Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael Oberst"'
Autor:
Kelly McGlinchey, Scott A. Hammond, John Hood, Ross Stewart, Grace Adjei, Weimin Chen, John Andrews, Darren J. Schofield, Robert W. Wilkinson, Maria A T Groves, Leslie Wetzel, Jennifer L. Percival-Alwyn, Michael Oberst, Mateusz Rytelewski, LeeAnn Machiesky, Andrew Leinster, Claire Dobson, Nadia Luheshi, Raymond Rothstein, Michelle Morrow, Amanda Watkins
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Preclinical studies of PD-L1 and CTLA-4 blockade have relied heavily on mouse syngeneic tumor models with intact immune systems, which facilitate dissection of immunosuppressive mechanisms in the tumor microenvironment. Commercially developed monoclo
Autor:
Andrew W. Sylwester, James Hair, Scott A. Hammond, Qun Du, Nicholas Buss, Lolke de Haan, Michael Oberst, Kathy Mulgrew, Louis J. Picker, Michael K. Axthelm, Melissa Damschroder, Hui Feng, Andrew D. Weinberg, Haesun Park, Shino Hanabuchi, Steven Eck, Stacy R. Kentner, Chad Morris, Kelly McGlinchey, Nicholas P. Morris, Andrew J. Pierce, Catherine Auge
Publikováno v:
Molecular Cancer Therapeutics. 17:1024-1038
Ligation of OX40 (CD134, TNFRSF4) on activated T cells by its natural ligand (OX40L, CD252, TNFSF4) enhances cellular survival, proliferation, and effector functions such as cytokine release and cellular cytotoxicity. We engineered a recombinant huma
Autor:
Lu Wen, Frank I. Comer, Michael Oberst, Mary Jane Hinrichs, Tao Zhang, Alfred E. Chang, Yangyi Bao, Yuanyuan Liu, Hannah E. Dobson, Steven R. Coats, Qiao Li, Max S. Wicha, Fu Dai, You Qin, Leiming Xia
Publikováno v:
Cell Chem Biol
We previously tested HER2-targeted antibody drug conjugates (ADC) in immunocompromised (SCID) mice, precluding evaluation of host immunity, impact on cancer stem cells (CSCs), and potential benefit when combined with PD-L1 blockade. In this study, we
Autor:
Chunhong Li, Yichao Fan, Guosheng Ren, Tingxiu Xiang, Yixiao Feng, Ying Ying, Weiyan Peng, Michael Oberst, Junhao Mu, Kathleen Kelly, Lili Li, Qian Tao
Publikováno v:
Oncotarget
// Tingxiu Xiang 1 , Yichao Fan 2 , Chunhong Li 3 , Lili Li 2 , Ying Ying 2 , Junhao Mu 1 , Weiyan Peng 1 , Yixiao Feng 1 , Michael Oberst 4 , Kathleen Kelly 4 , Guosheng Ren 1 , Qian Tao 1, 2 1 Chongqing Key Laboratory of Molecular Oncology and Epig
Autor:
Kathleen Kelly, Chenfu Yuan, Qian Tao, Thomas C. Putti, Cui Tan, Michael Oberst, Lei Xiong, Guosheng Ren, Lili Li, Xuedong Yin, Xianwei Su, Tingxiu Xiang
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29783 (2012)
PLoS ONE
PLoS ONE
Background Breast cancer (BrCa) is a complex disease driven by aberrant gene alterations and environmental factors. Recent studies reveal that abnormal epigenetic gene regulation also plays an important role in its pathogenesis. Ubiquitin carboxyl- t
Autor:
Juan Juan Yin, Kirsten Tracy, Kathleen Kelly, Michael Oberst, Claire Pollock, Philip Martin, Monika Chock
A hallmark of metastasis is organ specificity; however, little is known about the underlying signaling pathways responsible for the colonization and growth of tumor cells in target organs. Since tyrosine kinase receptor activation is frequently assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f782b1a8bbe76bbacc2b7166a6d64b0e
https://europepmc.org/articles/PMC2169046/
https://europepmc.org/articles/PMC2169046/