Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Ekaterina S Jordanova"'
Autor:
Dieuwke L. Marvin, Vivian M. Spaans, Cor D. de Kroon, Roderick C. Slieker, Maryam Khelil, Peter ten Dijke, Laila Ritsma, Ekaterina S. Jordanova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cervical cancer is the fourth most common cancer in women worldwide. Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are the most common histological types, with AC patients having worse prognosis. Over the last two decades, incidence rates of
Externí odkaz:
https://doaj.org/article/190b94ac4d134e1ab0dd7b4f0e1a1bef
Autor:
A. Marijne Heeren, Ekaterina S. Jordanova, Constantijne H. Mom, Maaike C G Bleeker, Henry Zijlmans, Tanja D. de Gruijl, Sinéad M. Lougheed, Anita G.M. Stam, Noëlle Pocorni, Awa A Gassama, G.G. Kenter, Jossie Rotman
Publikováno v:
Clinical Cancer Research, 26(14), 3791-3802. American Association for Cancer Research Inc.
Rotman, J, Heeren, A M, Gassama, A A, Lougheed, S M, Pocorni, N, Stam, A G M, Bleeker, M C G, Zijlmans, H J M A A, Mom, C H, Kenter, G G, Jordanova, E S & de Gruijl, T D 2020, ' Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8 + T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma ', Clinical Cancer Research, vol. 26, no. 14, pp. 3791-3802 . https://doi.org/10.1158/1078-0432.CCR-19-3826
Clinical cancer research, 26(14), 3791-3802. American Association for Cancer Research Inc.
Rotman, J, Heeren, A M, Gassama, A A, Lougheed, S M, Pocorni, N, Stam, A G M, Bleeker, M C G, Zijlmans, H J M A A, Mom, C H, Kenter, G G, Jordanova, E S & de Gruijl, T D 2020, ' Adenocarcinoma of the Uterine Cervix Shows Impaired Recruitment of cDC1 and CD8 + T Cells and Elevated β-Catenin Activation Compared with Squamous Cell Carcinoma ', Clinical Cancer Research, vol. 26, no. 14, pp. 3791-3802 . https://doi.org/10.1158/1078-0432.CCR-19-3826
Clinical cancer research, 26(14), 3791-3802. American Association for Cancer Research Inc.
Purpose:Adenocarcinoma of the uterine cervix is the second most common type of cervical cancer after squamous cell carcinoma (SCC). Although both subtypes are treated similarly, patients with adenocarcinoma have a worse prognosis. In this study, immu
Autor:
Noelle Pocorni, A. Marijne Heeren, Ekaterina S. Jordanova, Iske F. van Luijk, Jeroen Kole, Joost Lakeman, Renee X. de Menezes, Cornelis D. de Kroon, Tjalling Bosse, Gemma G. Kenter
Publikováno v:
Cancer Immunology, Immunotherapy, 68(11), 1759-1767
Cancer immunology, immunotherapy, 68(11), 1759-1767. Springer Science and Business Media Deutschland GmbH
Heeren, A M, van Luijk, I F, Lakeman, J, Pocorni, N, Kole, J, de Menezes, R X, Kenter, G G, Bosse, T, de Kroon, C D & Jordanova, E S 2019, ' Neoadjuvant cisplatin and paclitaxel modulate tumor-infiltrating T cells in patients with cervical cancer ', Cancer Immunology, Immunotherapy, vol. 68, no. 11, pp. 1759-1767 . https://doi.org/10.1007/s00262-019-02412-x, https://doi.org/10.1007/s00262-019-02412-x
Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy, 68(11), 1759-1767. Springer Science and Business Media Deutschland GmbH
Cancer immunology, immunotherapy, 68(11), 1759-1767. Springer Science and Business Media Deutschland GmbH
Heeren, A M, van Luijk, I F, Lakeman, J, Pocorni, N, Kole, J, de Menezes, R X, Kenter, G G, Bosse, T, de Kroon, C D & Jordanova, E S 2019, ' Neoadjuvant cisplatin and paclitaxel modulate tumor-infiltrating T cells in patients with cervical cancer ', Cancer Immunology, Immunotherapy, vol. 68, no. 11, pp. 1759-1767 . https://doi.org/10.1007/s00262-019-02412-x, https://doi.org/10.1007/s00262-019-02412-x
Cancer Immunology, Immunotherapy
Cancer Immunology, Immunotherapy, 68(11), 1759-1767. Springer Science and Business Media Deutschland GmbH
