Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Won-Ha Lee"'
Autor:
Anup Bhusal, Youngpyo Nam, Donggun Seo, Md Habibur Rahman, Eun Mi Hwang, Seung‐Chan Kim, Won‐Ha Lee, Kyoungho Suk
Publikováno v:
GliaREFERENCES. 70(10)
Cathelicidin-related antimicrobial peptide (CRAMP) is an effector molecule of the innate immune system with direct antimicrobial and immunomodulatory activities; however, its role in neuroinflammatory responses and related diseases is not clearly und
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Age-related chronic inflammatory activation of microglia and their dysfunction are observed in many neurodegenerative diseases, and the potential contributions of these dysfunctional cells to neurodegeneration have been demonstrated recently. The hou
Autor:
Ri Yu, Won-Jong Oh, Jong-Heon Kim, Ho-Won Lee, Maan-Gee Lee, Jae-Hong Kim, Pan-Woo Ko, Kyoungho Suk, Won-Ha Lee, Ji-Young Jeong
Publikováno v:
Glia. 65(9)
Lipocalin-2 (LCN2) has diverse functions in multiple pathophysiological conditions; however, its pathogenic role in vascular dementia (VaD) is unknown. Here, we investigated the role of LCN2 in VaD using rodent models of global cerebral ischemia and
Publikováno v:
Journal of Neurochemistry. 107:1225-1235
Glial activation and neuroinflammatory processes play an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and HIV dementia. Activated glia cells can secrete various proinflammatory cyt
Autor:
Sang-Hyun Kim, Jiyeon Ock, Hae Chul Park, Long Tai Zheng, Jaegyu Hwang, Ho-Won Lee, Maan-Gee Lee, Won-Ha Lee, Kyoungho Suk
Publikováno v:
Neuropharmacology. 55:826-834
Glial activation and neuroinflammatory processes play an important role in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and HIV dementia. Activated glial cells can secrete various proinflammatory cy
Autor:
Eui Kyun Park, Kyoungho Suk, Sang-Hyun Kim, Won-Ha Lee, Minchul Seo, Sangseop Kim, Long Tai Zheng
Publikováno v:
Journal of Neuroscience Research. 86:1087-1095
Discoidin domain receptor 1 (DDR1) is a nonintegrin collagen receptor tyrosine kinase with an extracellular domain homologous to discoidin 1 of a soil-living amoeba Dictyostelium discoideum. We have previously demonstrated that DDR1 mediates collagen
Publikováno v:
Journal of Neuroinflammation, Vol 9, Iss 1, p 149 (2012)
JOURNAL OF NEUROINFLAMMATION(9)
Journal of Neuroinflammation
JOURNAL OF NEUROINFLAMMATION(9)
Journal of Neuroinflammation
Background Plasminogen activator inhibitor type 1 (PAI-1) is the primary inhibitor of urokinase type plasminogen activators (uPA) and tissue type plasminogen activators (tPA), which mediate fibrinolysis. PAI-1 is also involved in the innate immunity
Publikováno v:
Journal of neuroscience research. 88(10)
Glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) is a member of the tumor necrosis factor superfamily (TNFSF) and is known to act as a costimulator in the immune system by binding to GITR. GITRL is expressed
Autor:
Won-Ha Lee, Wan Sung Choi, Inkyeom Kim, Jaeyoon Jeong, Jiyeon Ock, Kyoungho Suk, Sang-Hyun Kim
Publikováno v:
Journal of neuroscience research. 85(9)
Hypoxia is an important biological signal that regulates a wide variety of physiological responses. At the same time, hypoxia is involved in multiple pathological situations. In particular, hypoxia is closely associated with neural injury in the brai
Autor:
Eun Jung Park, Dong-Kug Choi, Jiyeon Ock, Sang-Hyun Kim, Won-Ha Lee, Inkyeom Kim, Heasuk Lee, Kyoungho Suk, Sangseop Kim
Publikováno v:
Journal of neurochemistry. 98(3)
Neuropeptides are short-chain peptides found in brain tissue, some of which function as neurotransmitters and others as hormones. Neuropeptides may directly or indirectly modulate glial functions in the CNS. In the present study, effects of various n