Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jindan Luo"'
Publikováno v:
Neoplasma. 66:704-716
Previous studies have reported that miR-107 could be utilized as a potential peripheral biomarker in prostate cancer (PCa). However, the specific functions of miR-107 in prostate cancer and its relevant mechanisms are still unknown. The aim of this r
Autor:
Xianglai Xu, Yunfu Liu, Liping Xie, Xiao Wang, Yi Zhu, Yiwei Lin, Zhenghui Hu, Zhen Liang, Xiangyi Zheng, Hong Chen, Jian Wu, Xiaodong Jin, Yeqing Mao, Xin Xu, Jindan Luo, Shiqi Li
Publikováno v:
Oncology Letters
MicroRNAs (miRNAs) are small non-coding RNAs that affect various biological processes by altering the expression of a target gene. An miRNA microarray analysis has previously revealed a significant decrease in miR-193a-3p levels in prostate cancer ti
Autor:
Ben Liu, Yeqing Mao, Xianglai Xu, Jian Wu, Xin Xu, Xiao Wang, Hong Chen, Shiqi Li, Jindan Luo, Yiwei Lin, Liping Xie, Yi Zhu, Zhen Liang, Zhenghui Hu, Xiangyi Zheng
Publikováno v:
Molecules and Cells. 38:130-137
MicroRNAs (miRNAs) are small, endogenous RNAs that play important gene-regulatory roles by binding to the imperfectly complementary sequences at the 3′-UTR of mRNAs and directing their gene expression. Here, we first discovered that miR-576-3p was
Autor:
Zhen Liang, Xianglai Xu, Liping Xie, Jindan Luo, Zhenghui Hu, Yi Zhu, Hong Chen, Xiangyi Zheng, Xin Xu, Ben Liu, Xiao Wang, Jian Wu, Yiwei Lin, Yeqing Mao, Shiqi Li
Publikováno v:
Molecular Cancer
Background Emerging evidence has suggested that dysregulation of miR-182-5p may contribute to tumor development and progression in several types of human cancers. However, its role in renal cell carcinoma (RCC) is still unknown. Methods Quantitative
Autor:
Xianglai Xu, Shiqi Li, Jian Wu, Xiangyi Zheng, Yiwei Lin, Jindan Luo, Hong Chen, Liping Xie, Xin Xu, Yi Zhu, Yeqing Mao, Zhenghui Hu
Publikováno v:
Biochemical and biophysical research communications. 441(4)
MicroRNAs (miRNAs) are non-protein-coding sequences that play a crucial role in tumorigenesis by negatively regulating gene expression. Here, we found that miR-490-5p is down-regulated in human bladder cancer tissue and cell lines compared to normal
Autor:
Xianglai Xu, Jian Wu, Shiqi Li, Xin Xu, Hong Chen, Xiangyi Zheng, Yeqing Mao, Yi Zhu, Jindan Luo, Zhenghui Hu, Yiwei Lin, Liping Xie
Publikováno v:
Journal of Translational Medicine
Background Increasing evidence has suggested that dysregulation of certain microRNAs (miRNAs) may contribute to human disease including carcinogenesis and tumor metastasis in human. miR-124-3p is down-regulated in various cancers, and modulates proli
Publikováno v:
Asian journal of andrology. 11(6)
p27 is a cyclin-dependent kinase inhibitor that regulates the progression of cells from G(1) to S phase of the cell cycle. Loss of p27 has been associated with disease progression and with an unfavourable outcome in prostate cancer. In this study, we
Publikováno v:
Cancer investigation. 27(4)
Prostate cancer (PC), which responds well to androgen ablation initially, invariably progresses to treatment resistance. The so-called androgen-independent PC is also a concern, since there is no effective therapy so far. Nkx3.1 is a putative prostat
Publikováno v:
Asian journal of andrology. 9(3)
AIM To explore whether the anti-tumor action of 17beta-estradiol is enhanced by re-expression of the homeodomain transcription factor Nkx3.1 in PC3 human prostate cancer cells. METHODS PC3 cells were stably transfected with pcDNA3.1-Nkx3.1-His vector