Resistance to chemotherapy is widely recognized as one of the major factors limiting therapeutic efficacy and influences clinical outcomes in patients with cancer. Many studies on various tumor types have focused on combining standard-of-care chemoth
Publikováno v:
Cancer Immunology, Immunotherapy
Rotman, J, Koster, B D, Jordanova, E S, Heeren, A M & de Gruijl, T D 2019, ' Unlocking the therapeutic potential of primary tumor-draining lymph nodes ', Cancer Immunology, Immunotherapy, vol. 68, no. 10, pp. 1681-1688 . https://doi.org/10.1007/s00262-019-02330-y
Rotman, J, Koster, B D, Jordanova, E S, Heeren, A M & de Gruijl, T D 2019, ' Unlocking the therapeutic potential of primary tumor-draining lymph nodes ', Cancer Immunology, Immunotherapy, vol. 68, no. 10, pp. 1681-1688 . https://doi.org/10.1007/s00262-019-02330-y
Lymph nodes draining the primary tumor are essential for the initiation of an effective anti-tumor T-cell immune response. However, cancer-derived immune suppressive factors render the tumor-draining lymph nodes (TDLN) immune compromised, enabling tu
Autor:
Linda Larbi Chérif, Virginie Fourchotte, Suzy Scholl, Maud Kamal, Ivan Bièche, Ekaterina S. Jordanova, Guillaume Bataillon, Anne de la Rochefordiere, Carine Tran-Perennou, Emmanuelle Jeannot, Aurélien Latouche, Corine M. Beaufort, Heiko von der Leyen, Els M.J.J. Berns, Christophe Le Tourneau, Claire Bonneau, Fabrice Lecuru, Marie-Ange Calméjane, Charlotte Lecerf, Laurence Raizonville, Marina Popovic, Kirsten Ruigrok-Ritstier, Roman Rouzier, Celia Dupain, Sylvain Dureau, Diana Bello Roufai, Marie-Emmanuelle Legrier
Publikováno v:
Clinical Cancer Research, 27(21), 5869-5877. American Association for Cancer Research Inc.
Jeannot, E, Latouche, A, Bonneau, C, Calmejane, M-A, Beaufort, C, Ruigrok-Ritstier, K, Bataillon, G, Cherif, L L, Dupain, C, Lecerf, C, Popovic, M, de la Rochefordiere, A, Lecuru, F, Fourchotte, V, Jordanova, E S, von der Leyen, H, Tran-Perennou, C, Legrier, M-E, Dureau, S, Raizonville, L, Roufai, D B, le Tourneau, C, Bieche, I, Rouzier, R, Berns, E M J J, Kamal, M & Scholl, S 2021, ' Circulating HPV DNA as a marker for early detection of relapse in patients with cervical cancer ', Clinical Cancer Research, vol. 27, no. 21, pp. 5869-5877 . https://doi.org/10.1158/1078-0432.CCR-21-0625
Jeannot, E, Latouche, A, Bonneau, C, Calmejane, M-A, Beaufort, C, Ruigrok-Ritstier, K, Bataillon, G, Cherif, L L, Dupain, C, Lecerf, C, Popovic, M, de la Rochefordiere, A, Lecuru, F, Fourchotte, V, Jordanova, E S, von der Leyen, H, Tran-Perennou, C, Legrier, M-E, Dureau, S, Raizonville, L, Roufai, D B, le Tourneau, C, Bieche, I, Rouzier, R, Berns, E M J J, Kamal, M & Scholl, S 2021, ' Circulating HPV DNA as a marker for early detection of relapse in patients with cervical cancer ', Clinical Cancer Research, vol. 27, no. 21, pp. 5869-5877 . https://doi.org/10.1158/1078-0432.CCR-21-0625
Purpose: Almost all cervical cancers are caused by human papillomavirus (HPV) and patients with advanced stage are at high risk for relapse. Circulating HPV DNA (HPV ctDNA) may serve as a residual tumor marker at the end of chemoradiation or to predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d2987fb5954069d5b9f48003b7f0a2
https://pure.eur.nl/en/publications/ac41fba9-112e-4932-949d-5319bd3d15ec
https://pure.eur.nl/en/publications/ac41fba9-112e-4932-949d-5319bd3d15ec
Autor:
Renske D.M. Steenbergen, Renée X. de Menezes, Wim Vos, Maaike C G Bleeker, Taylor Saunders-Wood, Jossie Rotman, Heather Griffin, John Doorbar, Gemma G. Kenter, Sanne Samuels, Maryam Khelil, Ke Zheng, Brendy E.W.M. van den Akker, Ekaterina S. Jordanova
Publikováno v:
Cancer Research, 81(7), 1909-1921. American Association for Cancer Research Inc.
