Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Noriko Koizumi"'
Autor:
Naoki Okumura, Ursula Schlötzer-Schrehardt, Noriko Koizumi, Andreas Gießl, Friedrich E. Kruse, Mark A. Greiner, Shigeru Kinoshita, Hannah Schondorf, Matthias Zenkel, Theofilos Tourtas, Maria Strunz, Gregory A. Schmidt, Heather da Silva
Publikováno v:
American Journal of Ophthalmology. 224:185-199
Purpose Rho-associated kinase (ROCK) inhibitors have been successfully used as a rescue strategy in eyes that failed to clear after descemetorhexis without endothelial graft for treatment of Fuchs endothelial corneal dystrophy (FECD). The functional
Autor:
Naoya Ishida, Naoki Okumura, Keitaro Kobayashi, Noriko Koizumi, Tomoyuki Hiroyasu, Satoru Hiwa, Takato Kagami
Publikováno v:
Cornea. 37:1572-1578
PURPOSE To develop software to evaluate the fibroblastic morphological changes in cultured human corneal endothelial cells (HCECs) as a quality control measure for use in tissue engineering therapy. METHODS Software was designed to recognize cell bor
Autor:
Shigeru Kinoshita, Makiko Nakahara, Junji Hamuro, Naoki Okumura, Ryota Inoue, Kazuya Kakutani, Noriko Koizumi
Publikováno v:
Cornea. 36:988-994
The aim of this study was to evaluate which amino acid(s) among the 20 standard protein amino acids is indispensable for the survival of cultured human corneal endothelial cells (HCECs).HCECs were cultured in amino acid screening media that were miss
Publikováno v:
Cornea. 33:S25-S31
Corneal endothelial dysfunction accompanied by visual disturbance is a primary indication for corneal endothelial transplantation. However, despite the value and potential of endothelial graft surgery, a strictly pharmacological approach for treating
Autor:
Naresh Polisetti, Lydia Sorokin, Naoki Okumura, Noriko Koizumi, Shigeru Kinoshita, Friedrich E. Kruse, Ursula Schlötzer-Schrehardt
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Optimization of culture conditions for human limbal epithelial stem/progenitor cells (LEPC) that incorporate the in vivo cell-matrix interactions are essential to enhance LEPC ex vivo-expansion and transplantation efficiency. Here, we investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c92e604953f8537d4d25a863ccae0600
https://opus4.kobv.de/opus4-fau/files/9548/Polisetti_laminin-511.pdf
https://opus4.kobv.de/opus4-fau/files/9548/Polisetti_laminin-511.pdf
Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Corneal Endothelial Cell Proliferation
Publikováno v:
Investigative Opthalmology & Visual Science. 59:4218
Purpose We have performed clinical research on cell-based therapy for corneal endothelial decompensation since 2013. The purpose of this study was to investigate the usefulness of a p38 MAPK inhibitor for promoting proliferation of human corneal endo
Autor:
Naoki Okumura, Shigeru Kinoshita, Hiroko Nakagawa, Yugo Okazaki, Ryota Inoue, Noriko Koizumi, Shinichiro Nakano
Publikováno v:
Investigative ophthalmologyvisual science. 56(10)
PURPOSE The purpose of this study was to investigate the feasibility of using Rho-associated kinase (ROCK) inhibitor eye drops for treating severe corneal endothelial damage due to surgical invasion. METHODS A rabbit corneal endothelial damage model
Autor:
Shigeru Kinoshita, Naoki Okumura, Morio Ueno, Hiroaki Takahashi, Junji Hamuro, Noriko Koizumi, Yuji Sakamoto
Publikováno v:
Cornea. 30:S54-S59
Corneal endothelial cells (CECs) show poor regenerative ability in humans, and noncompensatory damage of CECs causes irreversible corneal haziness in cases of bullous keratopathy. Although corneal transplantations provide considerable clinical benefi
Enhancement of corneal endothelium wound healing by Rho-associated kinase (ROCK) inhibitor eye drops
Autor:
Morio Ueno, Hiroaki Takahashi, Naoki Okumura, Noriko Koizumi, Yuji Sakamoto, K. Hirata, Ryuzo Torii, Junji Hamuro, Shigeru Kinoshita
Publikováno v:
British Journal of Ophthalmology. 95:1006-1009
Aim To demonstrate the efficacy of Rho-associated kinase (ROCK) inhibitor Y-27632 for corneal endothelial wound healing both in in vitro and in vivo models. Methods As an in vitro model, cultivated cynomolgus monkey corneal endothelial cells were scr
Autor:
Shigeru Kinoshita, Leanne J. Cooper, Naoki Okumura, Yuji Sakamoto, Yuriko Ban, Ryuzo Torii, Hidetoshi Tanioka, Noriko Koizumi, Hideaki Tsuchiya
Publikováno v:
Cornea. 27:S48-S55
PURPOSE To review our attempt to devise a method of cultivated corneal endothelial transplantation using primates in which corneal endothelium, like that of humans, has low proliferative ability. METHODS Monkey corneal endothelial cells (MCECs) were