Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Karin Jirström"'
Autor:
Laoighse Mulrane, René Bernards, William M. Gallagher, Aisling O'Connor, Lisa Dwane, Brenton Cavanagh, Annette M.G. Dirac, Brian Mooney, Elspeth Ward, Benedikt M. Kessler, Anna M. Blümel, Adan Pinto-Fernandez, Karin Jirström, Triona Ni Chonghaile, Bruce Moran, Darran P. O'Connor, Sudipto Das
Publikováno v:
Cancer Research. 80:5076-5088
Approximately 70% of breast cancers express estrogen receptor α (ERα) and depend on this key transcriptional regulator for proliferation and differentiation. While patients with this disease can be treated with targeted antiendocrine agents, drug r
Autor:
Annika Dejmek, Charlene Lin, Isabella Robles, Zena Werb, Merel van Gogh, Kiarash Salari, Chih Yang Wang, Hugo Gonzalez, Karin Jirström, Catharina Hagerling
Publikováno v:
Proceedings of the National Academy of Sciences. 116:21704-21714
Metastatic behavior varies significantly among breast cancers. Mechanisms explaining why the majority of breast cancer patients never develop metastatic outgrowth are largely lacking but could underlie the development of novel immunotherapeutic targe
Autor:
Sara Wahlin, Karolina Boman, Bruce Moran, Björn Nodin, William M. Gallagher, Emelie Karnevi, Karin Jirström
Publikováno v:
BMC Cancer
BMC Cancer, Vol 22, Iss 1, Pp 1-15 (2022)
BMC Cancer, Vol 22, Iss 1, Pp 1-15 (2022)
Background The response to neoadjuvant cisplatin-based chemotherapy (NAC) in muscle-invasive bladder cancer (MIBC) is impaired in up to 50% of patients due to chemoresistance, with no predictive biomarkers in clinical use. The proto-oncogene RNA-bind
Autor:
Bengt Phung, Per Eystein Lønning, Jillian Howlin, Frida Rosengren, Mattias Aine, Rizwan Haq, Göran Jönsson, Martin Lauss, Karolina Holm, Markus Ringnér, David E. Fisher, Karin Jirström, Katja Harbst, Johan Staaf, Christian Busch, Åke Borg, Jürgen Geisler, Helena Cirenajwis
Publikováno v:
Journal of Investigative Dermatology. 135(7):1820-1828
The microphthalmia-associated transcription factor (MITF) is a key regulator of melanocyte development and a lineage-specific oncogene in melanoma; a highly lethal cancer known for its unpredictable clinical course. MITF is regulated by multiple intr
Autor:
Louise Walsh, Bo Li, John Crown, Karin Jirström, Helen Bardwell, Alexander Gaber, Yue Fan, Thierry Dubois, Suet-Feung Chin, Carlos Caldas, Stephen F. Madden, Elena Provenzano, Aisling O'Connor, Sabine C. Linn, Gillian O'Hurley, Girish Mallya Udupi, Triona Ni Chonghaile, William M. Gallagher, Jesuchristopher Joseph, Darran P. O'Connor, Emer Conroy, Finbarr Tarrant, Rut Klinger
Publikováno v:
Cancer Research, 77(14), 3834. American Association for Cancer Research Inc.