Khelil, M, Griffin, H, Bleeker, M C G, Steenbergen, R D M, Zheng, K, Saunders-Wood, T, Samuels, S, Rotman, J, Vos, W, van den Akker, B E, de Menezes, R X, Kenter, G G, Doorbar, J & Jordanova, E S 2021, ' Delta-like ligand-notch1 signaling is selectively modulated by HPV16 e6 to promote squamous cell proliferation and correlates with cervical cancer prognosis ', Cancer Research, vol. 81, no. 7, pp. 1909-1921 . https://doi.org/10.1158/0008-5472.CAN-20-1996
Khelil, M, Griffin, H, Bleeker, M C G, Steenbergen, R D M, Zheng, K, Saunders-Wood, T, Samuels, S, Rotman, J, Vos, W, van den Akker, B E, de Menezes, R X, Kenter, G G, Doorbar, J & Jordanova, E S 2021, ' Delta-like ligand-notch1 signaling is selectively modulated by HPV16 e6 to promote squamous cell proliferation and correlates with cervical cancer prognosis ', Cancer Research, vol. 81, no. 7, pp. 1909-1921 . https://doi.org/10.1158/0008-5472.CAN-20-1996
Human papillomavirus (HPV) drives high-grade intraepithelial neoplasia and cancer; for unknown reasons, this occurs most often in the cervical transformation zone. Either mutation or HPV E6–driven inhibition of Notch1 can drive neoplastic developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ed5b452bf07faa2097cb26fd0475d5
https://research.vumc.nl/en/publications/6217b3f2-ec90-4073-9dbe-b428ae4d07dd
https://research.vumc.nl/en/publications/6217b3f2-ec90-4073-9dbe-b428ae4d07dd
Autor:
Pauline Wimberger, Anne Floquet, Michel Fabbro, Marina Popovic, Suzy Scholl, Goran Malenkovic, Noreen Gleeson, Jean-Marc Classe, Elodie Girard, Eleonor Rivin del Campo, Delphine Garbay, Mathieu Minsat, Sylvain Dureau, Katarina Koprivsek, Peter Hillemanns, Eric Deutsch, Nicolas Servant, Maud Kamal, Coraline Dubot, Ekaterina S. Jordanova, Heiko von der Leyen, Charlotte Ngo, Leanne de Koning, Branislav Djuran, Sorin Dema, Marius Craina, Anne de la Rochefordiere, Aljosa Mandic, Charles Coutant, Jean Guillaume Feron, Madalin Margan, Nina Samet, Els M.J.J. Berns, Sanne Samuels, István Nagy, Philippe Morice, Pierre Emmanuel Colombo, Roman Rouzier, Balázs Bálint, Henry Zijlmans, Philippe Hupé, Frédéric Marchal, Gemma G. Kenter, Alis Dema, Nathalie Mesgouez-Nebout, Pierre Gestraud, Fabrice Lecuru, Virginie Fourchotte, Attila Kereszt, Frédéric Guyon, Nicolas de Saint-Jorre, Alexia Savignoni, Pierre Fumoleau, Christine Kerr
Publikováno v:
EBioMedicine
EBioMedicine, Vol 57, Iss, Pp 102875-(2020)
EBioMedicine, Vol 57, Iss, Pp 102875-(2020)
BACKGROUND: There is a lack of information as to which molecular processes, present at diagnosis, favor tumour escape from standard-of-care treatments in cervical cancer (CC). RAIDs consortium (www.raids-fp7.eu), conducted a prospectively monitored t
Autor:
Gert Jan Fleuren, Frans A. Prins, Ekaterina S. Jordanova, Arko Gorter, Michelle Osse, J. Baptist Trimbos, Marlies Schrevel
Publikováno v:
International Journal of Oncology
International Journal of Oncology, 50(6), 1947-1954
International Journal of Oncology, 50(6), 1947-1954. Spandidos Publications
Schrevel, M, Osse, E M, Prins, F A, Trimbos, J B M Z, Fleuren, G J, Gorter, A & Jordanova, E S 2017, ' Autocrine expression of the epidermal growth factor receptor ligand heparin-binding EGF-like growth factor in cervical cancer ', International Journal of Oncology, vol. 50, no. 6, pp. 1947-1954 . https://doi.org/10.3892/ijo.2017.3980
