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Anti–Tumor Necrosis Factor α versus Tocilizumab in the Treatment of Refractory Uveitic Macular Edema
Autor:
Thomas Moulinet, Mathilde Leclercq, Pascal Sève, Philip Bielefeld, Bahram Bodaghi, Julie Gueudry, Sara Touhami, Lucie Biard, Fanny Domont, Damien Sène, Bénédicte Rouvière, A.C. Desbois, Anaïs Andrillon, Patrice Cacoub, Thomas Sené, Georgina Maalouf, Carolla El Chamieh, David Saadoun
Publikováno v:
Ophthalmology. 129:520-529
Objective To analyze the factors associated with response (control of ocular inflammation and corticosteroid sparing effect) to biologics (anti-TNF-α agents and tocilizumab) in patients with refractory uveitic macular edema. Design Multicenter retro
Autor:
Ammar Mohammed Saeed Abdullah Almomin, Ali Hussain Ali Alhamza, Nassar Taha Yaseen Alibrahim, Ibrahim Hani Hussein, Majid Alabbood, Haider Ayad Alidrisi
Publikováno v:
Clinical Diabetology. 11:61-66
Background. The safety and efficacy of combination tablets of metformin plus sulfonylurea or plus dipeptidyl peptidase-4 inhibitors have not been studied previously. This study aimed to compare the efficacy and safety of Gliconorm versus Sitavia plus
Autor:
Mani Baskaran, Lei Zhou, David L. Silver, Hengtong Li, Qiao Fan, Ching-Yu Cheng, Simon Nusinovici, Tien Yin Wong, Jonathan G Crowston, Yih Chung Tham, Tin Aung, Sahil Thakur, Charumathi Sabanayagam
Publikováno v:
Ophthalmology. 129:285-294
Purpose We hypothesized that the effect of blood lipid–related metabolites on primary open-angle glaucoma (POAG) would differ according to specific lipoprotein particles and lipid sub-fractions. We investigated the associations of blood levels of l
Autor:
Simona E. Carbone, Stephen J. Keely, Andreacarola Urso, Daniel P. Poole, Christoph Korbmacher, Alexandr V. Ilyaskin, Nigel W. Bunnett
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Bile acids (BAs) are known to be important regulators of intestinal motility and epithelial fluid and electrolyte transport. Over the past two decades, significant advances in identifying and characterizing the receptors, transporters, and ion channe
Publikováno v:
Medicina Clínica (English Edition). 158:99-104
The modified Glasgow prognostic score (mGPS) has been reported to have a prognostic value in various patient populations. However, the prognostic significance of mGPS has not been studied inacute pulmonary embolism (APE).This study aimed to investiga
Autor:
Francisco Bosques-Padilla, Ramon Bataller, Guadalupe Garcia-Tsao, Ashwin Dhanda, Michael R. Lucey, Juan Pablo Arab, Debbie L. Shawcross, Joaquín Cabezas, Robert S. Brown, Richard D. Parker, Bernd Schnabl, Ashish Sinha, P. Mathurin, Ian A. Rowe, Elizabeth C. Verna, José Altamirano, Meritxell Ventura-Cots, Andrew Holt, C Anne McCune, Marco Arrese, Victor Vargas, Alexandre Louvet, Juan G. Abraldes
Publikováno v:
Clinical Gastroenterology and Hepatology. 20:e289-e297
Alcoholic hepatitis (AH) is a severe condition with poor short-term prognosis. Specific treatment with corticosteroids slightly improves short-term survival but is associated with infection and is not used in many centers. A reliable method to identi
Autor:
Marian E. Major, Nicole Frumento, Alexander W. Tarr, Johnathan D. Guest, Steven K. H. Foung, Arvind H. Patel, Alexis Figueroa, Jordan Salas, Jonathan K. Ball, Vanessa M. Cowton, Kaitlyn E. Clark, Heidi E. Drummer, Thomas R. Fuerst, Richard A. Urbanowicz, Sarah Cole, Brian G. Pierce, Zhen-Yong Keck, Mansun Law, Justin R. Bailey
Publikováno v:
Gastroenterology. 162:562-574
Background and Aims Development of a prophylactic hepatitis C virus (HCV) vaccine will require accurate and reproducible measurement of neutralizing breadth of vaccine-induced antibodies. Currently available HCV panels may not adequately represent th
Publikováno v:
GASTROENTEROLOGY. :67-72
The objective of this study was to evaluate the quality of life in patients with ulcerative colitis (UC) of moderate severity and concomitant subclinical atherosclerosis before and after combination treatment with statin and omega-3 polyunsaturated f
Publikováno v:
Journal of Hepatology. 76:86-92
Background & Aims Infliximab has been associated with drug-induced liver injury (DILI), particularly drug-induced autoimmune hepatitis (DIAIH). DIAIH is commonly treated with corticosteroids, but there is limited data on the efficacy of corticosteroi
Autor:
Yan Xie, Anirudh Prabu, Jacqueline Chen, Harold J. Boutte, Brad W. Warner, Todd Wylie, Kristine M. Wylie, Marc S. Levin, Nicholas O. Davidson, Deborah C. Rubin, Mackenzie Geisman, Vered Gazit, Phillip I. Tarr
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Loss of functional small bowel surface area causes short bowel syndrome (SBS), intestinal failure, and parenteral nutrition (PN) dependence. The gut adaptive response following resection may be difficult to predict, and it may take up to 2 yr to dete