Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Balázs Győrffy"'
Autor:
Iris Kahl, Julian Mense, Christopher Finke, Anna‐Lena Boller, Clara Lorber, Balázs Győrffy, Burkhard Greve, Martin Götte, Nancy A Espinoza‐Sánchez
Publikováno v:
Journal of cellular biochemistryREFERENCES. 123(3)
Breast cancer is the third most common type of cancer diagnosed. Cell cycle is a complex but highly organized and controlled process, in which normal cells sense mitogenic growth signals that instruct them to enter and progress through their cell cyc
Autor:
Kei-ichiro Arimoto, Leo J.Y. Kim, Balázs Győrffy, Klaus-Peter Knobeloch, Dong-Er Zhang, Hua Cheng, Christoph Burkart, Xiang-Dong Fu, Jeremy N. Rich, Hu Cang, Jun-Bao Fan, Yu Zhou, Hui-Zhong Xu, Ming Yan, Sayuri Miyauchi, Dan Liu
Publikováno v:
Cancer Discov
Type I interferons (IFN), which activate many IFN-stimulated genes (ISG), are known to regulate tumorigenesis. However, little is known regarding how various ISGs coordinate with one another in developing antitumor effects. Here, we report that the I
Autor:
Jing Chen, Liqing Li, Cai Huang, Haining Zhu, Vesa P. Hytönen, Olli T. Pentikäinen, Sampo Kukkurainen, Zbigniew Baster, Zenon Rajfur, Balázs Győrffy
Publikováno v:
The FASEB Journal. 34:2227-2237
Cyanidin-3-glucoside (C3G) is a natural pigment, found in many colorful fruits and vegetables. It has many health benefits, including anti-inflammation, cancer prevention, and anti-diabetes. Although C3G is assumed to be an antioxidant, it has been r
Autor:
Chan-Gi Pack, Kum Kum Khanna, Prahlad V. Raninga, Seong-il Eyun, Gordon B. Mills, Young Ha Kim, Balázs Győrffy, Seong-Jin Kim, Myoung-Hee Kang, Hee Dong Han, Yun Yong Park, Jin Sung Ju, Hee Jin Lee, Yong Shin, Ji Won Eun, Gyungyub Gong
Publikováno v:
Theranostics
Breast cancer (BC) is one of the most common cancers in women. TNBC (Triple-negative breast cancer) has limited treatment options and still lacks viable molecular targets, leading to poor outcomes. Recently, RNA-binding proteins (RBPs) have been show
Autor:
Gary Middleton, Matthew Pugh, Andrew D Beggs, Maha Ibrahim, Sundaresan Rajesh, Balázs Győrffy, Chris Tselepis, Regina Andrijes, Rahul K Hejmadi, Michael Overduin, Vera Novitskaya, Fedor Berditchevski
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tetraspanin protein (Tspan6) is a member of the tetraspanin family. Using a combination of in vitro and in vivo assays, we demonstrate that Tspan6 functions as a tumor suppressor in colorectal cancer (CRC) by attenuating the epidermal gr
Autor:
Yuta Yanagihara, Balázs Győrffy, Hiroyuki Iio, Shuhei Yoshida, Yohei Miyagi, Takeshi Kishida, Noritaka Saeki, Aoi Ikedo, Takashi Saika, Iori Sakakibara, Tadahiko Kikugawa, Yoshiyasu Nakamura, Yoichiro Okubo, Yuuki Imai, Yuichiro Sawada
Publikováno v:
International Journal of Cancer. 146:1369-1382
The prognosis of patients with progressive prostate cancers that are hormone refractory and/or have bone metastasis is poor. Multiple therapeutic targets to improve prostate cancer patient survival have been investigated, including orphan GPCRs. In o
Autor:
Ingrid Torregroza, Jude M. Phillip, Leandro Cerchietti, Shao Ning Yang, Rossella Marullo, Tharu M. Fernando, Todd Evans, Haelee Ahn, Geoffrey Lundell-Smith, Ari Melnick, Balázs Győrffy, Masayuki Hirano, Benet Pera Gresely, Gilbert G. Privé
Publikováno v:
Cancer Discov
Several lines of evidence link the canonical oncogene BCL6 to stress response. Here we demonstrate that BCL6 evolved in vertebrates as a component of the HSF1-driven stress response, which has been co-opted by the immune system to support germinal ce
Autor:
Leslie Cope, Saraswati Sukumar, Helen Sadik, Xian C. Zhou, Soonweng Cho, Athira Narayan, Vanessa F. Merino, Balázs Győrffy, C. Conover Talbot, Nguyen Nguyen, Zhe Zhang
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-14 (2018)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background A combination of entinostat, all-trans retinoic acid, and doxorubicin (EAD) induces cell death and differentiation and causes significant regression of xenografts of triple-negative breast cancer (TNBC). Methods We investigated the mechani
Autor:
Richard E. Beatson, Ana C. Parente-Pereira, Leena Halim, Domenico Cozzetto, Caroline Hull, Lynsey M. Whilding, Olivier Martinez, Chelsea A. Taylor, Jana Obajdin, Kim Ngan Luu Hoang, Benjamin Draper, Ayesha Iqbal, Tom Hardiman, Tomasz Zabinski, Francis Man, Rafael T.M. de Rosales, Jinger Xie, Fred Aswad, Daniela Achkova, Chung-Yang Ricardo Joseph, Sara Ciprut, Antonella Adami, Helge G. Roider, Holger Hess-Stumpp, Balázs Győrffy, Jelmar Quist, Anita Grigoriadis, Anette Sommer, Andrew N.J. Tutt, David M. Davies, John Maher
Publikováno v:
Cell Reports Medicine
Summary Despite its role in cancer surveillance, adoptive immunotherapy using γδ T cells has achieved limited efficacy. To enhance trafficking to bone marrow, circulating Vγ9Vδ2 T cells are expanded in serum-free medium containing TGF-β1 and IL-
Autor:
Ferhat Alkan, Anna G. Manjón, Balázs Győrffy, William J. Faller, Selçuk Yavuz, Ben Morris, Bram van den Broek, Stefan Prekovic, Mark Buijs, Liesbeth Hoekman, Joana Silva, Karin E. de Visser, Hans Teunissen, Tesa M. Severson, Theofilos Chalkiadakis, Wilbert Zwart, Donna O. Debets, Max D. Wellenstein, Anne Huber, René H. Medema, Alejandro Barrera, Elzo de Wit, Isabel Mayayo-Peralta, Karianne Schuurman, Timothy E. Reddy, Cor Lieftink, Maarten Altelaar, Roderick L. Beijersbergen, Jos Jonkers, Kim Monkhorst
Publikováno v:
Nature Communications
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications, 12(1):4360. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications, 12(1):4360. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The glucocorticoid receptor (GR) regulates gene expression, governing aspects of homeostasis, but is also involved in cancer. Pharmacological GR activation is frequently used to alleviate therapy-related side-effects. While prior studies have shown G