Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Thomas C. Foster"'
Autor:
Stewart R. Hart, Thomas C. Foster, Robert C. Holley, Rebecca L. Scotland, John A. Blanchard, Barton R. Harris, Norman W. Pedigo, John M. Littleton, D. Alex Gibson, Mark A. Prendergast
Publikováno v:
Alcoholism: Clinical & Experimental Research. 27:1724-1735
Background: We recently reported that the sodium salt of acamprosate (Na-acamprosate) demonstrates the characteristics of an antagonist at metabotropic glutamate type 5 receptors (mGluR5s) rather than at N-methyl-d-aspartate receptors (NMDARs). Becau
Publikováno v:
Neurobiology of Aging. 24:839-852
The current study examined effects of chronic estradiol replacement on cognition and biomarkers of aging. Young, middle-aged, and aged rats were ovariectomized and implanted with blank capsules, or capsules containing high or low doses of estradiol b
Publikováno v:
Neuroscience. 113:89-97
Estradiol influences Ca(2+) regulation and Ca(2+)-dependent synaptic plasticity, suggesting estrogenic effects on Ca(2+)-dependent enzymes that regulate synaptic plasticity may mediate hormonal influences on cognition. In ovariectomized female rats,
Autor:
Thomas C. Foster, Ashok Kumar
Publikováno v:
Journal of Neurophysiology. 88:621-626
Disruption of Ca2+ homeostasis is hypothesized to mediate several electrophysiological markers of brain aging. Recent evidence indicates that estradiol can rapidly alter Ca2+-dependent processes in neurons through nongenomic mechanisms. In the curren
Publikováno v:
Hormones and Behavior. 34:163-170
This study investigated the role of the estrogen receptor alpha (ERalpha) in mediating performance on a spatial discrimination task, the Morris water maze. Spatial discrimination on this water escape task was examined in eight groups of gonadectomize
Publikováno v:
Brain research. 871(1)
This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or envir