Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jessica L. Bell"'
Autor:
Jessica L. Bell, Andrew J. Haak, Cheryl E. Rockwell, Yajing Ji, Scott D. Larsen, Monique Verhaegen, Melanie A. Krook, Kathryn M. Appleton, Susan M. Wade, Sean A. Misek, Erika M. Lisabeth, Merlin Airik, Elizabeth R. Lawlor, Richard R. Neubig
Publikováno v:
Molecular Cancer Therapeutics. 16:193-204
Melanoma is the most dangerous form of skin cancer with the majority of deaths arising from metastatic disease. Evidence implicates Rho-activated gene transcription in melanoma metastasis mediated by the nuclear localization of the transcriptional co
Publikováno v:
Cell Cycle
Neuroblastoma is the most common solid tumor in childhood and represents 15% of all children's cancer deaths. We have previously demonstrated that tripartite motif 16 (TRIM16), a member of the RING B-box coiled-coil (RBCC)/tripartite totif (TRIM) pro
Autor:
Jessica L. Bell, Marcell Lederer, Britta Mühleck, Kristin Wächter, Nikolaos Pazaitis, Marcel Köhn, Stefan Hüttelmaier
Publikováno v:
Cellular and Molecular Life Sciences
The insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1, IGF2BP2, IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies have shown that these proteins act in various important aspects of cell fu
Autor:
James S. Wilmott, Selina K. Sutton, A Malyukova, Glenn M. Marshall, Patrick Y. Kim, Jessica L. Bell, Carla D’andreti, Jessica Koach, Charlotte M. Proby, Eric Sekyere, Anne M. Cunningham, Richard A. Scolyer, Michelle Haber, Murray D. Norris, Maria Kavallaris, Belamy B. Cheung, Irene M. Leigh, Owen Tan, Gary M. Halliday, Caroline L. Cooper
Publikováno v:
The Journal of Pathology
Retinoid therapy is used for chemo-prevention in immuno-suppressed patients at high risk of developing skin cancer. The retinoid signalling molecule, tripartite motif protein 16 (TRIM16), is a regulator of keratinocyte differentiation and a tumour su
Autor:
Eric Sekyere, Anne M. Cunningham, Patrick Y. Kim, A Malyukova, Jessica Koach, Belamy B. Cheung, Jessica L. Bell, Wayne Thomas, Tao Liu, Maria Kavallaris, Murray D. Norris, Vivienne Tobias, Glenn M. Marshall, Michelle Haber, Owen Tan
Publikováno v:
Oncogene
The family of tripartite-motif (TRIM) proteins are involved in diverse cellular processes, but are often characterized by critical protein-protein interactions necessary for their function. TRIM16 is induced in different cancer types, when the cancer
Autor:
Susan M. Wade, Andrew J. Haak, Paul D. Kirchhoff, Jessica L. Bell, Scott D. Larsen, Richard R. Neubig
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(13)
CCG-1423 (1) is a novel inhibitor of Rho/MKL1/SRF-mediated gene transcription that inhibits invasion of PC-3 prostate cancer cells in a Matrigel model of metastasis. We recently reported the design and synthesis of conformationally restricted analogs