Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Won-Ha Lee"'
Autor:
Anup Bhusal, Youngpyo Nam, Donggun Seo, Md Habibur Rahman, Eun Mi Hwang, Seung‐Chan Kim, Won‐Ha Lee, Kyoungho Suk
Publikováno v:
GliaREFERENCES. 70(10)
Cathelicidin-related antimicrobial peptide (CRAMP) is an effector molecule of the innate immune system with direct antimicrobial and immunomodulatory activities; however, its role in neuroinflammatory responses and related diseases is not clearly und
Publikováno v:
Glia. 69:971-996
Diabetic peripheral neuropathy (DPN) is a common complication of uncontrolled diabetes. The pathogenesis of DPN is associated with chronic inflammation in dorsal root ganglion (DRG), eventually causing structural and functional changes. Studies on DP
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Age-related chronic inflammatory activation of microglia and their dysfunction are observed in many neurodegenerative diseases, and the potential contributions of these dysfunctional cells to neurodegeneration have been demonstrated recently. The hou
Publikováno v:
Experimental Neurobiology
Axon guidance molecules (AGMs), such as Netrins, Semaphorins, and Ephrins, have long been known to regulate axonal growth in the developing nervous system. Interestingly, the chemotactic properties of AGMs are also important in the postnatal period,
Autor:
Habibur Rahman, Won-Ha Lee, Mithilesh Kumar Jha, Hyun Kook, Inkyu Lee, Dong Ho Park, Kyoungho Suk
Publikováno v:
Journal of Neuroscience Research. 94:837-849
Pyruvate dehydrogenase (PDH) kinases (PDKs) 1-4, expressed in peripheral and central tissues, regulate the activity of the PDH complex (PDC). The PDC is an important mitochondrial gatekeeping enzyme that controls cellular metabolism. The role of PDKs
Autor:
Ri Yu, Won-Jong Oh, Jong-Heon Kim, Ho-Won Lee, Maan-Gee Lee, Jae-Hong Kim, Pan-Woo Ko, Kyoungho Suk, Won-Ha Lee, Ji-Young Jeong
Publikováno v:
Glia. 65(9)
Lipocalin-2 (LCN2) has diverse functions in multiple pathophysiological conditions; however, its pathogenic role in vascular dementia (VaD) is unknown. Here, we investigated the role of LCN2 in VaD using rodent models of global cerebral ischemia and
Publikováno v:
Journal of Neurochemistry. 117:494-503
Malignant gliomas are the most destructive type of brain cancer. In order to gain a better understanding of the molecular mechanisms of glioma cell death and survival, we previously established an alkylating agent 1, 3-bis(2-chloroethyl)-1-nitrosoure
Publikováno v:
Journal of Neurochemistry. 107:1225-1235
Glial activation and neuroinflammatory processes play an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and HIV dementia. Activated glia cells can secrete various proinflammatory cyt
Autor:
Sang-Hyun Kim, Jiyeon Ock, Hae Chul Park, Long Tai Zheng, Jaegyu Hwang, Ho-Won Lee, Maan-Gee Lee, Won-Ha Lee, Kyoungho Suk
Publikováno v:
Neuropharmacology. 55:826-834
Glial activation and neuroinflammatory processes play an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and HIV dementia. Activated glial cells can secrete various proinflammatory cy
Autor:
Eui Kyun Park, Kyoungho Suk, Sang-Hyun Kim, Won-Ha Lee, Minchul Seo, Sangseop Kim, Long Tai Zheng
Publikováno v:
Journal of Neuroscience Research. 86:1087-1095
Discoidin domain receptor 1 (DDR1) is a nonintegrin collagen receptor tyrosine kinase with an extracellular domain homologous to discoidin 1 of a soil-living amoeba Dictyostelium discoideum. We have previously demonstrated that DDR1 mediates collagen