Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sophie Stephenson"'
Autor:
Matthew A. Care, Andy C. Rawstron, Gina M. Doody, Reuben Tooze, Sophie Stephenson, Adam Davison, Mario Cocco, David R. Westhead, Darren J. Newton, Nicholas A. Barnes
Publikováno v:
The Journal of Immunology. 189:5773-5785
Plasma cells (PCs), the terminal effectors of humoral immunity, are short-lived unless supported by niche environments in which they may persist for years. No model system has linked B cell activation with niche function to allow the in vitro generat
Publikováno v:
The Journal of Immunology. 189:253-260
During cellular differentiation, mRNA transcription and translation require precise coordination. The mechanisms controlling this are not well defined. IL-21 is an important regulator of plasma cell differentiation, and it controls the master regulat
Publikováno v:
Blood. 118:2187-2187
Abstract 2187 Plasma cells, the terminal effectors of the B-cell lineage include both short- and long-lived cells. The latter persist for extended periods in the absence of cell division, supported in niche environments. No model system has successfu
Publikováno v:
Blood. 106:2207-2207
Human B lymphocyte-induced maturation protein-1 (BLIMP-1) was originally described as a repressor of the interferon-beta response to viral infection. Subsequently, the murine orthologue was identified as a regulator of plasma cell differentiation. Th