Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hsun–Ming Chang"'
Publikováno v:
The FASEB Journal. 34:16129-16143
Locally produced in human granulosa cells of the developing follicle, bone morphogenetic protein 2 (BMP2) plays a crucial role in the regulation of ovarian folliculogenesis and luteal formation. Brain-derived neurotrophic factor (BDNF) is an intraova
Publikováno v:
The FASEB Journal. 35
Serine protease inhibitor-E2 (SERPINE2) is highly expressed in the granulosa cells of growing follicles and the dynamic changes in SERPINE2 expression are correlated with follicular development and ovulation in several mammals, including mice, cattle
Publikováno v:
Cellular signalling. 63
Hyaluronan serves as a structural component of ovarian follicles, and hyaluronan-mediated signaling cascades lead to follicular development, oocyte maturation, and ovulation. Transforming growth factor-β (TGF-β1) is highly expressed in human oocyte
Autor:
Peter C.K. Leung, Zhengao Sun, Hsun-Ming Chang, Fang Lian, Yung-Ming Lin, Yuyin Yi, Hai-Cui Wu
Publikováno v:
Molecular and cellular endocrinology. 498
Connexin 43 (Cx43)-coupled gap junctions in granulosa cells play an important role in follicular development, oocyte maturation, and corpus luteum maintenance. Bone morphogenetic protein 6 (BMP6) is highly expressed in human oocytes and granulosa cel
Publikováno v:
Molecular and Cellular Endocrinology. 505:110731
In the mammalian ovary, the proteolysis of the extracellular matrix is dynamically regulated by plasminogen activator and plasminogen activator inhibitor (PAI), and it is a critical event that influences various physiological and pathological process
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:E375-E386
Granulosa cell-derived activins play important roles in the regulation of ovarian functions. To date, there is limited information pertaining to the intracellular regulation, assembly, and secretion of endogenous activin A in human granulosa cells.Th
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E1922-E1932
Exerting a broad range of biological effects in various tissues, activins are homo- or heterodimers of activin/inhibin β-subunits (βA, βB, βC, and βE in humans). Although activins A (βAβA), B (βBβB), AB (βAβB), and AC (βAβC) have been de
Publikováno v:
Molecular and Cellular Endocrinology. 493:110485
As one of the members of the transforming growth factor-β (TGF-β) superfamily, activin A plays an important role in regulating follicular development and oocyte maturation. Pentraxin 3 (PTX3) is the key component that promotes the process of cumulu
Autor:
Christian Klausen, Jung-Chien Cheng, Peter C.K. Leung, Hsun-Ming Chang, Congjian Xu, Yingtao Liu
Publikováno v:
Reproduction (Cambridge, England). 152(4)
Lysyl oxidase (LOX) is the key enzyme involved in the crosslinking of collagen and elastin that is essential for the formation of extracellular matrix (ECM). LOX-mediated ECM remodeling plays a critical role in follicle development, oocyte maturation
Autor:
Jung-Chien Cheng, Ying Fang, Xiaokui Yang, Hsun-Ming Chang, Christian Klausen, Peter C.K. Leung
Publikováno v:
Reproduction (Cambridge, England). 152(3)
Lysyl oxidase (LOX), a key enzyme in the formation and stabilization of the extracellular matrix, is expressed in granulosa cells and plays a critical role in the regulation of granulosa cell differentiation, oocyte maturation and ovulation. To date,