Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Olga Garaschuk"'
Autor:
Oleh I. Demianchuk, Nadia M. Mosiichuk, Volodymyr I. Lushchak, Oksana V. Kuzniak, Yulia V. Vasylyk, Maria M. Bayliak, Dmytro V. Gospodaryov, Olga Garaschuk, Oksana M. Sorochynska, Kenneth B. Storey
Publikováno v:
Experimental gerontology. 145
Normal brain aging is accompanied by intensification of free radical processes and compromised bioenergetics. Caloric restriction is expected to counteract these changes but the underlying protective mechanisms remain poorly understood. The present w
Publikováno v:
Cell Calcium. 94:102334
S100B is an EF-hand type Ca2+-binding protein of the S100 family, known to support neurogenesis and to promote the interactions between brain's nervous and immune systems. Here, we characterized the expression of S100B in the mouse olfactory bulb, a
Autor:
Tetiana M. Pankiv, Oksana M. Sorochynska, Dmytro V. Gospodaryov, Volodymyr I. Lushchak, Maria M. Bayliak, Yulia V. Vasylyk, Oksana V. Kuzniak, Olga Garaschuk, Kenneth B. Storey
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology, Vol 10 (2019)
Intermittent fasting is used to reduce body mass in obese adult humans and animals. However, information on the impact of one type of intermittent fasting (IF) called every-other-day feeding (EODF) on young animals is scarce. In this study, 1-month-o
Autor:
Bianca Brawek, Olga Garaschuk
Publikováno v:
Cell calcium. 64
Microglia, the innate immune cells of the brain, are becoming increasingly recognized as an important player both in the context of physiological brain function and brain pathology. To fulfill their executive functions microglia can modify their morp
Autor:
Marc Aurel Busche, Helmuth Adelsberger, Matthias Staufenbiel, Gerhard Eichhoff, Arthur Konnerth, Dorothee Abramowski, Karl-Heinz Wiederhold, Christian Haass, Olga Garaschuk
Publikováno v:
Science. 321:1686-1689
The neurodegeneration observed in Alzheimer's disease has been associated with synaptic dismantling and progressive decrease in neuronal activity. We tested this hypothesis in vivo by using two-photon Ca 2+ imaging in a mouse model of Alzheimer's dis
Autor:
Shinichi Kohsaka, Chommanad Lerdkrai, Bernd Schwendele, Olga Garaschuk, Karin Riester, Bianca Brawek, Yajie Liang
Publikováno v:
Acta neuropathologica. 127(4)
Neuroinflammation is a hallmark of Alzheimer's disease (AD) both in man and in multiple mouse models, and epidemiological studies link the use of anti-inflammatory drugs with a reduced risk of developing the disease. AD-related neuroinflammation is l
Autor:
Yury Kovalchuk, Olga Garaschuk
Publikováno v:
Cold Spring Harbor protocols. 2012(7)
This protocol describes a technique for high-resolution chloride imaging of living cells using a quinoline-based chloride (Cl−) indicator dye, MQAE (N-[6-methoxyquinolyl] acetoethyl ester). Bath-applied to acute brain slices, MQAE provides high-qua
Publikováno v:
Nature neuroscience. 8(8)
Using a new optical fiber-based approach, we demonstrate the presence of recurrent Ca(2+) transients in cortical neurons of non-anesthetized newborn mice in vivo. These Ca(2+) waves reflect the correlated activity of thousands of cells and were detec
Publikováno v:
Nature neuroscience. 3(5)
Two-photon imaging of large neuronal networks in cortical slices of newborn rats revealed synchronized oscillations in intracellular Ca2+ concentration. These spontaneous Ca2+ waves usually started in the posterior cortex and propagated slowly (2.1 m