Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Guillaume, Lenoir"'
Autor:
Thibaud Dieudonné, Sara Abad Herrera, Michelle Juknaviciute Laursen, Maylis Lejeune, Charlott Stock, Kahina Slimani, Christine Jaxel, Joseph A Lyons, Cédric Montigny, Thomas Günther Pomorski, Poul Nissen, Guillaume Lenoir
Publikováno v:
Dieudonné, T, Herrera, S A, Laursen, M J, Lejeune, M, Stock, C, Slimani, K, Jaxel, C, Lyons, J A, Montigny, C, Pomorski, T G, Nissen, P & Lenoir, G 2022, ' Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders ', eLife, vol. 11, e75272 . https://doi.org/10.7554/eLife.75272
eLife
eLife, 2022, 11, pp.e75272. ⟨10.7554/eLife.75272⟩
eLife
eLife, 2022, 11, pp.e75272. ⟨10.7554/eLife.75272⟩
P4-ATPases flip lipids from the exoplasmic to the cytosolic leaflet, thus maintaining lipid asymmetry in eukaryotic cell membranes. Mutations in several human P4-ATPase genes are associated with severe diseases, for example in ATP8B1 causing progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c35e98627e4caef8dc5e2902d3fe6a2
https://curis.ku.dk/ws/files/311880135/elife_75272_v3.pdf
https://curis.ku.dk/ws/files/311880135/elife_75272_v3.pdf
Publikováno v:
BBA-Biochimica et Biophysica Acta
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. 〈10.1016/j.bbalip.2015.12.020〉
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
Montigny, C, Lyons, J, Champeil, P, Nissen, P & Lenoir, G 2016, ' On the molecular mechanism of flippase-and scramblase-mediated phospholipid transport ', B B A-Molecular and Cell Biology of Lipids, vol. 1861, no. 8, Part B . https://doi.org/10.1016/j.bbalip.2015.12.020
BBA-Biochimica et Biophysica Acta, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. 〈10.1016/j.bbalip.2015.12.020〉
BBA-Biochimica et Biophysica Acta, Elsevier, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
Montigny, C, Lyons, J, Champeil, P, Nissen, P & Lenoir, G 2016, ' On the molecular mechanism of flippase-and scramblase-mediated phospholipid transport ', B B A-Molecular and Cell Biology of Lipids, vol. 1861, no. 8, Part B . https://doi.org/10.1016/j.bbalip.2015.12.020
BBA-Biochimica et Biophysica Acta, 2016, pp.767-83. ⟨10.1016/j.bbalip.2015.12.020⟩
International audience; Phospholipid flippases are key regulators of transbilayer lipid asymmetry in eukaryotic cell membranes, critical to many trafficking and signaling pathways. P4-ATPases, in particular, are responsible for the uphill transport o
Autor:
Carole Gauron, Martin Picard, Chikashi Toyoshima, Philippe Champeil, Guillaume Lenoir, Cédric Montigny
Publikováno v:
Biochemistry. 46:15162-15174
Ca2+-free crystals of sarcoplasmic reticulum Ca2+-ATPase have, up until now, been obtained in the presence of inhibitors such as thapsigargin (TG), bound to the transmembrane region of this protein. Here, we examined the consequences of such binding
Publikováno v:
Current Opinion in Chemical Biology. 11:654-661
Membrane lipid asymmetry influences a multitude of cellular functions, including membrane vesiculation, cell division, and lifespan. Most cells retain the bulk of aminophospholipids to the cytosolic membrane leaflet by means of ATP-fuelled flippases
Autor:
Joost C. M. Holthuis, Guillaume Lenoir
Publikováno v:
Current biology : CB. 14(21)
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