Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Antao Chang"'
Autor:
Liangliang, Wu, Yi, Ge, Yudong, Yuan, Hui, Li, Huizhi, Sun, Chao, Xu, Yifei, Wang, Tiansuo, Zhao, Xiuchao, Wang, Jing, Liu, Song, Gao, Antao, Chang, Jihui, Hao, Chongbiao, Huang
Publikováno v:
Cancer Letters. 548:215864
Gemcitabine (GEM) resistance is one of the major causes of treatment failure in pancreatic ductal adenocarcinoma (PDAC) in clinic. Here, through CRISPR/Cas9 activation library screen, we found that MTA3 mediates the GEM resistance of PDAC and thus mi
Autor:
Guanwen Wang, Shan Huang, Rong Xiang, Yanhua Liu, Wen Shi, Mengyao Xu, Yanan Chen, Miao Li, Qiong Wang, Shuang Yang, Peiqing Sun, Chongbiao Huang, Antao Chang, Xiaoli Dong
Publikováno v:
Journal of Molecular Cell Biology
Metastases are the main cause of cancer-related mortality in breast cancer. Although significant progress has been made in the field of tumor metastasis, the exact molecular mechanisms involved in tumor metastasis are still unclear. Here, we report t
Autor:
Guanwen Wang, Juan Wang, Antao Chang, Dongmei Cheng, Shan Huang, Dan Wu, Sherona Sirkisoon, Shuang Yang, Hui-Kuan Lin, Hui-Wen Lo, Rong Xiang, Peiqing Sun
Publikováno v:
Oncogene
While mechanisms for metastasis were extensively studied in cancer cells from patients with detectable tumors, pathways underlying metastatic dissemination from early lesions before primary tumors appear are poorly understood. Her2 promotes breast ca
Autor:
Huimin Jiang, Huimin Wei, Hang Wang, Zhaoyang Wang, Jianjun Li, Yang Ou, Xuechun Xiao, Wenhao Wang, Antao Chang, Wei Sun, Li Zhao, Shuang Yang
Publikováno v:
Cell deathdisease. 13(3)
Aerobic glycolysis (the Warburg effect) has been demonstrated to facilitate tumor progression by producing lactate, which has important roles as a proinflammatory and immunosuppressive mediator. However, how aerobic glycolysis is directly regulated i
Autor:
Shengyu Yang, Yang Xu, Jihui Hao, Antao Chang, Hongwei Wang, Tiansuo Zhao, Yang Li, Xiuchao Wang, Jie Dong, Na Li, Keping Xie, Chongbiao Huang, Yi Ge, He Ren, Zengxun Li
Publikováno v:
Clin Cancer Res
Purpose: Oxygen and glucose deprivation is a common feature of the solid tumor. Regulatory network underlying the adaptation of cancer cells to the harsh microenvironment remains unclear. We determined the mechanistic role of LIM and senescent cell a
Autor:
Rong Xiang, Zhenglu Wang, Renle Du, Shan Jiang, Yuzhi Shi, Ruifang Gao, Wenzhi Shen, Yan Fang, Antao Chang, Chenghu Liu, Lei Liu, Shuang Zhou, Na Li
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 8, Iss 5, Pp 2325-2337 (2019)
Cancer Medicine, Vol 8, Iss 5, Pp 2325-2337 (2019)
Toll‐like receptor 4 (TLR4) plays an essential role in cancer progress. Here, we find that the expression of TLR4 in relapsed human hepatocellular carcinoma (HCC) clinical samples is higher than that in the non‐relapsed ones, which leads us to ex
Autor:
Dongmei Cheng, Dan Wu, Xiaoming Tan, Shan Huang, Peiqing Sun, Qiong Wang, Rong Xiang, Shaorong Zhao, Antao Chang, Juan Wang, Guanwen Wang, Shuang Yang, Andy T Liu
Publikováno v:
Oncogene
Cancer can metastasize from early lesions without detectable tumors. Despite extensive studies on metastasis in cancer cells from patients with detectable primary tumors, mechanisms for early metastatic dissemination are poorly understood. Her2 promo
Autor:
Peiqing Sun, Weijun Su, Chen Zhou, Guanwen Wang, Juan Wang, Shaorong Zhao, Shuangtao Zhao, Shan Huang, Rong Xiang, Yan Fang, Pengling Jiang, Peng Wang, Antao Chang
Publikováno v:
Oncotarget
// Yan Fang 1 , Juan Wang 1 , Guanwen Wang 1 , Chen Zhou 1 , Peng Wang 1 , Shuangtao Zhao 1 , Shaorong Zhao 1 , Shan Huang 2 , Weijun Su 1, 2 , Pengling Jiang 3 , Antao Chang 1, 2 , Rong Xiang 1 , Peiqing Sun 1, 2 1 Department of Immunology, School o
Autor:
He Ren, Wei Zhang, Chongbiao Huang, Na Li, Lin Luo, Zengxun Li, Antao Chang, Yang Li, Xiuchao Wang, Shengyu Yang, Yanan Chen, Tiansuo Zhao, Zhimin Wang, Jingjing Shi, Jihui Hao
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
Interleukin 35 (IL-35) is a novel member of the IL-12 family, consisting of an EBV-induced gene 3 (EBI3) subunit and a P35 subunit. IL-35 is an immune-suppressive cytokine mainly produced by regulatory T cells. However, the role of IL-35 in cancer me
Autor:
Antao Chang, Zengxun Li, Na Li, Xiuchao Wang, Hongwei Wang, Shengyu Yang, Chongbiao Huang, Tiansuo Zhao, Song Gao, He Ren, Jihui Hao, Yang Li
Publikováno v:
Gastroenterology. 154(3)
Background & Aims Cells of the monocyte lineage contribute to tumor angiogenesis. Interleukin 35 (IL35) is a member of the IL12 family produced by regulatory, but not effector, T cells. IL35 is a dimer comprising the IL12 alpha and IL27 beta chains,