Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jee H. Jung"'
Publikováno v:
Marine drugs. 20(3)
Through activity-guided fractionation, a new triterpene (asperflagin
Publikováno v:
Bioorganic chemistry. 96
In our previous study, a PPAR-γ agonist (+)-(R,E)-6a1 was elaborated as an anti-inflammatory lead. However, in silico analysis showed that (+)-(R,E)-6a1 lacks key hydrogen bonding with Tyr473 of PPAR-γ LBD (ligand binding domain). To facilitate add
Publikováno v:
Journal of Natural Products. 81:356-363
An investigation of the jellyfish-derived fungus Penicillium chrysogenum J08NF-4 led to the isolation of two new meroterpene derivatives, chrysogenester (1) and 5-farnesyl-2-methyl-1-O-methylhydroquinone (2), and four known farnesyl meroterpenes. Doc
Publikováno v:
Marine Drugs
Marine Drugs, Vol 19, Iss 417, p 417 (2021)
Volume 19
Issue 8
Marine Drugs, Vol 19, Iss 417, p 417 (2021)
Volume 19
Issue 8
Peroxisome proliferator-activated receptor (PPAR) expression has been implicated in pathological states such as cancer, inflammation, diabetes, and neurodegeneration. We isolated natural PPAR agonists—eight 2,5-diketopiperazines—from the jellyfis
Publikováno v:
Molecular Medicine Reports. 14:2691-2696
Vibrio vulnificus is known to induce severely fulminant and fatal septicemia in susceptible hosts. In the present study, the antimicrobial activity of natural marine product-derived compounds against V. vulnificus, were investigated in vitro and in v
Autor:
Hyung Ryong Moon, Eunok Im, Sujin Son, Yunna Lee, Jieun Choo, Jee H. Jung, Charalabos Pothoulakis, Xin-jia Yan, Seong Jin Kim, Tae Hwan Noh
Publikováno v:
The Journal of biological chemistry, vol 290, iss 42
Choo, J; Lee, Y; Yan, XJ; Noh, TH; Kim, SJ; Son, S; et al.(2015). A Novel Peroxisome Proliferator-activated Receptor (PPAR)y Agonist 2-Hydroxyethyl 5-chloro-4, 5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis. Journal of Biological Chemistry, 290(42), 25609-25619. doi: 10.1074/jbc.M115.673046. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3038w8kf
Choo, J; Lee, Y; Yan, XJ; Noh, TH; Kim, SJ; Son, S; et al.(2015). A Novel Peroxisome Proliferator-activated Receptor (PPAR)y Agonist 2-Hydroxyethyl 5-chloro-4, 5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis. Journal of Biological Chemistry, 290(42), 25609-25619. doi: 10.1074/jbc.M115.673046. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3038w8kf
© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Inflammatory bowel disease (IBD) is a chronic inflammatory disease with increasing incidence and prevalence worldwide. Here we investigated the newly synthesized jasmonate a
Publikováno v:
Marine Drugs, Vol 15, Iss 1, p 7 (2017)
Marine Drugs; Volume 15; Issue 1; Pages: 7
MARINE DRUGS(15): 1
Marine Drugs
Marine Drugs; Volume 15; Issue 1; Pages: 7
MARINE DRUGS(15): 1
Marine Drugs
Previously, the authors found that 4-hydroxy-2-(4-hydroxyphenethyl) isoindoline-1,3-dione (PD1) (a phthalimide analogue) bound to and activated peroxisome proliferator-activated receptor-gamma (PPAR-gamma). Since PPAR-gamma suppresses inflammatory re
Autor:
Huayue Li, Jaewon Lee, Eun La Kim, Eun-Hee Kim, Hyung Sik Kim, Haibo Wang, Mingzhi Su, Jee H. Jung
Publikováno v:
Bioorganicmedicinal chemistry. 24(13)
Two new cystine knot peptides, asteropsins F (ASPF) and G (ASPG), were isolated from the marine sponge Asteropus sp. ASPF and ASPG are composed of 33 and 32 amino acids, respectively, and contain six cysteines which are involved in three disulfide bo
Autor:
Jian Lin Li, Bin Xiao, Hae Young Chung, Minhi Park, Juan Liu, Jongki Hong, Jun Yin, Eun La Kim, Jee H. Jung
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:4954-4961
On the basis of a marine fungal phthalide (paecilocin A) skeleton, we synthesized 20 analogs and evaluated them for peroxisome proliferator-activated receptor gamma (PPAR-γ) binding and activation. Among these analogs, 6 and 7 had significant PPAR-
Autor:
Hung The Dang, Gyeoung Jin Kang, Eun Sook Yoo, Jongki Hong, Jae Sue Choi, Hyung Sik Kim, Hae Young Chung, Jee H. Jung
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:1520-1527
A series of endogenous fatty acid amides and their analogues (1-78) were prepared, and their inhibitory effects on pro-inflammatory mediators (NO, IL-1β, IL-6, and TNF-α) in LPS-activated RAW264.7 cells were evaluated. Their inhibitory activity on