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Publikováno v:
Canadian Journal of Physiology and Pharmacology. 100:412-421
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors including central obesity, hypertension, insulin resistance, dyslipidemia, and hyperglyemia. MetS is found to be a positive predictor of cardiovascular morbidity and mortality. The
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0193853 (2018)
PLoS ONE, Vol 13, Iss 3, p e0193853 (2018)
17β-estradiol treatment has shown benefit against schizophrenia symptoms, however longterm use may be associated with negative side-effects. Selective estrogen receptor modulators, such as raloxifene and tamoxifen, have been proposed as suitable alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011797b2121308140f7e5e9e0a964b89
Autor:
Nadeem Sayyed, Imran Kazmi, Syed Sarim Imam, Waleed H. Almalki, Muhammad Nadeem, Mohammed M. Ghoneim, Fahad A. Al-Abbasi, Sultan Alshehri, Muhammad Afzal
Publikováno v:
ACS Chemical Neuroscience. 12:4587-4597
The phytogenic flavanol component of the plant Rhusverniciflua Stokes is fustin which is implicated in various disease aliments and has promising therapeutic efficacy and a long history of its uses in the Indian medicinal system. The present study in
Publikováno v:
Journal of Cellular Physiology. 237:1299-1314
The lung is the first and most frequent organ to fail among sepsis patients. The mortality rate of sepsis-related acute lung injury (ALI) is high. Despite appropriate antimicrobial therapy, no treatment strategies are available for sepsis-induced ALI
Autor:
Serdar Ferit Toprak, Muhammed Ayral
Publikováno v:
Somatosensory & Motor Research. 38:347-352
Introduction Cisplatin (CDDP) is a widely used antineoplastic drug. However, its use is limited due to the ototoxic side effects. In this study, the effects of ethyl pyruvate (EP), known for its antioxidant and anti-inflammatory effects, against CDDP
Autor:
Beata M. Wolska, Pieter P. de Tombe, Montamas Suntravat, R. John Solaro, Tuchakorn Lertwanakarn, Elda E. Sánchez, Kittipong Tachampa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-00282-x⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-00282-x⟩
Scientific Reports
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-00282-x⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-00282-x⟩
Beta-cardiotoxin (β-CTX) from the king cobra venom (Ophiophagus hannah) was previously proposed as a novel β-adrenergic blocker. However, the involvement of β-adrenergic signaling by this compound has never been elucidated. The objectives of this
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 99:1088-1096
Metabolic side effects of atypical antipsychotics are an important cause of deterioration of cognitive function and failure of drug adherence. The antifatty effect trypsin/chymotrypsin (T/C) and their mechanisms of action remain unclear. To investiga
Publikováno v:
J Physiol
Pulmonary hypertension is characterized by sustained vasoconstriction and remodelling of the small pulmonary arteries, which is associated with persistent depolarization of the resting membrane potential (Em ) of pulmonary arterial smooth muscle cell
Autor:
Ali Sharif, Azhar Rasul, Sobia Younas, Mirza Muhammad Faran Ashraf Baig, Mohamed M. Abdel-Daim, Mohammad Saleem, Muhammad Furqan Akhtar, Ammara Saleem
Publikováno v:
Birth Defects Research. 113:1407-1421
OBJECTIVES Tramadol, an atypical opioid, is clinically efficacious in treating moderate to severe pain. The aim of current study was to find out the toxicological effects of tramadol exposure to pregnant rats and fetuses during the late phase of preg
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 99:952-963
Isoniazid and rifampicin are crucial for treating tuberculosis (TB); however, they can cause severe hepatotoxicity leading to liver failure. Therapeutic options are limited and ineffective. We hypothesized that prophylaxis with quercetin attenuates i