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Autor:
Xiaohong Dai, Peng Liu, Xueping Yu, Ming-Yue Li, Wei Teng, Xin Wen, Xin-Yang Yu, Wei Zou, Qi An
Publikováno v:
Journal of Molecular Neuroscience
Intracerebral haemorrhage (ICH) can be a catastrophic event; even if the initial stages of the pathology were well-managed, a number of patients experience varied residual neurological deficits following the insult. Ferroptosis is a recently identifi
Autor:
Sandra Gabriela Vlachovsky, Claudia Silberstein, Nora Paula Goette, Elvira Arrizurieta, Fernando R. Ibarra, Luis A. Di Ciano, Pablo Javier Azurmendi, Elisabet M. Oddo
Publikováno v:
Experimental Physiology. 106:2107-2123
New findings What is the central question of this study? In a model of salt-sensitive hypertension in ovariectomized (oVx) adult Wistar rats, we evaluated the expression of proteins related to sodium transport in peripheral blood mononuclear cells (P
Autor:
R. Ravindran, Rajendran Harishkumar, Chinnadurai Immanuel Selvaraj, Johnsamuel Godwin Christopher
Publikováno v:
Cardiovascular Toxicology. 21:947-963
Chemotherapeutic drugs are a known factor that impairs the system of life due to their severe side effects. A more worrying fact is that the patients administered with doxorubicin fall under the risk of cardiotoxicity. The evolution of exploring plan
Autor:
Yuichiro J. Suzuki, Valerii E. Orel, Sergiy G. Gychka, Mykhailo Krotevych, Lyudmyla Garmanchuk, L. A. Syvak, Helena Tsvir, Iryna V. Sheina, O. Rykhalskyi, Vladyslava Rybka, Nataliia V. Shults, Olga Dasyukevich, Valerii В Orel, Dmytro Tsvir
Publikováno v:
Electromagnetic Biology and Medicine. 40:475-487
We compare the effects of an extremely low-frequency electromagnetic field (EMF) with the chemotherapeutic agent doxorubicin (DOX) on tumor growth and the hepatic redox state in Walker-256 carcinosarcoma-bearing rats. Animals were divided into five g
Publikováno v:
Pharmacological Reports
Background Preclinical and clinical studies have indicated that impaired endogenous synthesis of glutathione during early postnatal development plays a significant role in the pathophysiology of schizophrenia. Moreover, some studies have suggested th
Publikováno v:
Andrology. 10:143-153
BACKGROUND Intracavernous pressure measurement following cavernous nerve electrostimulation has been extensively adopted for the evaluation of erectile function in animals. However, the effect of measurement time and acidosis during anesthesia is sti
Vitamin D modulates hepatic microRNAs and mitigates tamoxifen‐induced steatohepatitis in female rats
Autor:
Enas A Abd El-Haleim, Nada A Sallam
Publikováno v:
Fundamental & Clinical Pharmacology. 36:338-349
Background Tamoxifen (TAM) is a life-saving and cost-effective drug widely used in the prevention and treatment of breast cancer. However, the adverse effects of tamoxifen can lead to non-adherence and poor patient outcomes. Therefore, exploring nove
Autor:
Junichiro James Kazama, Masafumi Fukagawa, Ryosuke Ozasa, Takayoshi Nakano, Shingo Fukuma, Suguru Yamamoto, Akemi Ito, Shin Goto, Shunichi Fukuhara, Yoshihiro Onishi, Takuya Wakamatsu, Koji Matsuo, Hideyuki Yamato, Chisato Miyakoshi, Tadao Akizawa, Ichiei Narita, Yoshiko Iwasaki, Kennichi Tanaka
Publikováno v:
Journal of Bone and Mineral Research. 36(1):67-79
Wakamatsu T., Iwasaki Y., Yamamoto S., et al. Type I Angiotensin II Receptor Blockade Reduces Uremia-Induced Deterioration of Bone Material Properties. Journal of Bone and Mineral Research, 36, 1, 67. https://doi.org/10.1002/jbmr.4159.
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Publikováno v:
Anti-Cancer Drugs. 33:e525-e533
Cancer is related to the cellular proliferative state. Increase in cell-cycle regulatory function augments cellular folate pool. This pathway is therapeutically targeted. A number of drugs influences this metabolism, that is, folic acid, folinic acid
Autor:
Xiao-Yu Liu, Guangwen Li, Li-Fei Zheng, Xiao-Li Zhang, Yue Zhang, Jing-Ting Yan, Jin-Xia Zhu, Xiao-Yan Feng, Jing-Hua Liu
Publikováno v:
Cell and Tissue Research. 386:249-260
Patients with Parkinson's disease (PD) have a higher incidence rate of duodenal ulcers. The mucus barrier provides the first line of defense for duodenal mucosal protection. However, it is unknown whether duodenal mucus secretion is affected in PD. I