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Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 319:E1112-E1120
Neuronal control of the energy homeostasis requires the arcuate nucleus of the hypothalamus. This structure integrates peripheral and central signals concerning the energy state of the body. It comprises two populations of neurons releasing anorexige
Autor:
Igor Khaliulin, Frantisek Kolar, M-Saadeh Suleiman, Leonid N. Maslov, Yury B. Lishmanov, N. V. Naryzhnaya, Sergey Y Tsibulnikov
Publikováno v:
Naryzhnaya, N V, Khaliulin, I, Lishmanov, Y B, Suleiman, M-S, Tsibulnikov, S, Kolar, F & Maslov, L N 2019, ' Participation of opioid receptors in the cytoprotective effect of chronic normobaric hypoxia ', Physiological Research, vol. 68, no. 2, pp. 245-253 . https://doi.org/10.33549/physiolres.933938
We studied the role of the delta, micro, and kappa opioid receptor (OR) subtypes in the cardioprotective effect of chronic continuous normobaric hypoxia (CNH) in the model of acuteanoxia-reoxygenation of isolated cardiomyocytes. Adaptation of rats to
Autor:
Jolanta Murgott, Stephan Leisengang, Joachim Roth, Franz Nürnberger, Rüdiger Gerstberger, Daniela Ott, Christoph Rummel
Publikováno v:
Pflugers Archiv
One maladaptive consequence of inflammatory stimulation of the afferent somatosensory system is the manifestation of inflammatory pain. We established and characterized a neuroglial primary culture of the rat superficial dorsal horn (SDH) of the spin
Autor:
Matias Estaras, Jose M. Mateos, Gerardo Blanco, Ginés M. Salido, Fernando J. Peña, Daniel Vara, Antonio González, V. Roncero, Diego Lopez, Miguel Fernandez-Bermejo, Jose A. Tapia
Publikováno v:
Journal of physiology and biochemistry. 76(2)
In this study, the effects of melatonin (1 μM–1 mM) on pancreatic stellate cells (PSC) have been examined. Cell viability and proliferation, caspase-3 activation, and the expression of cyclin A and cyclin D were analyzed. Our results show that mel
Autor:
Carolina Demarchi Munhoz, Ana Paula Cremasco Takano, Nathalia Senger, Maria Luiza Morais Barreto-Chaves
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 470:549-558
We have previously demonstrated that calcium-binding protein S100A8 and myeloid differentiation factor-88 (MyD88) are important mediators of nuclear transcription factor kappa-B (NF-κB) activation in cardiomyocytes and that signalling molecules are
Publikováno v:
Scopus-Elsevier
In ischemic/reperfusion (I/R) injured hearts, severe oxidative stress occurs and is associated with intracellular calcium (Ca(2+)) overload. Glucagon-Like Peptide-1 (GLP-1) analogues have been shown to exert cardioprotection in I/R heart. However, th
Publikováno v:
Clinical and experimental pharmacologyphysiologyREFERENCES. 46(12)
It has been shown that both nilotinib as a tyrosine kinase inhibitor, and atorvastatin as a rho-kinase inhibitor, have antifibrotic effects. Therefore, considering the relationship between these two pathways, this study aimed to investigate the effec
Publikováno v:
Neurosci Bull
In the present study, we investigated the mechanisms underlying the mediation of iron transport by L-type Ca(2+) channels (LTCCs) in primary cultured ventral mesencephalon (VM) neurons from rats. We found that co-treatment with 100 µmol/L FeSO(4) an
Publikováno v:
General physiology and biophysics. 38(4)
Non-alcoholic fatty liver disease and its complications are frequent causes of liver-related morbidity and mortality. Incretin glucagon-like peptide-1 (GLP-1) affects liver functions and metabolism. Although GLP-1 analogues are widely used in clinica
Autor:
Hiroya Mizutani, Hisao Yamamura, Makoto Muramatsu, Yuji Imaizumi, Yumiko Hagihara, Yoshiaki Suzuki
Publikováno v:
American Journal of Physiology-Cell Physiology. 310:C740-C747
The pineal glands regulate circadian rhythm through the synthesis and secretion of melatonin. The stimulation of nicotinic acetylcholine receptor due to parasympathetic nerve activity causes an increase in intracellular Ca2+concentration and eventual