Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marie-Christophe Boissier"'
Autor:
Natacha Bessis, Luca Semerano, Marianne Ziol, Jérôme Biton, Jörg Tost, Magali Breckler, Roxane Hervé, Marie-Christophe Boissier, Maxime Batignes, Florence Busato, Patrice Decker, Delphine Lemeiter, Gaëlle Clavel, Majda Lyna Mebrek, François Santinon
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.)References. 72(4)
OBJECTIVE To study the involvement of Treg cells expressing tumor necrosis factor receptor type II (TNFRII) in exerting control of inflammation in experimental models and in the response to anti-TNF treatments in patients with rheumatoid arthritis (R
Autor:
Maxime Batignes, Patrice Decker, François Santinon, Natacha Bessis, Marie-Christophe Boissier, Charlotte Pouchy, Luca Semerano, Benoît L. Salomon
Publikováno v:
Immune regulation.
Background In rheumatoid arthritis (RA), regulatory T cells (Tregs) are defective in their suppressive capacities and fail to control chronic inflammation. TNF-α is involved in inhibition of Treg differentiation and activation, likely via activation
Autor:
Jérôme Biton, Julie Quentin, Marie-Christophe Boissier, Pascale Louis-Plence, Patrice Decker, Allan Thiolat, Yves-Marie Pers, Natacha Bessis, Delphine Lemeiter, Christian Jorgensen, P. Portales, Luca Semerano
Publikováno v:
Arthritis & Rheumatology. 66:273-283
Objective The rationale for blocking interleukin-6 (IL-6) in rheumatoid arthritis (RA) lies chiefly in the proinflammatory effect of this cytokine. Few studies have evaluated the consequences of anti–IL-6 receptor (IL-6R) antibody treatment on Treg
Autor:
Patrice Decker, Ivan Jelcic, Britta Janina Wagner, Marie-Christophe Boissier, Dennis Lindau, Hans-Georg Rammensee, Maude Quettier, Matthieu Ribon, Julie Mussard, Viktoria M. Rönnefarth
Publikováno v:
European Journal of Immunology. 43:2101-2113
Polymorphonuclear leukocytes (PMNs) represent one of the first lines of defense against pathogens. TLR9 is normally expressed in endosomes/lysosomes where it is activated by pathogen-derived DNA. Here we show that freshly isolated human and mouse pri
Autor:
Marion Laborie, Natacha Bessis, Laure Delavallée, Delphine Lemeiter, Géraldine Grouard-Vogel, Marie-Christophe Boissier, Luca Semerano, Jérôme Biton
Publikováno v:
The Journal of Immunology. 186:3899-3910
CD4+CD25+Foxp3+ regulatory T cells (Treg) are involved in several autoimmune diseases, including rheumatoid arthritis. TNF-α blockers induce therapeutic benefits in rheumatoid arthritis via a variety of mechanisms. We aimed to characterize the impac
Autor:
Anne Denys, Marie-Christophe Boissier, Géraldine Falgarone, Jérôme Biton, Eric Assier, Natacha Bessis
Publikováno v:
Joint Bone Spine. 76:10-14
Modulation of the T-cell response depends chiefly on regulatory T cells (Treg), which express CD4 and CD25. Some Treg cells are present naturally, whereas others are induced in response to antigens. The immunomodulating effects of Treg cells are medi
Publikováno v:
Joint bone spine. 79(2)
TNFα is a cytokine that is central to the pathogenesis of several autoimmune diseases. More specifically, the deleterious effects of TNFα in rheumatoid arthritis (RA) are well established. The proinflammatory influence of TNFα in RA is related bot
Autor:
Marie-Christophe Boissier, Patrice Decker, Matthieu Ribon, Natacha Bessis, Allan Thiolat, Harpreet Singh-Jasuja, Hans-Georg Rammensee
Publikováno v:
Immunobiology. 218(1)
Dendritic cells (DC) play a key role in regulating immune responses and are the best professional antigen-presenting cells. Two major DC populations are defined in part according to cell surface CD11c expression levels. Unexpectedly, we observed that
Autor:
Abokouo Zago, Sandrine Rullé, Marie-Christophe Boissier, Géraldine Falgarone, Olivier Jaen, Natacha Bessis
Dendritic cells (DCs) mediate interactions between innate and specific immunity and may induce regulatory mechanisms. We investigated the effects of modulated DCs in mice with collagen-induced arthritis (CIA) and tested the responses of cells to indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14193dfbfde2415fb203daa7ae7ae891
https://europepmc.org/articles/PMC2632710/
https://europepmc.org/articles/PMC2632710/
Publikováno v:
Joint bone spine. 72(1)
Innate immunity is the first line of defense against pathogenic microorganisms (bacteria, viruses, fungi, and parasites). After a long period of neglect, innate immunity is again recognized as a key mechanism not only in preventing invasion of the bo