhammad Nabeel Shahid, Muhammad Ovais Omer, Saima Tufail, Haliza Katas
Publikováno v:
Current Drug Delivery. 19:534-546
Introduction: The pleiotropic effects of statins are recently explored for wound healing through angiogenesis and lymph-angiogenesis that could be of great importance in diabetic wounds. Aim: The aim of the present study is to fabricate nanofilm embe
Publikováno v:
Neuroscience. 497:118-133
Systemic administration of drugs that activate the noradrenergic or glucocorticoid system potentiates aversive memory consolidation and reconsolidation. The opposite happens with the stimulation of endocannabinoid signaling under certain conditions.
Autor:
Mohamed Abouelkheir
Publikováno v:
Current Molecular Pharmacology. 15:582-588
Background: We previously tested two angiotensin-converting enzyme (ACE) inhibitors and two dipeptidyl peptidase-4 (DPP-4) inhibitors for dual enzyme inhibitory effect. Only two DPP-4 inhibitors, linagliptin and sitagliptin, were able to inhibit ACE.
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:412-421
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors including central obesity, hypertension, insulin resistance, dyslipidemia, and hyperglyemia. MetS is found to be a positive predictor of cardiovascular morbidity and mortality. The
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:1601-1610
Background: Bowl or colorectal cancer (CRC) is the third most common type of cancer with about two million new cases every year. CRC is the second leading cause of cancer related mortalities. Objective: The study aims to evaluate the anticancer activ
Publikováno v:
Biomedical Journal. 45:387-395
Background Nitrite stimulates insulin secretion from pancreatic β-cells; however, the underlying mechanisms have not been completely addressed. The aim of this study is to determine effect of nitrite on gene expression of SNARE proteins involved in
Publikováno v:
Cannabis Cannabinoid Res
INTRODUCTION: Cannabidiol (CBD) is a major cannabinoid extracted from Cannabis sativa with no abuse potential. Data from recent rodent studies suggest that amelioration of alcohol-motivated behaviors may be one of the numerous pharmacological effects