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pro vyhledávání: '"Luc, Stoven"'
Autor:
Marie Christine Copin, Luc Stoven, Nathalie Marchand, David Tulasne, Alexis B. Cortot, Maeva Kyheng, Simon Baldacci, Vincent Cockenpot, Zoulika Kherrouche, Elisabeth Werkmeister
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 125
Background Five to 20% of metastatic EGFR-mutated non-small cell lung cancers (NSCLC) develop acquired resistance to EGFR tyrosine kinase inhibitors (EGFR-TKI) through MET amplification. The effects of MET amplification on tumor and patient phenotype
Autor:
Luc Stoven, Yvan de Launoit, Elisabeth Werkmeister, David Tulasne, Alexis B. Cortot, Zoulika Kherrouche, Anne Chotteau-Lelievre, Didier Monté
Publikováno v:
Molecular Oncology
Molecular Oncology, Elsevier, 2015, 9 (9), pp.1852-1867. ⟨10.1016/j.molonc.2015.07.001⟩
Molecular Oncology, 2015, 9 (9), pp.1852-1867. ⟨10.1016/j.molonc.2015.07.001⟩
Molecular Oncology, Elsevier, 2015, 9 (9), pp.1852-1867. ⟨10.1016/j.molonc.2015.07.001⟩
Molecular Oncology, 2015, 9 (9), pp.1852-1867. ⟨10.1016/j.molonc.2015.07.001⟩
International audience; Various solid tumors including lung or gastric carcinomas display aberrant activation of the Met receptor which correlates with aggressive phenotypes and poor prognosis. Although downstream signaling of Met is well described,