Triple-negative breast cancer (TNBC) patients commonly exhibit poor prognosis and high relapse after treatment, but there remains a lack of biomarkers and effective targeted therapies for this disease. Here, we report evidence highlighting the cell-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a467fd772b6b0c675614209f3d89c0
https://dspace.library.uu.nl/handle/1874/355880
https://dspace.library.uu.nl/handle/1874/355880
Autor:
Chrysostomi Gialeli, Wen Guo Jiang, Anna M. Blom, Akira Orimo, Michael Bartoschek, Kristian Pietras, Marcin Okroj, Sioned Owen, Karin Jirström, Astrid Escudero-Esparza
Publikováno v:
Oncotarget
Human CUB and Sushi multiple domains 1 (CSMD1) is a membrane-bound complement inhibitor suggested to act as a putative tumor suppressor gene, since allelic loss of this region encompassing 8p23 including CSMD1 characterizes various malignancies. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05f275260c3656260e1f9b8a314fca5
https://orca.cardiff.ac.uk/id/eprint/95525/1/12729-190852-2-PB.pdf
https://orca.cardiff.ac.uk/id/eprint/95525/1/12729-190852-2-PB.pdf
Autor:
Stephen P. Ethier, Balázs Tahin, Daniel Bexell, Sofie Mohlin, Roni Allaoui, Karin Leandersson, Catharina Hagerling, Robin L. Anderson, Karin Jirström, Caroline Bergenfelz, Sven Påhlman, Christer Larsson, Zena Werb, Martin Johansson, Kiarash Salari
Publikováno v:
Allaoui, R; Bergenfelz, C; Mohlin, S; Hagerling, C; Salari, K; Werb, Z; et al.(2016). Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers. Nature Communications, 7, 13050. doi: 10.1038/ncomms13050. UCSF: Retrieved from: http://www.escholarship.org/uc/item/066559w3
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature communications, vol 7, iss 1
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature communications, vol 7, iss 1
Triple-negative (TN) breast cancers (ER−PR−HER2−) are highly metastatic and associated with poor prognosis. Within this subtype, invasive, stroma-rich tumours with infiltration of inflammatory cells are even more aggressive. The effect of myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65fa6a624b0c211761a10ab72a5cf06
http://www.escholarship.org/uc/item/066559w3
http://www.escholarship.org/uc/item/066559w3
Autor:
Andy C.-M. Chang, Martin Augsten, Per Sandström, Srinivas Veerla, Linda Bojmar, Sara Kiflemariam, Arne Östman, Per-Henrik Edqvist, Karin Jirström, Helgi Birgisson, María Virtudes Céspedes, Christina Hägglöf, Roger R. Reddel, Alberto Gallardo, Ramon Mangues, Tobias Sjöblom, Cristina Peña, Eleonor Olsson, Maja Bradic Lindh, Artur Mezheyeuski
Publikováno v:
Cancer Research. 73:1287-1297
Platelet-derived growth factor (PDGF) receptor signaling is a major functional determinant of cancer-associated fibroblasts (CAF). Elevated expression of PDGF receptors on stromal CAFs is associated with metastasis and poor prognosis, but mechanism(s
Autor:
Urban Rydberg, Hanna Tegel, Sanjay Navani, Jan Mulder, Mattias Forsberg, Holger Berling, Jacob Odeberg, Martin Zwahlen, Jochen M. Schwenk, Per Oksvold, Johan Rockberg, Caroline Kampf, Evelina Sjöstedt, Peter Nilsson, Daniel Klevebring, Sophia Hober, Emma Lundberg, Linn Fagerberg, IngMarie Olsson, Cajsa Älgenäs, Per-Henrik Edqvist, Mathias Uhlén, Fredrik Pontén, Anna Asplund, Cristina Al-Khalili Szigyarto, Paul Hudson, Lisa Björling, Karin Jirström, Kalle von Feilitzen, Jenny Ottosson Takanen, Marie Skogs, Åsa Sivertsson
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research; Vol 12
Journal of Proteome Research; Vol 12
A gene-centric Human Proteome Project has been proposed to characterize the human protein-coding genes in a chromosome-centered manner to understand human biology and disease. Here, we report on the protein evidence for all genes predicted from the g
Autor:
Victor Pontén, Gabriela Gremel, Karin Jirström, Lisa Rydén, Kristina Magnusson, Fredrik Pontén, Mathias Uhlén, Anna Dimberg
Publikováno v:
BMC Cancer
Background Anillin (ANLN), an actin-binding protein required for cytokinesis, has recently been presented as part of a prognostic marker panel in breast cancer. The objective of the current study was to further explore the prognostic and functional v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e14207cdfe35bd7f2b7aaef88a33784
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-264237
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-264237