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Autor:
Mahban Rahimifard, Maryam Baeeri, Behnaz Bameri, Rohollah Hosseini, Mahedeh Samadi, Mohammad Abdollahi, Majid Masoudi Fard, Madiha Khalid, Hamed Haghi-Aminjan, Mohammad Reza Hooshangi Shayesteh, Shokoufeh Hassani, Maryam Armandeh
Publikováno v:
Toxicology Mechanisms and Methods. 31:631-643
Aluminum phosphide (AlP) causes serious poisoning in which severe cardiac suppression is the significant lethal consequence. According to evidence, levosimendan can exert outstanding cardiac support and protection in different pathological conditions
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Constipation is one of the chronic gastrointestinal functional diseases. It seriously affects the quality of life. Cistanche deserticola (C. deserticola) can treat constipation obviously, but its mechanism has not been clarified. We suppos
Autor:
Kambiz Hassanzadeh, Arman Rahimmi, Rita Maccarone, Esmael Izadpanah, Massimo Corbo, Mohammad Raman Moloudi, Marco Feligioni
Publikováno v:
Brain Research Bulletin. 173:184-192
Parkinson's disease (PD) and diabetes mellitus share similar pathophysiological characteristics, genetic and environmental factors. It has been reported that people with diabetes mellitus appear to have a remarkable higher incidence of PD than age ma
Autor:
Collins U. Ibeji, Veronica F. Salau, Ochuko L. Erukainure, Vishal Bharuth, Tosin A. Olasehinde, Md. Shahidul Islam
Publikováno v:
Neuroscience Research. 169:57-68
Reduced glucose uptake usually occurs in type 2 diabetes due to down-regulation of brain glucose transporters. The potential of kolaviron, a biflavonoid from Garcinia kola to stimulate glucose uptake and suppress glucose-induced oxidative toxicity we
Autor:
Tong Li, Ruolan Gu, Xiaoxia Zhu, Guifang Dou, Taoyun Liu, Zhiyun Meng, Su Han, Peng Han, Jiarui Gao, Zhuona Wu, Hui Gan
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 11, Iss 9, Pp 2468-2489 (2021)
FEBS Open Bio, Vol 11, Iss 9, Pp 2468-2489 (2021)
Unfractionated heparin (UFH) is an anionic glycosaminoglycan that is widely used to prevent blood clotting. However, in certain cases, unwanted side effects can require it to be neutralized. Protamine sulfate (PS), a basic peptide rich in arginine, i
Autor:
Fatemeh Sheikhbahaei, Mohammad Khazaei, Seyed Noureddin Nematollahi-Mahani, Saeed Khazayel, Mozafar Khazaei
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Objective: Angiogenesis plays a dominant role in many pathophysiologic disorders, including cancer. Tranilast, which is an anti-fibrotic drug, is also suggested as an anti-angiogenesis agent. As Teucrium polium (TP) is known as an herbal medicine wit
Publikováno v:
Psychopharmacology. 238:3183-3191
Kratom (Mitragyna speciosa Korth), a native medicinal plant of Southeast Asia, is proposed to exhibit potential therapeutic value as an opioid substitute. However, studies of its negative emotional states resulting from withdrawal particularly of its
Publikováno v:
Current Molecular Pharmacology. 14:635-645
Background and Aim: Cisplatin (cis-diamminedichloroplatinum [II]; CDDP) is the most widely used drug in cancer chemotherapy. The nephrotoxicity of CDDP is one of its major side effects. Vorinostat (VST) has been reported to have antioxidant and anti-
Fabrication of Rapidly Separable Microneedles for Transdermal Delivery of Metformin on Diabetic Rats
Publikováno v:
Journal of Pharmaceutical Sciences. 110:3004-3010
In this work, the rapidly separable microneedles (MNs) consisted of needle-tips and supporting bases have been fabricated by a step-by-step coating method. Poly (vinyl alcohol) (PVA) have been used to prepare the needle-tips of MNs in which they are
Autor:
David E. Blask, Robert P Tirrell, Leonard A. Sauer, Erin M. Dauchy, Leslie K. Davidson, Steven M. Hill, Robert T. Dauchy
Publikováno v:
Comp Med
Melatonin, the circadian nighttime neurohormone, and eicosapentaenoic acid (EPA) and docosahexaenoic acids (DHA), which are omega-3 fatty acids (FA) found in high concentrations in fish oil (FO) and plants, abrogate the oncogenic effects of linoleic