International Journal of Oncology, 50(6), 1947-1954
International Journal of Oncology, 50(6), 1947-1954. Spandidos Publications
Schrevel, M, Osse, E M, Prins, F A, Trimbos, J B M Z, Fleuren, G J, Gorter, A & Jordanova, E S 2017, ' Autocrine expression of the epidermal growth factor receptor ligand heparin-binding EGF-like growth factor in cervical cancer ', International Journal of Oncology, vol. 50, no. 6, pp. 1947-1954 . https://doi.org/10.3892/ijo.2017.3980
In cervical cancer, the epidermal growth factor receptor (EGFR) is overexpressed in 70-90% of the cases and has been associated with poor prognosis. EGFR-based therapy is currently being explored in cervical cancer. We investigated which EGFR ligand
Autor:
Suzy Scholl, Sorin Dema, Noreen Gleeson, Michel Fabbro, Elodie Girard, Nathalie Mesgouez-Nebout, Mathieu Minsat, Fabrice Lecuru, Eleonor Rivin del Campo, Alexia Savignoni, Jean Marc Classe, Leanne de Koning, Virginie Fourchotte, Nina Samet, Anne Floquet, Pierre Gestraud, Katarina Koprivsek, Pierre Emmanuel Colombo, Roman Rouzier, Balázs Bálint, Christine Kerr, Charlotte Ngo, Heiko von der Leyen, Gemma G. Kenter, Jean Guillaume Feron, Nicolas de Saint-Jorre, Charles Coutant, Henry Zijlmans, Philippe Hupé, Pauline Wimberger, Aljosa Mandic, Els M.J.J. Berns, Philippe Morice, Goran Malenkovic, Madalin Margan, Coraline Dubot, Attila Kereszt, Pierre Fumoleau, Frédéric Guyon, Delphine Garbay, Nicolas Servant, Frédéric Marchal, Sanne Samuels, István Nagy, Maud Kamal, Marius Craina, Anne de la Rochefordiere, Peter Hillemanns, Eric Deutsch, Ekaterina S. Jordanova, Branislav Djuran, Alis Dema, Marina Popovic, Sylvain Dureau
Publikováno v:
EBioMedicine, 43, 253-260. Elsevier BV
EBioMedicine
EBioMedicine, Elsevier, 2019, 43, pp.253-260. ⟨10.1016/j.ebiom.2019.03.069⟩
EBioMedicine, 2019, 43, pp.253-260. ⟨10.1016/j.ebiom.2019.03.069⟩
Scholl, S, Popovic, M, de la Rochefordiere, A, Girard, E, Dureau, S, Mandic, A, Koprivsek, K, Samet, N, Craina, M, Margan, M, Samuels, S, Zijlmans, H, Kenter, G, Hillemanns, P, Dema, S, Dema, A, Malenkovic, G, Djuran, B, Floquet, A, Garbay, D, Guyon, F, Colombo, P E, Fabbro, M, Kerr, C, Ngo, C, Lecuru, F, Campo, E R D, Coutant, C, Marchal, F, Mesgouez-Nebout, N, Fourchotte, V, Feron, J G, Morice, P, Deutsch, E, Wimberger, P, Classe, J-M, Gleeson, N, von der Leyen, H, Minsat, M, Dubot, C, Gestraud, P, Kereszt, A, Nagy, I, Balint, B, Berns, E, Jordanova, E, Saint-Jorre, N D, Savignoni, A, Servant, N, Hupe, P, de Koning, L, Fumoleau, P, Rouzier, R & Kamal, M 2019, ' Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome ', EBioMedicine, vol. 43, pp. 253-260 . https://doi.org/10.1016/j.ebiom.2019.03.069
EBioMedicine
EBioMedicine, Elsevier, 2019, 43, pp.253-260. ⟨10.1016/j.ebiom.2019.03.069⟩
EBioMedicine, 2019, 43, pp.253-260. ⟨10.1016/j.ebiom.2019.03.069⟩
