Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Xi Yang"'
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background As one of the leading threats for health among women worldwide, breast cancer has high morbidity and mortality. Surgical resection is the major clinical intervention for primary breast tumor, nevertheless high local recurrence risk and bre
Publikováno v:
Biochemical and Biophysical Research Communications. 576:7-14
In Asia, prostate cancer is becoming a growing concern, impacting both socially and economically, compared with what is seen in western countries. Hence, it is essential to know the mechanisms associated with the development and tumorigenesis of PCa
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Pyruvate kinase M2 as a key rate-limiting enzyme in glycolysis, it plays a critical role in metabolic reprogramming and carcinogenesis. However, whether PKM2 can promote immunosuppressive microenvironment formation remains unknown in head and neck sq
Publikováno v:
Oral Diseases. 28:2139-2148
Treatment of oral squamous cell carcinoma remains a challenge due to a high incidence of treatment resistance, which is followed by tumor recrudescence and metastasis to the lymph nodes. Thus, it is important to explore novel inhibitors of OSCC. Here
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 37, Iss 4, Pp 276-285 (2021)
MicroRNAs (miRNAs) are dysregulated in human ovarian carcinoma (OC). But the mechanism underlying miR‐10a‐5p in regulating the progression of OC need deeply explored. In the current study, we observed that miR‐10a‐5p was down‐expressed in O
Autor:
Xi Yang, Cui Hua Liu, Ling Li, Pupu Ge, Lihua Qiang, Qiyao Chai, Yong Zhang, Zehui Lei, Yu Cui, Dongdong Zhao, Zhe Lu, Bo Wu, Jing Wang, Lingqiang Zhang, Conghui Han
Publikováno v:
The FASEB Journal. 34:14631-14644
During spaceflight, astronauts are subjected to various physical stressors including microgravity, which could cause immune dysfunction and thus potentially predispose astronauts to infections and illness. However, the mechanisms by which microgravit
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Strategies for eradicating cancer stem cells (CSCs) are urgently required because CSCs are resistant to anticancer drugs and cause treatment failure, relapse and metastasis. Here, we show that photoactive functional nanocarbon complexes exhibit uniqu
Autor:
Chen-Xi Yang, Xin Chang, Yu-Yang Bi, Hu-Lin Jiang, Zhi-Qi Zhang, Lei Xing, Zhiqiang Yu, Tian-Jiao Zhou
Publikováno v:
Molecular Pharmaceutics. 17:1300-1309
Chemotherapy still accounts for a large proportion of the treatments of tumors, but the drug resistance and side effects caused by long-term chemotherapy should not be underestimated. In this work, the drug combination strategy has been widely develo
Autor:
Dongming Zhou, Jing Pan, Chuo Li, Erlie Jiang, Xiaolei Sun, Sheng Wang, Xi Yang, Xiaoming Feng, Shiyu Zuo, Qing Niu, Huifang Huang, Haidong Cui, Guoling Wang, Min Liu, Zihao Fang, Qi Deng, Yonghui Xia, Yanyu Jiang, Yuan Meng
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-6 (2021)
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-6 (2021)
CD19 chimeric antigen receptor (CAR)-T cells have been used to treat patients with refractory chronic lymphocytic leukemia (CLL). However, approximately 50% of patients do not respond to this therapy. To improve the clinical outcome of these patients
Publikováno v:
Oncology Research
Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), afatinib, has been approved for treating EGFR mutant lung cancer patients, but the mechanism of acquired resistance to afatinib has not been well