Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Simon Peter Williams"'
Autor:
Annie, Ogasawara, James R, Kiefer, Herman, Gill, Eugene, Chiang, Shravan, Sriraman, Gregory Z, Ferl, James, Ziai, Sandra Sanabria, Bohorquez, Sebastian, Guelman, Xiangdan, Wang, Jihong, Yang, Minh Michael, Phan, Van, Nguyen, Shan, Chung, Christine, Yu, Jeff, Tinianow, Stijn Jan Hein, Waaijer, Alex, De Crespigny, Jan, Marik, C Andrew, Boswell, Tanja, Zabka, Karin, Staflin, Simon-Peter, Williams
Publikováno v:
European journal of nuclear medicine and molecular imaging. 50(2)
ZED8 is a novel monovalent antibody labeled with zirconium-89 for the molecular imaging of CD8. This work describes nonclinical studies performed in part to provide rationale for and to inform expectations in the early clinical development of ZED8, s
Autor:
Herman, Gill, Richard, Seipert, Vincent M, Carroll, Alexandra, Gouasmat, Jian, Yin, Annie, Ogasawara, Isabella, de Jong, Minh Michael, Phan, Xiangdan, Wang, Jihong, Yang, Ohad, Ilovich, Jan, Marik, Simon-Peter, Williams
Publikováno v:
The AAPS journal. 22(2)
Immuno-PET is a molecular imaging technique utilizing positron emission tomography (PET) to measure the biodistribution of an antibody species labeled with a radioactive isotope. When applied as a clinical imaging technique, an immuno-PET imaging age
Autor:
Tang, Tang, Herman S, Gill, Annie, Ogasawara, Jeff N, Tinianow, Alexander N, Vanderbilt, Simon-Peter, Williams, Georgia, Hatzivassiliou, Sharla, White, Wendy, Sandoval, Kevin, DeMent, Mengling, Wong, Jan, Marik
Publikováno v:
Nuclear medicine and biology. 51
Indoleamine and tryptophan 2,3-dioxygenases (IDO1 and TDO2) are pyrrolases catalyzing the oxidative cleavage of the 2,3-double bond of L-tryptophan in kynurenine pathway. In the tumor microenvironment, their increased activity prevents normal immune
Autor:
Annie Ogasawara, Alexander N. Vanderbilt, Jan Marik, Anton G.T. Terwisscha van Scheltinga, Dongwei Li, Nidhi Gupta, Glenn Pacheco, Suzie J. Scales, Ron Firestein, Jeff N. Tinianow, Simon-Peter Williams
Publikováno v:
Molecular cancer therapeutics, 16(1), 134-142. AMER ASSOC CANCER RESEARCH
Antibody–drug conjugates (ADC) use monoclonal antibodies (mAb) as vehicles to deliver potent cytotoxic drugs selectively to tumor cells expressing the target. Molecular imaging with zirconium-89 (89Zr)-labeled mAbs recapitulates similar targeting b
Autor:
Annie Ogasawara, Jan Marik, Alexander N. Vanderbilt, Herman Gill, Judith E. Flores, Sharon Yee, Avi Ashkenazi, Jeff N. Tinianow, Simon-Peter Williams
Publikováno v:
Nuclear medicine and biology. 40(1)
An immunoPET imaging probe for the detection of phosphatidylserine was developed and tested in animal models of human cancer treated with pro-apoptotic therapy. We hypothesized that the relatively long plasma half-life of a probe based on a full-leng
Autor:
Judith E. Flores, Alexander N. Vanderbilt, Simon-Peter Williams, Annie Ogasawara, Leanne McFarland
Publikováno v:
Molecular imaging and biology. 10(4)
We sought to identify an anesthetic regime that, unlike isoflurane in air, would maintain glucose homeostasis in mice undergoing Positron emission tomography (PET) imaging with 2-deoxy-2-[18F]fluoro-d-glucose (FDG). FDG uptake was also measured in no