Scholl, S, Popovic, M, de la Rochefordiere, A, Girard, E, Dureau, S, Mandic, A, Koprivsek, K, Samet, N, Craina, M, Margan, M, Samuels, S, Zijlmans, H, Kenter, G, Hillemanns, P, Dema, S, Dema, A, Malenkovic, G, Djuran, B, Floquet, A, Garbay, D, Guyon, F, Colombo, P E, Fabbro, M, Kerr, C, Ngo, C, Lecuru, F, Campo, E R D, Coutant, C, Marchal, F, Mesgouez-Nebout, N, Fourchotte, V, Feron, J G, Morice, P, Deutsch, E, Wimberger, P, Classe, J-M, Gleeson, N, von der Leyen, H, Minsat, M, Dubot, C, Gestraud, P, Kereszt, A, Nagy, I, Balint, B, Berns, E, Jordanova, E, Saint-Jorre, N D, Savignoni, A, Servant, N, Hupe, P, de Koning, L, Fumoleau, P, Rouzier, R & Kamal, M 2019, ' Clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome ', EBioMedicine, vol. 43, pp. 253-260 . https://doi.org/10.1016/j.ebiom.2019.03.069
Background There is a lack of information as to which molecular processes, present at diagnosis, favor tumour escape from standard-of-care treatments in cervical cancer (CC). RAIDs consortium ( www.raids-fp7.eu ), conducted a prospectively monitored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b678774e6b5437f7345a5cf4b702ec4
https://pure.amc.nl/en/publications/clinical-and-genetic-landscape-of-treatment-naive-cervical-cancer-alterations-in-pik3ca-and-in-epigenetic-modulators-associated-with-suboptimal-outcome(97b3d668-59d1-4ab1-98f5-8a5731df51f7).html
https://pure.amc.nl/en/publications/clinical-and-genetic-landscape-of-treatment-naive-cervical-cancer-alterations-in-pik3ca-and-in-epigenetic-modulators-associated-with-suboptimal-outcome(97b3d668-59d1-4ab1-98f5-8a5731df51f7).html
Autor:
Awa A Gassama, S Samuels, Constantijne H. Mom, Anita G.M. Stam, Henry Zijlmans, Ekaterina S. Jordanova, AM Heeren, Jossie Rotman, G.G. Kenter, T.D. de Gruijl, Maaike C G Bleeker, Noëlle Pocorni
Publikováno v:
Journal for immunotherapy of cancer, 7(1):43. BioMed Central Ltd.
Journal for Immunotherapy of Cancer, 7(1):43. BioMed Central
Journal for Immunotherapy of Cancer
Heeren, AM, Rotman, J, Stam, A G M, Pocorni, N, Gassama, A, Samuels, S, Bleeker, M C G, Mom, CH, Zijlmans, H J M A A, Kenter, GG, Jordanova, ES & de Gruijl, TD 2019, ' Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels ', Journal for Immunotherapy of Cancer, vol. 7, no. 1, 43 . https://doi.org/10.1186/s40425-019-0526-z
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Journal for Immunotherapy of Cancer, 7(1):43. BioMed Central
Journal for Immunotherapy of Cancer
Heeren, AM, Rotman, J, Stam, A G M, Pocorni, N, Gassama, A, Samuels, S, Bleeker, M C G, Mom, CH, Zijlmans, H J M A A, Kenter, GG, Jordanova, ES & de Gruijl, TD 2019, ' Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint levels ', Journal for Immunotherapy of Cancer, vol. 7, no. 1, 43 . https://doi.org/10.1186/s40425-019-0526-z
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Background Cervical cancer (CxCa) is mainly a locally invading disease that metastasizes to loco-regional lymph node basins before involving distant organs in more advanced stages. Local immune potentiation of tumor-draining lymph nodes (TDLN) may th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac1b38252c80b25221cafe4432055f7
https://pure.amc.nl/en/publications/efficacy-of-pd1-blockade-in-cervical-cancer-is-related-to-a-cd8foxp3cd25-tcell-subset-with-operational-effector-functions-despite-high-immune-checkpoint-levels(c1753c5f-7e7a-4e79-b522-5b15e7156a17).html
https://pure.amc.nl/en/publications/efficacy-of-pd1-blockade-in-cervical-cancer-is-related-to-a-cd8foxp3cd25-tcell-subset-with-operational-effector-functions-despite-high-immune-checkpoint-levels(c1753c5f-7e7a-4e79-b522-5b15e7156a17).html