Zobrazeno 1 - 10
of 34
pro vyhledávání: '"He Ren"'
Autor:
Qian Qiu, Di Lu, Gengqi Liu, Xingyue Yang, Jiexin Li, He Ren, Jingang Liu, Boyang Sun, Yumiao Zhang
Publikováno v:
Bioconjugate Chemistry. 33:1944-1952
In the tumor microenvironment, there exist microorganisms that metabolize anticancer drugs, leading to chemotherapy failure. To solve this problem, herein, we develop antibiotic and anticancer drug co-delivery micelles, termed colistin crosslinked ge
Publikováno v:
Analytical Chemistry. 94:10610-10616
To study the heterogeneity of circulating tumor cells (CTCs) is of crucial importance to analyze cancer progression and metastasis. However, in situ detection of highly heterogeneous CTCs in peripheral blood still faces an elusive challenge. Here, we
Autor:
Xiaoyuan Sun, Huijun Chu, Ke Lei, Yandong Ci, Haijun Lu, Jia Wang, Meng Zhou, He Ren, Tongsen Zheng
Publikováno v:
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 22(6)
G-protein-coupled receptor 120 (GPR120) is a long-chain unsaturated fatty acid receptor, which regulates glucose metabolism and lipid. To date, there are disputes on the roles of GPR120 in the pathogenesis of cancer. Besides, little is known about it
Autor:
Mei Xue, Lingqiang Lin, Fang Wang, He Ren, Xiaoyu Li, Yi Zhu, Xiangyang Liu, Zipeng Xie, Ying Cheng, Ting Li, Shaoxian Duan
Publikováno v:
Cancer Letters. 495:200-210
In addition to their hypoglycemic effect, sodium-glucose cotransporter 2 (SGLT2) inhibitors have many other benefits. In the present study, we examine the anticancer effect of the SGLT2 inhibitor empagliflozin using cervical carcinoma models. In vivo
Publikováno v:
ACS applied bio materials. 4(6)
Oxygen-dependent photodynamic therapy (PDT) is hindered by the limited availability of endogenous oxygen in solid tumors and low tumor accumulation of photosensitizers. Herein, we developed a biocompatible cancer-targeted therapeutic nanosystem based
Autor:
Yan Su, Del Nonno Franca, Zhaolie Chen, Yunyun Wang, Hongyan Huang, Yichao Zhu, Haoran Peng, You Zheng, Lihua Gao, Bo Zhang, Xiaoning Wang, Chenxi Wang, Xiaoyi Jiang, Ping Zhao, Hanping Shi, Mauro Piacentini, Meifang He, Meng Tang, Xiu-Wu Bian, Zubiao Niu, Yuqi Wang, Xiaohong Yao, Gerry Melino, Zhengrong Zhang, He Ren, Liang Liu, Qiang Sun
Publikováno v:
Cell Death and Differentiation
Cell death and differentiation 28(9), 2765-2777 (2021). doi:10.1038/s41418-021-00782-3
Cell death and differentiation 28(9), 2765-2777 (2021). doi:10.1038/s41418-021-00782-3
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is highly contagious and causes lymphocytopenia, but the underlying mechanisms are poorly understood. We demonstrate here that heterotypic cell-in-cell structures with lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d5a08190f5fc3db95edf0d89afd8f6
https://doi.org/10.21203/rs.3.rs-353991/v1
https://doi.org/10.21203/rs.3.rs-353991/v1
Autor:
Jihui Hao, Liangliang Wu, Chungen Lan, Xiuchao Wang, Rujiang Jia, Bodong Zhou, Mingxiao Lang, Zengxun Li, Haotian Wang, Xin Li, Yan Sun, He Ren, Tiansuo Zhao, Hongwei Wang
Publikováno v:
Cancer Letters. 453:10-20
Perineural invasion (PNI) is a typical pathological feature of pancreatic ductal adenocarcinoma (PDAC). PNI is associated with poor prognosis of PDAC patients, however, the underlying molecular mechanisms in the development of PNI have not been fully
Autor:
Shengyu Yang, Yang Xu, Jihui Hao, Antao Chang, Hongwei Wang, Tiansuo Zhao, Yang Li, Xiuchao Wang, Jie Dong, Na Li, Keping Xie, Chongbiao Huang, Yi Ge, He Ren, Zengxun Li
Publikováno v:
Clin Cancer Res
Purpose: Oxygen and glucose deprivation is a common feature of the solid tumor. Regulatory network underlying the adaptation of cancer cells to the harsh microenvironment remains unclear. We determined the mechanistic role of LIM and senescent cell a
Publikováno v:
Clin Exp Immunol
Summary Hepatic inflammatory response is a risk factor for liver cancer initiation and progression. Interleukin (IL)-35 is the newest member of the IL-12 cytokine family, and has been reported to play an essential role in the immunosuppressive liver
Autor:
Yan Peng, Xiao-Yan He, Si-Xue Cheng, Jian-Ping Zhang, Shu-Lun Ai, Bo-Ya Liu, Chang Xu, Xiao-He Ren
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 32(17)
Effective reversal of tumor immunosuppression is of critical importance in cancer therapy. A multifunctional delivery vector that can effectively deliver CRISPR-Cas9 plasmid for β-catenin knockout to reverse tumor immunosuppression is constructed. T