Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Mingshan Niu"'
Autor:
Kailin Xu, Mingshan Niu, Yuanyuan Qin, Xuguang Song, Pu Yang, Feng Zhu, Yu Tian, Mengdi Liu, Xiaoshen Sun, Lingyu Zeng, Dongmei Yan, Cai Sun, Zhenyu Li, Jun Jiao, Linyan Xu, Xiang Gao, Wei Sang
Publikováno v:
Journal of Cancer
Despite advancement in the treatment of diffuse large B-cell lymphoma (DLBCL), many patients tend to relapse or become refractory after initial therapy. Therefore, it is essential to identify novel therapeutic targets and drugs, understand the molecu
Autor:
Guanzheng Liu, Mingshan Niu, Chenglong Yue, Rutong Yu, Xuejiao Liu, Xiangyu Chen, Huan Li, Lin Shi, Qianqian Shan, Shangfeng Gao, Yifeng Wang, Qiyu Cao, Jie Wang
Publikováno v:
Journal of Cellular and Molecular Medicine
Glioblastoma multiforme (GBM) is the most common malignant tumour in the adult brain and hard to treat. Nuclear factor κB (NF‐κB) signalling has a crucial role in the tumorigenesis of GBM. EGFR signalling is an important driver of NF‐κB activa
Autor:
Di Zhou, Yulong Chong, Yifeng Wang, Huan Li, Lin Shi, Yiming Tu, Xuejiao Liu, Xu Zhang, Mingshan Niu, Guanzheng Liu, Rutong Yu, Shangfeng Gao, Sijin Wu
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-12 (2020)
Cancer Cell International
Cancer Cell International
BackgroundActivation of nuclear factor-kappa B (NF-κΒ) through DNA damage is one of the causes of tumor cell resistance to radiotherapy. Chromosome region 1 (CRM1) regulates tumor cell proliferation, drug resistance, and radiation resistance by reg
Autor:
Runqiu Wu, Wanhong Zhang, Rutong Yu, Mingshan Niu, Jiefeng Yu, Guanzheng Liu, Xuejiao Liu, Huan Li, Xu Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
Glioblastoma multiforme (GBM), a fatal brain tumour with no available targeted therapies, has a poor prognosis. At present, radiotherapy is one of the main methods to treat glioma, but it leads to an obvious increase in inflammatory factors in the tu
Autor:
Jie Wang, Rutong Yu, Chenglong Yue, Mingshan Niu, Qiyu Cao, Xiangyu Chen, Shangfeng Gao, Shengsheng Li, Lin Shi, Qianqian Shan, Huan Li, Xuejiao Liu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Glioblastoma (GBM) is a fatal brain tumor, lacking effective treatment. Epidermal growth factor receptor (EGFR) is recognized as an attractive target for GBM treatment. However, GBMs have very poor responses to the first- and second-genera
Autor:
Kunming Qi, Jiang Cao, Kailin Xu, Li Li, Hai Cheng, Qing-Yun Wu, Lingyu Zeng, Wei Chen, Chong Chen, Mingshan Niu, Xiao Han
Publikováno v:
OncoTargets and Therapy. 12:433-441
Jiang Cao,1,* Li Li,2,* Xiao Han,1 Hai Cheng,1 Wei Chen,1 Kunming Qi,1 Chong Chen,1 Qingyun Wu,1 Mingshan Niu,1 Lingyu Zeng,1 Kailin Xu1 1Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China; 2Departmen
Autor:
Rong Wang, Huihui Zhang, Jiawen Xu, Ninghan Zhang, Ting Pan, Xiaomin Zhong, Huanxin Zhang, Lingling Yin, Yao Yao, Qingyun Wu, Zhenyu Li, Xuejiao Liu, Kailin Xu, Mingshan Niu
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Current treatment of T-cell acute lymphoblastic leukemia (T-ALL) is primarily based on high-intensity combination chemotherapy, which has serious side effects. Therefore, developments of novel targeted therapeutics are urgently needed for treatment o
Autor:
Ning‐Ning Ding, Wei Chen, Chong Chen, Hao Feng, Mingshan Niu, Hong‐Hu Zhu, Qing-Yun Wu, Tingting Qiu, Jiang Cao, Kailin Xu
Publikováno v:
Cancer Medicine, Vol 5, Iss 11, Pp 3205-3213 (2016)
Cancer Medicine
Cancer Medicine
Homoharringtonine combined with aclarubicin and cytarabine (HAA) is a highly effective treatment for acute myeloid leukemia (AML), especially for t(8;21) AML. However, the underlying mechanisms by which HAA kills t(8;21) AML cells remain unclear. In
Autor:
Yueyue Sun, Ruosi Yao, Zhenyu Li, Dandan Xia, Lingyu Zeng, Kailin Xu, Ying Zhang, Kai Zhao, Mingshan Niu, Min Shi, Yao Yao
Publikováno v:
Oncotarget
// Yao Yao 1, 2, 4, * , Yueyue Sun 1, 2, 4, * , Min Shi 1, 2, 4, * , Dandan Xia 1, 2, 4 , Kai Zhao 1, 2, 4 , Lingyu Zeng 1, 2, 4 , Ruosi Yao 1, 2, 4 , Ying Zhang 3 , Zhenyu Li 2 , Mingshan Niu 1, 2, 4 , Kailin Xu 1, 2, 4 1 Blood Diseases Institute, X
Autor:
Ting Pan, Yuan Feng, Ninghan Zhang, Tingting Shao, Mingshan Niu, Jianlin Qiao, Rong Wang, Huihui Zhang, Kailin Xu
Publikováno v:
Blood. 134:1260-1260
Background T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive neoplasm originated from early T cell progenitors. Constitutive activation of the Notch1-signaling pathway plays an important role in T-ALL. After three shears, Notch1 generates