Zobrazeno 1 - 2
of 2
pro vyhledávání: '"G. Wei Xu"'
Autor:
Neil MacLean, Shawn Brennan, Adam C. Smith, Rose Hurren, Allison Berger, Xiaoming Wang, Razq Hakem, Marcela Gronda, Mark D. Minden, Sara Farshchi Zarabi, Simon Kavanagh, Tary Traore, G. Wei Xu, Aaron D. Schimmer, Emil F. Pai, Samir H. Barghout, Ondrej Halgas, Michael Milhollen, Marc L. Hyer, Parasvi S. Patel, Danny V. Jeyaraju
Publikováno v:
Leukemia. 33:37-51
Acute myeloid leukemia (AML) is an aggressive hematologic malignancy for which new therapeutic approaches are required. One such potential therapeutic strategy is to target the ubiquitin-like modifier-activating enzyme 1 (UBA1), the initiating enzyme
Autor:
Xiaoming Li, Marko Skrtic, Reza Beheshti Zavareh, Sirano Dhe-Paganon, Tabitha E. Wood, John C. Reed, Marcela Gronda, Derek Wong, Neil MacLean, Rose Hurren, Xinliang Mao, Troy Ketela, Jason Moffat, Meenakshi Venkatesan, David R. Rose, G. Wei Xu, Xiaoming Wang, Robert A. Batey, Mohsin Ali, Aaron D. Schimmer
The proteasomal pathway of protein degradation involves 2 discrete steps: ubiquitination and degradation. Here, we evaluated the effects of inhibiting the ubiquitination pathway at the level of the ubiquitin-activating enzyme UBA1 (E1). By immunoblot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167fe70a4f879e46c72969abe6914960
https://europepmc.org/articles/PMC2920204/
https://europepmc.org/articles/PMC2920204/