Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jee H. Jung"'
Autor:
Bin Xiao, Mingzhi Su, Eun La Kim, Jongki Hong, Hae Young Chung, Hyung Sik Kim, Jun Yin, Jee H. Jung
Publikováno v:
Marine Drugs, Vol 12, Iss 2, Pp 926-939 (2014)
A series of N-substituted phthalimide derivatives were synthesized based on a pharmacophore study of paecilocin A (a natural PPAR-γ agonist) and synthetic leads. The introduction of hydrophilic and hydrophobic groups to the phthalimide skeleton yiel
Externí odkaz:
https://doaj.org/article/79714100cf624a04914f82ece191b0ed
Autor:
Jee H. Jung, Nam Deuk Kim, Hae Young Chung, Hongsuk Suh, Min Jeong Kim, Bokyung Sung, Dong Hwan Kim
Publikováno v:
Oncology Reports. 37:281-288
Resveratrol, a polyphenolic compound, is a naturally occurring phytochemical and is found in a variety of plants, including grapes, berries and peanuts. It has gained much attention for its potential anticancer activity against various types of human
Autor:
Zhiran Ju, Jiafu Cao, Young-Suk Jung, Mingzhi Su, Eun La Kim, Chang-Hao Zhao, Jee H. Jung, Dan-Dan Li
Publikováno v:
Marine Drugs
Volume 18
Issue 9
Marine Drugs, Vol 18, Iss 445, p 445 (2020)
Volume 18
Issue 9
Marine Drugs, Vol 18, Iss 445, p 445 (2020)
Microtubules play a crucial role in mitosis and are attractive targets for cancer therapy. Recently, we isolated viriditoxin, a cytotoxic and antibacterial compound, from a marine fungus Paecilomyces variotii. Viriditoxin has been reported to inhibit
Publikováno v:
International Journal of Medical Sciences
Objective: Tamoxifen is currently used for the treatment of estrogen receptor-positive breast cancer patients, but acquired resistance to tamoxifen is a critical problem in breast cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is a prototype
Autor:
In Su Kim, Jee H. Jung, Sungpil Yoon, Wahn Soo Choi, Eui Kyung Lee, Jaewon Lee, Seong Jin Kim, Ki-Tae Ha, Byung Mu Lee, Umasankar De, Eun Young Park, Do Hyun Kim, Hyung Sik Kim, Kyeong Seok Kim, Youngwoo Woo, Hyung Ryong Moon
Publikováno v:
International Journal of Biological Sciences
The sirtuins (SIRTs), a family of NAD+-dependent class III histone deacetylase, are involved in various biological processes including cell survival, division, senescence, and metabolism via activation of the stress-response pathway. Recently, inhibi
Autor:
Hae Young Chung, Tae Hyung Kim, Hyung Sik Kim, Mee Young Ahn, Ji Hye Park, Sungpill Yoon, Jee H. Jung, Keon Wook Kang, Hyung Ryong Moon, Jaewon Lee
Publikováno v:
Investigational New Drugs. 30:1887-1898
Acquired resistance to tamoxifen (Tam) is a critical problem in breast cancer therapy. Therefore, new potential strategies for Tam-resistant breast cancer are needed recently. In this study, we synthesized a novel histone deacetylase (HDAC) inhibitor
Autor:
Mingzhi Su, Jongki Hong, Bin Xiao, Jee H. Jung, Eun La Kim, Jun Yin, Hyung Sik Kim, Hae Young Chung
Publikováno v:
MARINE DRUGS(12): 2
Marine Drugs
Marine Drugs; Volume 12; Issue 2; Pages: 926-939
Marine Drugs, Vol 12, Iss 2, Pp 926-939 (2014)
Marine Drugs
Marine Drugs; Volume 12; Issue 2; Pages: 926-939
Marine Drugs, Vol 12, Iss 2, Pp 926-939 (2014)
A series of N-substituted phthalimide derivatives were synthesized based on a pharmacophore study of paecilocin A (a natural PPAR-γ agonist) and synthetic leads. The introduction of hydrophilic and hydrophobic groups to the phthalimide skeleton yiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62956113064864b7a66efb69e0130d5
http://open-repository.kisti.re.kr/cube/handle/open_repository/485551.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/485551.do
Autor:
Byung Mu Lee, Hae Young Chung, Yu Jin Shin, A Jin Won, Jee H. Jung, Tae Hyung Kim, Wahn Soo Choi, Hyung Sik Kim
Publikováno v:
Biochimica et biophysica acta. 1840(1)
Background Multidrug resistance is a major problem in the treatment of breast cancer, and a number of studies have attempted to find an efficient strategy with which to overcome it. In this study, we investigate the synergistic anticancer effects of
Autor:
Wahn Soo Choi, Tae Hyung Kim, Byung Mu Lee, Kyuing Sil Yoon, Jing Wang, Hyung Sik Kim, Jee H. Jung, Jaewon Lee, Sungpil Yoon, Mee Young Ahn
Publikováno v:
International journal of oncology. 41(3)
Sirtuins (SIRTs), NAD+-dependent class III histone deacetylases (HDACs), play an important role in the regulation of cell division, survival and senescence. Although a number of effective SIRT inhibitors have been developed, little is known about the
Publikováno v:
International Journal of Oncology. 38
An anti-inflammatory enone fatty acid, (E)-9-oxooctadec-10-enoic acid (C10), was previously isolated from red alga (Gracilaria verrucosa). Of the many cellular signaling pathways activated in response to the inflammatory stimulus, lipopolysaccharide,